AMG 811 ( DrugBank: - )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
49全身性エリテマトーデス3

49. 全身性エリテマトーデス


臨床試験数 : 946 薬物数 : 722 - (DrugBank : 186) / 標的遺伝子数 : 117 - 標的パスウェイ数 : 199
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01164917
(ClinicalTrials.gov)
August 201015/7/2010Safety Study of AMG 811 in Subjects With Discoid Lupus ErythematosusA Randomized, Double-blind, Placebo-controlled, Single Dose, Two-period, Crossover Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of AMG 811 in Subjects With Discoid Lupus ErythematosusCutaneous Lupus;Discoid Lupus;Lupus;Systemic Lupus ErythematosusDrug: AMG811;Drug: AMG811 PlaceboAmgenNULLTerminated18 Years70 YearsBoth16Phase 1United States
2NCT00818948
(ClinicalTrials.gov)
March 200918/12/2008Safety Study of AMG 811 in Subjects With Systemic Lupus Erythematosus With and Without GlomerulonephritisA Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus Erythematosus With and Without GlomerulonephritisNephritis;Systemic Lupus ErythematosusDrug: AMG 811AmgenNULLCompleted18 Years70 YearsBoth56Phase 1United States;France;Hong Kong;Malaysia;Mexico;Singapore
3NCT02291588
(ClinicalTrials.gov)
December 20073/11/2014A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus ErythematosusA Phase 1, Randomized, Double-blind, Placebo-controlled, Single Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: AMG 811;Drug: PlaceboAmgenNULLCompleted18 Years65 YearsBoth26Phase 1NULL