DDrare: Database of Drug Development for Rare Diseases

205. 脆弱Ｘ症候群関連疾患　［臨床試験数：3，薬物数：3（DrugBank：2），標的遺伝子数：21，標的パスウェイ数：22］

Searched query = "Fragile X syndrome related disease", "Fragile X associated tremor/ataxia syndrome", "FXTAS"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/20/2019, 11/21/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.

Drug = Allopregnanolone; Citocoline; Memantine

No.	TrialID	Date_ enrollement	Last_Refreshed_ on	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02603926	October 2015	16 December 2017	Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone	Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone	Fragile X-associated Tremor/Ataxia Syndrome	Drug: Allopregnanolone	Randi J. Hagerman, MD		Recruiting	50 Years	85 Years	All	15	Phase 2	United States
2	NCT02197104	January 2015	16 December 2017	Citocoline for Treatment of FXTAS	Phase 2 Study of Citocoline for Treatment in Fragile X-associated Tremor/Ataxia Syndrome	Balance and Cognitive Deficits in Fragile X-associated Tremor Ataxia Syndrome	Drug: citocoline	Rush University Medical Center		Not recruiting	18 Years	90 Years	All	10	Phase 2	United States
3	NCT00584948	September 2007	16 December 2017	Memantine Treatment in Fragile X-Associated Tremor/Ataxia Syndrome	Characterization and Treatment of CNS Abnormalities in Premutation Carriers: A Double-Blind Placebo-Controlled Trial of Memantine	Fragile X-Associated Tremor/Ataxia Syndrome;Fragile X Premutation Carriers	Drug: Memantine;Drug: Placebo	University of California, Davis	National Institute on Aging (NIA);Forest Laboratories	Not recruiting	30 Years	80 Years	All	94	N/A	United States