CLS ( DrugBank: - )


3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
2筋萎縮性側索硬化症1
46悪性関節リウマチ1
71特発性大腿骨頭壊死症1

2. 筋萎縮性側索硬化症


臨床試験数 : 624 薬物数 : 611 - (DrugBank : 160) / 標的遺伝子数 : 172 - 標的パスウェイ数 : 225
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04948645
(ClinicalTrials.gov)
September 22, 202123/6/2021A Phase 1 Study to Investigate the Safety and Pharmacokinetics of ABBV-CLS-7262 in Patients With Amyotrophic Lateral SclerosisA Randomized, Double-Blind, Placebo-Controlled Study to Assess Safety, Tolerability, and Pharmacokinetics Following Multiple Doses of ABBV-CLS-7262 in Subjects With Amyotrophic Lateral Sclerosis Followed by an Active Treatment ExtensionALS;Amyotrophic Lateral SclerosisDrug: ABBV-CLS-7262;Drug: PlaceboCalico Life Sciences LLCAbbVieRecruiting18 Years80 YearsAll30Phase 1United States;Canada

46. 悪性関節リウマチ


臨床試験数 : 4,325 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03410940
(ClinicalTrials.gov)
January 7, 201119/1/2018PMCF Study of the CLS Brevius Stem With Kinectiv TechnologyPost-Market Clinical Follow-Up (PMCF) Study of the CLS Brevius Stem With Kinectiv TechnologyOsteoarthritis;Avascular Necrosis;Rheumatoid Arthritis;Femoral Neck Fractures;Prosthesis FailureDevice: CLS Brevius stem with Kinectiv technologyZimmer BiometNULLTerminated18 YearsN/AAll223Italy;Poland;Spain

71. 特発性大腿骨頭壊死症


臨床試験数 : 3 薬物数 : 5 - (DrugBank : 4) / 標的遺伝子数 : 4 - 標的パスウェイ数 : 11
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03112785
(ClinicalTrials.gov)
March 17, 20117/3/2017Fitmore Versus CLS Stem in Total Hip Arthroplasty. Bilateral One-stage OperationsRandomized Comparison Between the Fitmore and the CLS Stem in Patients Operated in One-stage Due to Bilateral Symptomatous Hip DiseasePrimary Hip Osteoarthritis;Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease;Bilateral Hip Disease;Surgical TreatmentDevice: Total hip arthroplasty (Fitmore or CLS uncemented femoral stem made by Zimmer-Biomet, Warshaw, USA)Sahlgrenska University Hospital, SwedenZimmer BiometActive, not recruiting35 Years75 YearsAll44N/ANULL