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270 / 1,666 drugs found* Show info (disease name, etc.) on mouse-over.
 No.   DrugBank   Drug (Description in trials) 
 [Number of descriptions] 		  KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   7-beta-Hydroxyepiandrosterone  [1] 7-beta-hydroxyepiandrosterone;   -   -   -   [1]
6
 2   ACR325  [1] Acr325;   -   -   -   [1]
6
 3   AV-101  [1] Av-101;   -   -   -   [1]
6
 4   Acamprosate  [1] Acamprosate;   D02780
 D07058 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [2]
6,
206
 5   Acetaminophen  [8] Acetaminophen; Acetaminophen tab 650mg; Acetaminophen tablets; Acetaminophen/paracetamol; Oxycodone/acetaminophen; Paracetamol (acetaminophen); Tramadol /acetaminophen; Tramadol hydrochloride + acetaminophen;   D00217   [2] PTGS1, PTGS2   [21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway   [13]
3,
6,
13,
34,
35,
46,
49,
51,
70,
86,
231,
256,
271
 6   Acetate  [76] 11c acetate; 11c-acetate; 20mg/0.5ml glatiramer acetate; 40 mg glatiramer acetate; [n-trans-3-hexenoyl] human growth hormone releasing factor (1-44) acetate; Abiraterone acetate; Acetate; Bazedoxifene acetate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Caspofungin acetate; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortisone acetate; Cosyntropin acetate; Cyclophosphamide/glatiramer acetate; Delmitide acetate; Depot leuprolide acetate 3.75 mg; Desmopressin acetate; Desmopressin acetate trihydrate; Dirucotide acetate; Experimental glatiramer acetate; Flecainide acetate; Glatiramer acetate; Glatiramer acetate (copaxone®); Glatiramer acetate (db); Glatiramer acetate (ga); Glatiramer acetate (ga) 40 mg; Glatiramer acetate (ol); Glatiramer acetate 150mg enteric coated tablets; Glatiramer acetate 150mg enteric-coated (gastro-resistant) tablets; Glatiramer acetate 20 mg; Glatiramer acetate 20 mg, with mitoxantrone; Glatiramer acetate 20 mg/0.5 ml; Glatiramer acetate 40 mg; Glatiramer acetate injection with oral cetirizine hydrochloride; Glatiramer acetate with minocycline; Glatiramer acetate, (copaxone®); Glatiramer acetate, ifn-beta 1a (im), ifn-beta 1a (subcutaneous), and ifn-beta 1b; Glatiramer acetate, n-acetylcysteine; Gonadorelin acetate and triptorelin acetate; Human interferon beta-1a and glatiramer acetate; Hydrocortisone sodium acetate; L-lysyl-d-prolyl-l-threonine acetate; Lanreotide acetate; Leuprolide acetate (la); Leuprolide acetate 11.25 mg; Leuprolide acetate 3 month depot; Leuprolide acetate 30 mg; Leuprolide acetate 45 mg; Leuprolide acetate depot; Leuprorelin acetate; Leuprorelin acetate 3.75mg injection; Loestrin (norethindrone acetate and ethinyl estradiol); Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol); Luphere depot 3.75mg(leuprolide acetate 3.75mg); Lupron (leuprolide acetate); Macimorelin acetate; Megestrol acetate; Megestrol acetate tablet; Nomegestrol acetate; Phosphate and betamethasone acetate, 2 ml.; Plovamer acetate; Prednisolone acetate; Prednisone acetate; Prednisone acetate tablets; Sodium acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]-phenyl]-acetate; Sotrastaurin (inn) acetate; Tetracosactide acetate; Tocopherol acetate; Tocopheryl acetate; Triptorelin acetate and gonadorelin acetate; Ulipristal acetate; Zinc acetate; Zinc acetate (20mg/d); Zinc acetate dihydrate; Zuretinol acetate;   -   -   -   [40]
1,
2,
6,
10,
13,
35,
40,
46,
49,
51,
60,
64,
70,
71,
73,
75,
76,
78,
81,
83,
85,
86,
88,
90,
96,
97,
113,
145,
156,
162,
171,
206,
222,
224,
225,
235,
265,
288,
298,
299
 7   Acetylcysteine  [8] Acetylcysteine; Acetylcysteine sodium; Glatiramer acetate, n-acetylcysteine; N acetylcysteine; N-acetylcysteine; N-acetylcysteine (nac); N-acetylcysteine capsule; N-acetylcysteine, (nac);   D00221   -   -   [16]
6,
13,
19,
20,
49,
51,
58,
85,
94,
96,
97,
111,
164,
233,
298,
299
 8   Activated charcoal  -  D03251   -   -   [8]
6,
13,
46,
85,
86,
96,
97,
298
 9   Ademetionine  -  D07128   -   -   [15]
6,
14,
22,
43,
44,
46,
47,
49,
50,
60,
84,
93,
96,
97,
172
 10   Agomelatine  [2] Agomelatine; Agomelatine or piacebo;   D02578   [3] HTR2C, MTNR1A, MTNR1B   [6] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse   [1]
6
 11   Allopurinol  [4] Allopurinol; Allopurinol sandoz 100 mg, tabletten; Allopurinol sodium; Azathioprine and allopurinol;   D00224   [1] XDH   [5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism   [6]
6,
46,
57,
66,
96,
97
 12   Altropane  [2] Altropane; Altropane®;   -   -   -   [1]
6
 13   Amantadine  [10] 240mg amantadine hcl er tablets; 320mg amantadine hcl er tablets; Ads-5102 (extended release amantadine hcl); Amantadine; Amantadine 300 mg; Amantadine hcl er; Amantadine hcl extended release; Amantadine hydrochloride; Amantadine sulfate; Pk-merz® 200mg/500ml inj(amantadine) , normal saline 500ml inj;   D00777
 D07441 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [4]
6,
8,
13,
127
 14   Ambroxol  [2] Ambroxol; Ambroxol hydrochloride;   D07442   -   -   [2]
6,
19
 15   Amoxicillin  [7] Amoxicillin; Amoxicillin and tetracycline; Amoxicillin hydrate; Amoxicillin, metronidazole and tetracycline; Clartihromycin, amoxicillin, and omeprazole; Lansoprazole, amoxicillin, clarithromycin; Takecab tablets + amoxicillin + clarithromycin (first-line eradication) takecab tablets + amoxicillin + metronidazole (second-line eradication);   D00229
 D02925
 D07452 		  -   -   [6]
6,
46,
63,
96,
97,
222
 16   Aplindore  [2] Aplindore; Aplindore mr tablets;   -   -   -   [1]
6
 17   Apomorphine  [19] 6abeta - apomorphine-10,11-diol hydrochloride hemihydrate; 6aß - apomorphine-10,11-diol hydrochloride hemihydrate; Apomorphine; Apomorphine 0.25% (2.5mg/ml); Apomorphine hcl injection; Apomorphine hydrochloride; Apomorphine hydrochloride 1.8mg inhalation powder, pre-dispensed; Apomorphine hydrochloride 2.8mg inhalation powder, pre-dispensed; Apomorphine hydrochloride 4.0 mg inhalation powder, pre-dispensed; Apomorphine hydrochloride 5.8 mg inhalation powder, pre-dispensed; Apomorphine hydrocloride; Apomorphine hydrocloride hemihydrate; Apomorphine infusion; Apomorphine nasal powder; Dopaminergic agonist + apomorphine; Injection of apomorphine; Iv apomorphine; S.c. apomorphine; Subcutaneous apomorphine;   D02004
 D07460 		  [2] DRD1, DRD2   [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [1]
6
 18   Aripiprazole  [1] Aripiprazole;   D01164   [4] DRD2, DRD3, HTR1A, HTR2A   [12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway   [2]
6,
206
 19   Armodafinil  [1] Armodafinil;   D03215   [1] SLC6A3   [6] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Synaptic vesicle cycle   [3]
6,
13,
84
 20   Atomoxetine  [1] Atomoxetine;   D02574
 D07473 		  [1] SLC6A2   [1] Synaptic vesicle cycle   [3]
6,
8,
13
 21   Bavisant  [3] Bavisant; Bavisant dihydrochloride monohydrate; Bavisant hydrochloride monohydrate;   D09870   [1] HRH3   [1] Neuroactive ligand-receptor interaction   [1]
6
 22   Benserazide  [8] Benserazide; Benserazide hydrochloride; Levodopa / benserazide 200 + 50 mg; Levodopa 100 mg / benserazide 25 mg; Levodopa benserazide madopar; Levodopa benserazide teva italia; Levodopa/benserazide; Levodopa/benserazide 100/25 mg;   D03082   [1] DDC   [9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [1]
6
 23   Benzofuran  [2] Benzofuran; R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride;   -   -   -   [1]
6
 24   Bifenthrin  -  -   -   -   [2]
6,
46
 25   Botulinum Toxin Type B  [3] Botulinum toxin type b; Botulinum toxin type b (2500 units / vial); Botulinum toxin type b (myobloc);   D02735   [1] SNAP25   [2] Insulin secretion, Synaptic vesicle cycle   [3]
2,
6,
51
 26   Botulinum toxin type A  [3] Botulinum toxin type a; Botulinum toxin type a (nabota®) injection into the gastrocnemius muscle; Clostridium botulinum toxin type a;   D00783   [1] SNAP25   [2] Insulin secretion, Synaptic vesicle cycle   [13]
2,
5,
6,
7,
13,
15,
17,
36,
51,
70,
113,
149,
226
 27   Bromocriptine  [2] Bromocriptine; Bromocriptine and other dopamine agonists;   D00780
 D03165 		  [2] DRD2, PRL   [12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway   [2]
6,
74
 28   Bumetanide  [2] Bumetanide; Bumetanide white, oblong, scored tablet;   D00247   [1] SLC12A2   [3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection   [2]
6,
158
 29   Buspirone  [2] Buspirone; Buspirone hydrochloride;   D00702
 D07593 		  [2] DRD2, HTR1A   [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway   [2]
6,
51
 30   Butylphthalide  [1] Butylphthalide;   -   -   -   [2]
2,
6
 31   CEP-1347  [5] Cep-1347; Cep-1347 10mg; Cep-1347 50mg; Cep1347; Cep1347 25mg;   -   -   -   [1]
6
 32   Cabergoline  [2] Cabergoline; Pasireotide with or without cabergoline;   D00987   [2] DRD2, PRL   [12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway   [3]
6,
74,
75
 33   Caffeine  [5] Caffeine; Caffeine 100 mg; Caffeine 100-200 mg bid; Caffeine alkaloid; Dextromethorphan and caffeine;   D00528
 D01453 		  [11] ADORA1, ADORA2A, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A   [22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [6]
2,
6,
46,
78,
96,
97
 34   Calcium  [25] Amorphous calcium carbonate; Ascal(r) / carbasalate calcium; Atorvastatin calcium; Calcitriol & calcium; Calcium; Calcium and cholecalciferol; Calcium carbonate; Calcium carbonate and alphacalcidol; Calcium channel blockers; Calcium channel blockers (amlodipine, azelnidipine); Calcium citrate; Calcium citrate with vitamin d2; Calcium gluconate; Calcium lactate; Calcium levofolinate; Calcium rosuvastatin; Calcium, dietary; Carbasalate calcium; Crestor tablets (calcium rosuvastatin) film-coated tablets; Crystalline calcium supplements; Ibandronate+alfacalcidol+calcium; Low molecular weight heparin calcium injection; Rosuvastatin calcium; Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin); Vidofludimus calcium;   -   -   -   [24]
6,
13,
19,
46,
49,
51,
65,
68,
75,
79,
84,
93,
94,
95,
96,
97,
214,
215,
222,
224,
235,
265,
298,
299
 35   Cannabidiol  [6] Cannabidiol; Cannabidiol (cbd); Cannabidiol / dronabinol capsule 5 mg+2,5 mg; Cannabidiol capsule 5 mg; Cannabidiol oral solution; Cannabidiol tablet 10 mg;   D10915   [2] CNR1, CNR2   [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis   [14]
2,
6,
13,
46,
95,
96,
97,
140,
144,
145,
157,
158,
193,
271
 36   Capsaicin  [4] Capsaicin; Capsaicin challenge; Capsaicin vapor; Qutenza (8% capsaicin);   D00250   [1] TRPV1   [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction   [6]
2,
6,
19,
86,
113,
226
 37   Carbidopa  [60] Accordion pill carbidopa/levodopa; Accordion pill™ carbidopa/levodopa; Accordion pill™ carbidopa/levodopa 50/400 mg; Accordion pill™ carbidopa/levodopa 50/500 mg; Capsules containing: carbidopa (25 mg), levodopa (100 mg), entacapone (200 mg); Carbidopa; Carbidopa 20 mg; Carbidopa 27.5 mg; Carbidopa 65 mg capsule; Carbidopa and levodopa 25mg/100mg; Carbidopa fu; Carbidopa levodopa; Carbidopa monohydrate; Carbidopa, levodopa, entacapone; Carbidopa- levodopa; Carbidopa-levodopa; Carbidopa/l-dopa; Carbidopa/l-dopa/entacapone; Carbidopa/levodopa; Carbidopa/levodopa, immediate release; Carbidopa/levodopa/entacapone; Comparator: carbidopa; Continuous intrajejunal infusion of levodopa-carbidopa; Controlled-release levodopa / carbidopa; Entacapone and carbidopa; Immediate release carbidopa/levodopa; Immediate release carbidopa/levodopa 25/100 mg; Levodopa and carbidopa; Levodopa and carbidopa sc solution; Levodopa and carbidopa solution for sc administration; Levodopa carbidopa (lc) oral encapsulated immediate release (ir) tablets; Levodopa carbidopa intestinal gel (lcig); Levodopa, carbidopa, entacapone; Levodopa, carbidopa, odm-104; Levodopa-carbidopa; Levodopa-carbidopa (lc) oral encapsulated immediate release (ir) tablets; Levodopa-carbidopa immediate release (lc-ir) tablets; Levodopa-carbidopa intestinal gel; Levodopa-carbidopa multilayer extended release tablet; Levodopa-carbidopa xl tablet (m); Levodopa-carbidopa-entacapone; Levodopa/carbidopa; Levodopa/carbidopa (4:1); Levodopa/carbidopa (sinemet); Levodopa/carbidopa 100/25; Levodopa/carbidopa hydrate; Levodopa/carbidopa solution; Levodopa/carbidopa(200mg/50mg); Levodopa/carbidopa/entacapone; Nd0612 (levodopa/carbidopa solution); Odm-101 105mg carbidopa; Odm-101 65mg carbidopa; Oral levodopa and carbidopa; Oral levodopa/carbidopa; Sinemet (levodopa/carbidopa); Sinemet plus (levodopa/carbidopa); Sinemet® controlled release (carbidopa/levodopa); Stalevo (levodopa/ carbidopa/ entacapone); Stalevo (levodopa/carbidopa/entacapona); Xp21279 and carbidopa (experimental);   D00558   [1] DDC   [9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [8]
2,
4,
6,
13,
17,
90,
164,
201
 38   Carnosine  [3] Carnosine; Carnosine supplementation; Carnosine, capsulle, 2 g/day, 8 weeks;   -   -   -   [2]
6,
13
 39   Carvedilol  [2] Carvedilol; Spironolactone captopril carvedilol;   D00255
 D03415 		  [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2   [12] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [4]
6,
57,
86,
113
 40   Ceftriaxone  [1] Ceftriaxone;   D00924
 D07659 		  -   -   [3]
2,
6,
97
 41   Chloride ion  -  -   -   -   [17]
6,
11,
13,
14,
34,
46,
51,
96,
97,
127,
168,
193,
227,
228,
288,
297,
299
 42   Chloroxylenol  -  D03473   -   -   [4]
6,
13,
46,
168
 43   Cholecalciferol  [9] 5000 iu of cholecalciferol; Calcium and cholecalciferol; Cholecalciferol; Cholecalciferol (vitamin d3); Cholecalciferol 10,000 iu; Cholecalciferol 400 iu; Cholecalciferol and c. xanthorrhiza; Cholecalciferol concentrate; Cholecalciferol, vitamin d3;   D00188   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [15]
6,
13,
19,
20,
34,
46,
49,
53,
60,
65,
96,
97,
228,
298,
299
 44   Clarithromycin  [6] Biaxin ( clarithromycin); Clarithromycin; Lansoprazole, amoxicillin, clarithromycin; Lansoprazole, clarithromycin, amoxycillin; Rifabutin, clarithromycin, and clofazimine; Takecab tablets + amoxicillin + clarithromycin (first-line eradication) takecab tablets + amoxicillin + metronidazole (second-line eradication);   D00276   -   -   [8]
6,
63,
84,
96,
97,
222,
228,
299
 45   Clonazepam  [1] Clonazepam;   D00280   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
6
 46   Clonidine  [3] Clonidine; Clonidine hcl cf 0,150 mg, tabletten; Clonidine hydrochloride;   D00281
 D00604 		  [3] ADRA2A, ADRA2B, ADRA2C   [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway   [2]
6,
78
 47   Clozapine  [1] Clozapine;   D00283   [11] ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E   [8] Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway   [1]
6
 48   Cobalt chloride  -  -   -   -   [1]
6
 49   Cocoa  [3] Cocoa; Dark chocolate (85% cocoa); White chocolate (0% cocoa);   -   -   -   [1]
6
 50   Creatine  [4] Creatine; Creatine monohydrate; Creatine-13c; Pyruvate, creatine, niacinamide;   -   -   -   [12]
1,
2,
5,
6,
8,
13,
46,
49,
50,
113,
156,
201
 51   Cyanocobalamin  -  D00166
 D03615
 D03616
 D03617 		  -   -   [12]
6,
13,
49,
62,
86,
96,
97,
201,
229,
254,
284,
299
 52   D-Serine  [2] D-serine; D-serine (~2g/day);   -   -   -   [1]
6
 53   D-glucose  [3] 2-deoxy-2 [f-18] fluoro-2-d-glucose; [18f]fluoro-2-deoxy-2-d-glucose; D-glucose;   D00009   -   -   [6]
6,
13,
49,
86,
88,
299
 54   Darifenacin  [2] Darifenacin; Oxybutynin and darifenacin;   D01699
 D03654 		  [1] CHRM3   [9] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction   [2]
6,
13
 55   Date  [1] Date;   -   -   -   [3]
6,
88,
113
 56   Deanol  [2] Deanol; Deanol pyroglutamate;   D07777   -   -   [1]
6
 57   Deferiprone  [7] Deferiprone; Deferiprone (ferriprox); Deferiprone 600 mg delayed release tablet; Deferiprone 80 mg/ml oral solution; Deferiprone 80 mg/ml oral solution (ferriprox); Deferiprone oral solution; Ferrprox (deferiprone);   D07416   -   -   [5]
2,
6,
120,
122,
233
 58   Desmopressin  [7] Ddavp (desmopressin); Desmopressin; Desmopressin acetat; Desmopressin acetate; Desmopressin acetate trihydrate; Desmopressin intranasal; Desmopressin oral melt;   D00291
 D02235 		  [2] AVPR2, F8   [4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption   [6]
6,
64,
72,
75,
225,
288
 59   Dexmedetomidine  [8] Dexmedetomidine; Dexmedetomidine 1; Dexmedetomidine 2; Dexmedetomidine 3; Dexmedetomidine and fentanyl; Dexmedetomidine group; Dexmedetomidine hydrochloride; Dexmedetomidine hydrochloride infusion;   D00514
 D01205 		  [3] ADRA2A, ADRA2B, ADRA2C   [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway   [11]
2,
4,
6,
21,
34,
70,
113,
212,
215,
226,
280
 60   Dextromethorphan  [9] Dextromethorphan; Dextromethorphan 30 mg; Dextromethorphan and caffeine; Dextromethorphan hbr and quinidine sulfate; Dextromethorphan hydrobromide; Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg; Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg; Dextromethorphan/quinidine 20mg/10mg (dm/q 20mg/10mg); Dimebon + dextromethorphan;   D00848
 D03742
 D03744 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [9]
2,
6,
8,
13,
46,
78,
96,
97,
156
 61   Dihydrotachysterol  -  D00299   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [1]
6
 62   Dipivefrin  [1] Dipivefrin;   D02349   [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3   [13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
6
 63   Dipraglurant  [1] Dipraglurant;   -   -   -   [1]
6
 64   Doconexent  -  -   -   -   [7]
6,
49,
90,
94,
240,
299,
301
 65   Domperidone  [3] Domperidone; Domperidone (drug); Levodopa and domperidone;   D01745
 D07868 		  [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [5]
6,
13,
17,
51,
230
 66   Donepezil  [4] Donepezil; Donepezil hci (drug); Donepezil hydrochloride; Donepezil sandoz;   D00670
 D07869 		  [1] ACHE   [2] Cholinergic synapse, Glycerophospholipid metabolism   [9]
5,
6,
13,
46,
78,
124,
127,
156,
206
 67   Dopamine  [9] Bromocriptine and other dopamine agonists; Cerebral dopamine neurotrophic factor; Continuous release dopamine agonists; Dopamine; Dopamine agent; Dopamine agonist treatment; Dopamine agonists; Dopamine agonists (pramipexole, ropirinole); Recombinant human cerebral dopamine neurotrophic factor;   D00633
 D07870 		  [5] DRD1, DRD2, DRD3, DRD4, DRD5   [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [3]
6,
7,
74
 68   Doxepin  [2] Doxepin; Doxepin and zopiclone;   D00814
 D07875 		  [3] HRH1, SLC6A2, SLC6A4   [5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle   [1]
6
 69   Droxidopa  [1] Droxidopa;   D01277   [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3   [13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [3]
5,
6,
17
 70   Duloxetine  [3] Duloxetine; Duloxetine hydrochloride; Duloxetine hydrochloride (hci);   D01179
 D07880 		  [2] SLC6A2, SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
6,
13,
49
 71   Eliprodil  [1] Eliprodil;   -   -   -   [1]
6
 72   Eltoprazine  [3] Eltoprazine; Eltoprazine hcl; Eltoprazine hydrochloride;   -   -   -   [1]
6
 73   Entacapone  [12] Capsules containing: carbidopa (25 mg), levodopa (100 mg), entacapone (200 mg); Carbidopa, levodopa, entacapone; Carbidopa/l-dopa/entacapone; Carbidopa/levodopa/entacapone; Entacapone; Entacapone and carbidopa; Levodopa, carbidopa, entacapone; Levodopa-carbidopa-entacapone; Levodopa/carbidopa/entacapone; Over-encapsulated entacapone tablets; Stalevo (levodopa/ carbidopa/ entacapone); V1512 and entacapone;   D00781   [1] COMT   [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism   [2]
6,
17
 74   Epigallocatechin gallate  [2] Coconut oil and epigallocatechin gallate; Epigallocatechin gallate;   -   -   -   [8]
6,
13,
17,
28,
85,
113,
206,
299
 75   Epinephrine  [4] Bupivacaine/epinephrine/dexamethasone; Epinephrine; Lap tap bupivacaine/epinephrine; Us tap bupivacaine/epinephrine;   D00095
 D00996
 D02149 		  [9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3   [13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [9]
6,
13,
46,
86,
96,
168,
226,
231,
256
 76   Ergoloid mesylate  -  D02268   [6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
6
 77   Erythromycin  [2] Erythromycin; Oral erythromycin;   D00140
 D00851
 D01361
 D02009
 D02184
 D02523
 D02524
 D02525
 D04054 		  -   -   [5]
6,
36,
164,
228,
291
 78   Erythropoietin  [4] Erythropoietin; Erythropoietin human recombinant (eporh); Recombinant human erythropoietin; Recombinant human erythropoietin(rhepo);   D03231   [1] EPOR   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [9]
2,
6,
13,
22,
46,
47,
70,
95,
96
 79   Escitalopram  [3] Escitalopram; Escitalopram oxalate antidepressant; Oral escitalopram;   D02567
 D07704
 D07913 		  [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
2,
6,
13
 80   Esomeprazole  [3] Esomeprazole; Esomeprazole 20 mg; Nexium (esomeprazole magnesium);   D01984
 D04056
 D07917
 D09339 		  [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [6]
6,
46,
86,
98,
298,
299
 81   Eszopiclone  [1] Eszopiclone;   D02624   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [3]
6,
13,
46
 82   Exametazime  [2] Exametazime; Technetium (99mtc) exametazime;   D01109   -   -   [1]
6
 83   Exenatide  [3] Exenatide; Exenatide 10 micrograms; Exenatide 5 micrograms;   D04121   [1] GLP1R   [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [3]
6,
193,
233
 84   Famotidine  [2] Famotidine; Famotidine 20 mg;   D00318   [1] HRH2   [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction   [3]
6,
46,
86
 85   Febuxostat  [1] Febuxostat;   D01206   [1] XDH   [5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism   [3]
2,
6,
13
 86   Fesoterodine  [1] Fesoterodine;   D07226   [2] CHRM2, CHRM3   [11] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway   [1]
6
 87   Filgrastim  [6] Ep2006 (filgrastim); Filgrastim; Filgrastim (g-csf); Filgrastim hexal; Filgrastim, alemtuzumab; Granulocyte colony-stimulating factor (filgrastim);   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [28]
2,
6,
13,
16,
25,
26,
28,
34,
35,
36,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
85,
96,
113,
164,
283,
284,
285,
331
 88   Finasteride  [1] Finasteride;   D00321   [1] SRD5A2   [2] Prostate cancer, Steroid hormone biosynthesis   [1]
6
 89   Fipamezole  [7] Fipamezole; Fipamezole hydrochloride; Fipamezole hydrochloride 30 mg oral disintegrating tablets; Fipamezole hydrochloride 60 mg oral disintegrating tablets; Fipamezole hydrochloride 90 mg oral disintegrating tablets; Fipamezole odt; Fipamezole odt cohort 2;   -   -   -   [2]
6,
17
 90   Flecainide  [2] Flecainide; Flecainide acetate;   D00638
 D07962 		  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [1]
6
 91   Florbenazine F-18  -  -   -   -   [1]
6
 92   Fludeoxyglucose F-18  [1] Fludeoxyglucose f 18;   -   -   -   [8]
6,
13,
34,
46,
53,
84,
127,
300
 93   Fludrocortisone  [1] Fludrocortisone;   D00986
 D07967 		  [1] NR3C2   [1] Aldosterone-regulated sodium reabsorption   [3]
6,
17,
81
 94   Flumazenil  [4] 11c-flumazenil; [11c]flumazenil; Flumazenil; Pet with 11c-flumazenil;   D00697   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [5]
6,
13,
17,
18,
206
 95   Flutemetamol  [2] Flutemetamol; Vizamyl (flutemetamol(f-18));   -   -   -   [5]
5,
6,
7,
17,
127
 96   Folic acid  [5] Folic acid; Folic acid or folate; Folic acid, vitamin b6, vitamin b12; Methotrexate and folic acid; Rituximab, mtx, folic acid;   D00070   -   -   [11]
6,
13,
46,
49,
62,
84,
86,
96,
97,
254,
284
 97   Foliglurax  [1] Foliglurax;   -   -   -   [1]
6
 98   Fursultiamine  [1] Fursultiamine;   D03319   -   -   [1]
6
 99   GPI-1485  [1] Gpi 1485;   -   -   -   [1]
6
 100   Gabapentin  [3] Gabapentin; Gabapentin prescriptions; Transdermal fentanyl matrix, gabapentin;   D00332   [5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1   [9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy (DCM), GABAergic synapse, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle   [7]
6,
13,
19,
70,
97,
226,
298
 101   Galantamine  [2] Galantamine; Galantamine hydrobromide;   D02173
 D04292 		  [1] ACHE   [2] Cholinergic synapse, Glycerophospholipid metabolism   [2]
6,
127
 102   Ginkgo biloba  [2] Ginkgo biloba; Ginkgo biloba pills sig: 300mg/tid;   -   -   -   [3]
6,
13,
90
 103   Glutathione  [10] Glutathione; Glutathione sodium; Gsh (glutathione); Inhaled reduced glutathione; Intranasal glutathione - (in)gsh; Oral glutathione; Oral reduced l-glutathione; Reduced glutathione; Reduced glutathione 100mg; Reduced glutathione 200mg;   D00014
 D00031 		  -   -   [2]
6,
299
 104   Glycerin  -  D00028   -   -   [6]
6,
13,
53,
265,
316,
317
 105   Glycerol phenylbutyrate  [1] Glycerol phenylbutyrate;   D10127   -   -   [2]
6,
251
 106   Glycopyrronium  -  D00540
 D10938 		  [1] CHRM3   [9] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction   [1]
6
 107   Gold  [3] Gold; Gold nanocrystals; Sodium aurothiomalate (intramuscular gold);   -   -   -   [5]
2,
6,
13,
46,
171
 108   Grapefruit  [2] Grapefruit; Grapefruit juice;   -   -   -   [5]
6,
46,
50,
83,
97
 109   Green tea leaf  [1] Green tea leaf;   D06903   -   -   [5]
6,
17,
28,
46,
96
 110   Heptaminol  [2] Heptaminol; Heptaminol hydrochloride;   D07158   -   -   [1]
6
 111   Hydrocortisone  [22] Combination oral budesonide and rectal hydrocortisone; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortef (hydrocortisone); Dual release hydrocortisone (plenadren); Hydrocortisone; Hydrocortisone (solucortef); Hydrocortisone 10mg tablet; Hydrocortisone 20mg tablets; Hydrocortisone cream; Hydrocortisone cream 1%; Hydrocortisone cream 10mg/g fna fagron; Hydrocortisone efcortesol & solu-cortef; Hydrocortisone modified release capsules; Hydrocortisone roussel; Hydrocortisone sodium acetate; Hydrocortisone sodium phosphate; Hydrocortisone sodium succinate; Hydrocortisone takeda, tabletter; Mesalazine with hydrocortisone sodium succinate; Solu-cortef (hydrocortisone); Subcutaneous hydrocortisone; Subcutaneous hydrocortisone 10mg;   D00088   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [8]
6,
53,
75,
78,
81,
83,
97,
299
 112   Hydrocortisone acetate  -  D00165   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [8]
6,
53,
75,
78,
81,
83,
97,
299
 113   Hydrocortisone succinate  -  D01442   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
6,
81,
83
 114   Hydrogen  [2] Hydrogen; Tch346 (dibenz[b,f]oxepin-10-ylmethyl-prop-2-ynyl-amine, hydrogen maleate salt);   -   -   -   [5]
5,
6,
17,
97,
226
 115   ITI-214  [1] Iti-214;   -   -   -   [1]
6
 116   Idebenone  [2] Idebenone; Idebenone 150 mg film-coated tablets;   D01750   -   -   [4]
6,
13,
113,
302
 117   Inosine  [2] 1) inosine 5'-monophosphate; Inosine;   D00054   -   -   [4]
2,
6,
13,
17
 118   Iodide I-123  -  -   -   -   [2]
2,
6
 119   Ioflupane I-123  [1] Ioflupane i 123;   D10014   -   -   [3]
2,
5,
6
 120   Ipratropium  [4] Ipratropium; Ipratropium bromide (drug); Nebulized combination ipratropium bromide with salbutamol; Nebulized ipratropium bromide;   D02212   [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   [11] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway   [2]
6,
86
 121   Iproniazid  [1] Iproniazid;   D02579   [2] MAOA, MAOB   [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [1]
6
 122   Isoflurane  [1] Isoflurane;   D00545   -   -   [1]
6
 123   Isoxaflutole  -  -   -   -   [8]
5,
6,
13,
18,
81,
113,
149,
299
 124   Isradipine  [5] Dynacirc cr (isradipine); Isradipine; Isradipine cr 10mg; Isradipine cr 20mg; Isradipine cr 5mg;   D00349   [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   [34] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
6
 125   Istradefylline  [8] Istradefylline; Istradefylline ( kw-6002); Istradefylline (kw-6002); Istradefylline 20 mg; Istradefylline 20 mg or 40 mg; Istradefylline 40 mg; Kw-6002 (istradefylline); Rifampin 300mg bid + istradefylline 40mg day 8 only;   D04641   [1] ADORA2A   [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway   [1]
6
 126   Ketamine  [3] Ketamine; S-ketamine; S-ketamine & midazolam;   D00711
 D08098 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [6]
6,
13,
70,
113,
156,
215
 127   L-Cysteine  -  D00026
 D02326 		  -   -   [9]
6,
13,
19,
84,
85,
88,
90,
254,
296
 128   L-Leucine  [1] L-leucine;   D00030   -   -   [7]
5,
6,
7,
127,
283,
284,
299
 129   L-Tryptophan  -  D00020   -   -   [1]
6
 130   Lactobacillus plantarum  [3] Lactobacillus plantarum; Lactobacillus plantarum ps128; Probiotic-lactobacillus plantarum ps128;   -   -   -   [2]
6,
156
 131   Lactose  [3] Lactose; Lactose in water; Lactose monohydrate;   D00046
 D03226 		  -   -   [6]
2,
6,
13,
97,
228,
310
 132   Lenomorelin  -  -   -   -   [3]
6,
78,
299
 133   Leptin  [3] Hu leptin (a-100); Human recombinant leptin (metreleptin); Leptin;   -   -   -   [2]
6,
265
 134   Levetiracetam  [1] Levetiracetam;   D00709   [1] SV2A   [1] ECM-receptor interaction   [4]
2,
4,
6,
13
 135   Levodopa  [87] Accordion pill carbidopa/levodopa; Accordion pill™ carbidopa/levodopa; Accordion pill™ carbidopa/levodopa 50/400 mg; Accordion pill™ carbidopa/levodopa 50/500 mg; Capsules containing: carbidopa (25 mg), levodopa (100 mg), entacapone (200 mg); Carbidopa and levodopa 25mg/100mg; Carbidopa levodopa; Carbidopa, levodopa, entacapone; Carbidopa- levodopa; Carbidopa-levodopa; Carbidopa/levodopa; Carbidopa/levodopa, immediate release; Carbidopa/levodopa/entacapone; Comparator: levodopa; Continuous intrajejunal infusion of levodopa-carbidopa; Controlled-release levodopa / carbidopa; Immediate release carbidopa/levodopa; Immediate release carbidopa/levodopa 25/100 mg; Intravenous levodopa; Iv levodopa; Levodopa; Levodopa (delivered intravenously); Levodopa (drug), intraduodenal administration; Levodopa (l-dopa); Levodopa (l-dopa) + standard care; Levodopa / benserazid; Levodopa / benserazide 200 + 50 mg; Levodopa 100 mg / benserazide 25 mg; Levodopa 100 mg a cap; Levodopa 125 mg a cap; Levodopa 150 mg a cap; Levodopa 25mg/100mg; Levodopa 75 mg a cap; Levodopa acute challenge; Levodopa and carbidopa; Levodopa and carbidopa sc solution; Levodopa and carbidopa solution for sc administration; Levodopa and decarboxylase inhibitor; Levodopa and domperidone; Levodopa benserazide madopar; Levodopa benserazide teva italia; Levodopa carbidopa (lc) oral encapsulated immediate release (ir) tablets; Levodopa carbidopa intestinal gel (lcig); Levodopa cr (controlled release); Levodopa cyclops; Levodopa dc.it fu; Levodopa dispersible; Levodopa infusion; Levodopa mr; Levodopa powder for inhalation; Levodopa test; Levodopa, carbidopa, entacapone; Levodopa, carbidopa, odm-104; Levodopa, decarboxylase inhibitor and comt inhibitor; Levodopa-carbidopa; Levodopa-carbidopa (lc) oral encapsulated immediate release (ir) tablets; Levodopa-carbidopa immediate release (lc-ir) tablets; Levodopa-carbidopa intestinal gel; Levodopa-carbidopa multilayer extended release tablet; Levodopa-carbidopa xl tablet (m); Levodopa-carbidopa-entacapone; Levodopa/benserazide; Levodopa/benserazide 100/25 mg; Levodopa/benzeraside; Levodopa/benzerazide; Levodopa/carbidopa; Levodopa/carbidopa (4:1); Levodopa/carbidopa (sinemet); Levodopa/carbidopa 100/25; Levodopa/carbidopa hydrate; Levodopa/carbidopa solution; Levodopa/carbidopa(200mg/50mg); Levodopa/carbidopa/entacapone; Levodopa/ddci; Nacom levodopa+cardidopa; Nd0612 (levodopa/carbidopa solution); Oral levodopa and carbidopa; Oral levodopa/carbidopa; Rasagiline mesylate with levodopa; Safinamide + levodopa; Sinemet (levodopa/carbidopa); Sinemet plus (levodopa/carbidopa); Sinemet® controlled release (carbidopa/levodopa); Stalevo (levodopa/ carbidopa/ entacapone); Stalevo (levodopa/carbidopa/entacapona); Tvp-1012 (1 mg/day) with levodopa; Tvp-1012 1mg with levodopa;   D00059   [5] DRD1, DRD2, DRD3, DRD4, DRD5   [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [7]
2,
4,
6,
17,
90,
164,
201
 136   Levomefolic acid  -  D09353   -   -   [1]
6
 137   Liatermin  [2] Liatermin; Liatermin (r-methugdnf);   D04727   -   -   [1]
6
 138   Lidocaine  [8] 5% lidocaine/5 mg/ml estradiol compound cream; Alkalinized lidocaine-heparin; Bladder instillation with heparin/ lidocaine; Lidocaine; Lidocaine injection 2%; Lidocaine patch 5%; Lidocaine releasing intravesical system - liris®; Local anesthesia (lidocaine hydrochloride);   D00358
 D02086
 D08127 		  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [10]
6,
13,
46,
84,
86,
97,
168,
226,
231,
256
 139   Liraglutide  [1] Liraglutide;   D06404   [1] GLP1R   [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [3]
6,
75,
193
 140   Lisuride  [5] Lisuride; Lisuride hydrogenmaleate; Lisuride transdermal system; Lisuride tts 10cm²; Lisuride tts 20cm²;   D01462
 D08132 		  [3] DRD2, DRD3, DRD4   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [2]
6,
86
 141   Lixisenatide  [1] Lixisenatide;   D09729   [1] GLP1R   [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [1]
6
 142   Loratadine  [1] Loratadine;   D00364   [1] HRH1   [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction   [3]
6,
13,
46
 143   Lovastatin  [5] Lovastatin; Lovastatin 60 mg; Lovastatin ™; Lovastatin, then minocycline/lovastatin; Minocycline, then minocycline/lovastatin;   D00359   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [10]
6,
34,
46,
79,
156,
160,
195,
206,
263,
310
 144   Lubiprostone  [1] Lubiprostone;   D04790   [1] CLCN2   [1] Mineral absorption   [4]
6,
13,
290,
299
 145   Magnesium  [16] (s)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide; (s)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide; Magnesium; Magnesium citrate; Magnesium gluconate; Magnesium hydroxide; Magnesium oxide; Magnesium sulfate; Mineral boost (magnesium); Nexium (esomeprazole magnesium); Omeprazole magnesium; Saroglitazar magnesium 2 mg; Saroglitazar magnesium 4 mg; Sodium picosulfate, magnesium oxide and citric acid; Sodium picosulfate/magnesium citrate laxative; Sulfate, magnesium;   -   -   -   [15]
6,
11,
13,
46,
64,
93,
97,
166,
225,
235,
284,
291,
296,
297,
298
 146   Magnesium oxide  [2] Magnesium oxide; Sodium picosulfate, magnesium oxide and citric acid;   D01167   -   -   [3]
6,
166,
291
 147   Maltodextrin  [3] Maltodextrin; Maltodextrin fiber supplement; Resistant maltodextrin;   D02329   -   -   [4]
6,
13,
96,
97
 148   Mannitol  [7] Dp mannitol; Idpm: inhaled dry powder mannitol; Inhaled dry powder mannitol; Inhaled mannitol; Mannitol; Mannitol + pulmozyme; Mannitol inhalation powder;   D00062   -   -   [3]
6,
96,
299
 149   Masitinib  [10] Masitinib; Masitinib (3.0); Masitinib (4.5); Masitinib (6.0); Masitinib (ab1010); Masitinib 100mg; Masitinib 200mg; Masitinib 3 mg; Masitinib 6.0 mg; Masitinib mesylate;   D10229   [1] KIT   [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway   [6]
2,
5,
6,
13,
46,
96
 150   Medical Cannabis  -  -   -   -   [6]
2,
6,
13,
90,
96,
97
 151   Melatonin  [10] 3 mg melatonin; 5 mg melatonin; Circadin ( inn= melatonin); Diazepam, melatonin; Dtr melatonin (nih cc pds); Hourly dosing of the nychtemeral secretion of melatonin; Melatonin; Melatonin cr; Melatonin pr; Melatonin(circadin®);   D08170   [2] MTNR1A, MTNR1B   [2] Circadian entrainment, Neuroactive ligand-receptor interaction   [8]
6,
13,
46,
49,
90,
97,
144,
202
 152   Melevodopa  [2] Melevodopa; Melevodopa and decarboxylase inhibitor;   D07304   -   -   [1]
6
 153   Melperone  [2] Melperone; Melperone hcl;   D07309   [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [1]
6
 154   Memantine  [3] Memantine; Memantine (ebixa); Memantine hydrochloride;   D04905
 D08174 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [7]
2,
6,
8,
13,
49,
127,
205
 155   Metformin  [12] 750 mg metformin and 7.5 g l-citrulline daily p.o.; Glucophage (metformin); L-citrulline and metformin & l-citrulline; Metformin; Metformin (generic); Metformin 500mg; Metformin and metformin & l-citrulline; Metformin hcl; Metformin hydrochloride; Metformin/cp-690,550; Pioglitazone or metformin; Sitagliptin and metformin;   D00944
 D04966 		  [2] PRKAA1, PRKAA2   [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway   [17]
6,
13,
46,
49,
67,
75,
77,
81,
86,
113,
158,
206,
225,
233,
265,
285,
299
 156   Methylphenidate  [11] D-methylphenidate; Methylphenidate; Methylphenidate (mpd); Methylphenidate (overencapsulated); Methylphenidate 10mg tablets; Methylphenidate hydrochloride; Methylphenidate modified release; Methylphenidate modified release 20 mg; Methylphenidate modified release 30 mg; Methylphenidate modified release 40 mg; Methylphenidate, fluoxetin, risperidone;   D01296
 D04999 		  [2] SLC6A2, SLC6A3   [6] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Synaptic vesicle cycle   [7]
6,
13,
34,
84,
113,
179,
206
 157   Midazolam  [6] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Midazolam; Midazolam 2 mg; Midazolam 3 mg; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142; S-ketamine & midazolam;   D00550
 D00696
 D05028 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [10]
2,
3,
6,
13,
46,
70,
96,
97,
231,
298
 158   Midodrine  [2] Midodrine; Midodrine hydrochloride;   D01307
 D08220 		  [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [3]
6,
17,
58
 159   Minocycline  [7] Combination of minocycline and mtx or mtx alone; Glatiramer acetate with minocycline; Lovastatin, then minocycline/lovastatin; Minocycline; Minocycline 100 mg film-coated tablets; Minocycline hydrochloride; Minocycline, then minocycline/lovastatin;   D00850
 D05045 		  -   -   [14]
2,
6,
8,
13,
46,
84,
85,
90,
94,
162,
201,
206,
280,
299
 160   Minodronic acid  [1] Minodronic acid;   -   -   -   [4]
6,
46,
93,
95
 161   Mirabegron  [1] Mirabegron;   D09535   [1] ADRB3   [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway   [3]
6,
13,
226
 162   Moclobemide  [1] Moclobemide;   D02561   [1] MAOA   [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [1]
6
 163   Modafinil  [4] Modafinil; Modafinil 50mg; Over-encapsulated modafinil; Provigil (modafinil);   D01832   -   -   [4]
6,
13,
49,
93
 164   Moxifloxacin  [5] Avelox- moxifloxacin; Moxifloxacin; Moxifloxacin 400 mg; Moxifloxacin hydrochloride; Moxifloxacin infusion;   D00874
 D08237 		  -   -   [8]
2,
6,
46,
49,
85,
86,
240,
299
 165   Muscimol  [1] Muscimol;   -   -   -   [1]
6
 166   Nabilone  [3] Cesamet™ (nabilone); Nabilone; Nabilone 0.25 mg;   D05099   [2] CNR1, CNR2   [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis   [2]
6,
13
 167   Nalmefene  [1] Nalmefene;   D05111   [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [1]
6
 168   Naloxone  [8] Naloxone; Naloxone hydrochloride; Oxycodone naloxone prolonged release tablets; Oxycodone/naloxone prolonged release t; Oxycodone/naloxone prolonged release tablets; Oxycodone/naloxone prolonged release tablets 10/5 mg; Oxycodone/naloxone prolonged release tablets 20/10 mg; Oxycodone/naloxone prolonged release tablets 5/2.5 mg;   D01340
 D08249 		  [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [2]
6,
226
 169   Naltrexone  [5] 4.5 mg naltrexone; Low dose naltrexone; Naltrexone; Naltrexone hydrochloride; Naltrexone-hcl;   D02095
 D05113 		  [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [11]
6,
10,
13,
40,
41,
42,
43,
44,
45,
96,
97
 170   Nebicapone  [1] Nebicapone;   -   -   -   [1]
6
 171   Nelotanserin  [1] Nelotanserin;   D09645   [1] HTR2A   [5] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse   [1]
6
 172   Neridronic Acid  [1] Neridronic acid;   -   -   -   [1]
6
 173   Niacin  [5] Dose-establishing study 1 niacin 250mg; Dose-establishing study 1 niacin 500mg; Dose-establishing study 2 niacin 500mg; Niacin; Niacin first;   D00049   -   -   [4]
6,
78,
79,
265
 174   Nicotinamide  [2] Nicotinamide; Nicotinamide riboside;   D00036   -   -   [8]
5,
6,
13,
46,
49,
53,
67,
162
 175   Nicotinamide riboside  [1] Nicotinamide riboside;   -   -   -   [1]
6
 176   Nicotine  [6] Nicotine; Nicotine gum; Nicotine nasal spray 10 mg/ml (0.5 mg/spray); Nicotine patch; Nicotine transdermal patch; Transdermal nicotine;   D03365
 D05156
 D05157 		  [16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG   [5] Calcium signaling pathway, Chemical carcinogenesis, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction   [2]
6,
84
 177   Nilotinib  [8] Cohort 1:nilotinib oral capsules (150mg or 300mg); Cohort 2: nilotinib oral capsules (dose to be determined from cohort 1); Nilotinib; Nilotinib (tasigna); Nilotinib 150 mg; Nilotinib 150mg oral capsule [tasigna]; Nilotinib 300mg oral capsule [tasigna]; Nilotinib hydrochloride monohydrate;   D08953   [4] ABL1, KIT, PDGFRA, PDGFRB   [33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [5]
6,
8,
34,
51,
86
 178   Nitrogen  [1] Nitrogen;   D00083   -   -   [5]
5,
6,
17,
211,
299
 179   Nortriptyline  [1] Nortriptyline;   D00816
 D08288 		  [2] SLC6A2, SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [2]
6,
226
 180   Omeprazole  [16] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Clartihromycin, amoxicillin, and omeprazole; Diclofenac + omeprazole; Dimebon + omeprazole; Naproxen 500 mg tablets (pn 200 minus omeprazole); Omeprazole; Omeprazole (uk licensed generic product); Omeprazole 20 mg; Omeprazole 20mg; Omeprazole 20mg bid; Omeprazole 40 mg; Omeprazole 40mg capsule; Omeprazole magnesium; Omeprazole rectally 1mg/kg; Pn 200 tablets (500 mg naproxen and 20 mg omeprazole); Rifaximin+omeprazole+miralax;   D00455
 D01207
 D05259
 D05261 		  [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [15]
6,
8,
13,
46,
51,
85,
96,
97,
98,
225,
271,
282,
294,
298,
299
 181   Opicapone  [2] Opicapone; Opicapone (opc);   D10825   [1] COMT   [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism   [1]
6
 182   Oxybuprocaine  [1] Oxybuprocaine;   D01768
 D08319 		  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [1]
6
 183   Oxybutynin  [3] Oxybutynin; Oxybutynin and darifenacin; Oxybutynin hydrochloride;   D00465
 D00722 		  [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   [11] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway   [1]
6
 184   Oxycodone  [14] Extended-release oxycodone; Oxycodone; Oxycodone by patient-controlled analgesia (pca); Oxycodone depot ”sandoz”, depot tablets; Oxycodone hydrochloride; Oxycodone naloxone prolonged release tablets; Oxycodone orion; Oxycodone/acetaminophen; Oxycodone/naloxone prolonged release t; Oxycodone/naloxone prolonged release tablets; Oxycodone/naloxone prolonged release tablets 10/5 mg; Oxycodone/naloxone prolonged release tablets 20/10 mg; Oxycodone/naloxone prolonged release tablets 5/2.5 mg; Pr oxycodone;   D03783
 D05312
 D05462 		  [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [7]
6,
13,
46,
70,
226,
231,
298
 185   Oxygen  [9] Continuous oxygen; Helium / oxygen mixed gas inhalation therapy; Medical air vs oxygen; Medical grade oxygen; Nitric oxide plus oxygen; Oxygen; Oxygen 40 %; Oxygen supplementation; Perfluorinated gas/oxygen mixture;   D00003   -   -   [18]
5,
6,
17,
46,
49,
70,
84,
85,
86,
88,
90,
96,
97,
193,
211,
226,
299,
330
 186   Pardoprunox  [2] Pardoprunox; Pardoprunox hydrochloride;   D09397   [3] DRD2, DRD3, HTR1A   [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway   [1]
6
 187   Paroxetine  [3] Paroxetine; Paroxetine & prednisolone; Paroxetine hydrochloride 10 & 20 mg and prednisolone 1 mg bp;   D02260
 D02362
 D05374
 D05375 		  [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
6,
13,
46
 188   Perampanel  [3] 2 mg perampanel; 4 mg perampanel; Perampanel;   D08964   [4] GRIA1, GRIA2, GRIA3, GRIA4   [13] Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Transcriptional misregulation in cancer, cAMP signaling pathway   [3]
2,
6,
144
 189   Pergolide  [1] Pergolide;   D00502
 D08339 		  [2] DRD1, DRD2   [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [1]
6
 190   Phenelzine  -  D00505
 D08349 		  [2] MAOA, MAOB   [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [1]
6
 191   Phenylbutyric acid  -  D05868   -   -   [10]
2,
3,
6,
8,
93,
94,
244,
251,
297,
299
 192   Piclozotan  [1] Piclozotan;   -   -   -   [1]
6
 193   Pilocarpine  [2] Pilocarpine; Pilocarpine nitrate 5%;   D00525
 D02200
 D05478 		  [2] CHRM2, CHRM3   [11] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway   [3]
6,
53,
299
 194   Pimavanserin  [5] Active drug: pimavanserin 17mg (2 strength tablets); Pimavanserin; Pimavanserin (acp-103); Pimavanserin tartrate; Pimavanserin tartrate (acp-103);   -   -   -   [1]
6
 195   Pioglitazone  [6] Actos (pioglitazone); Pioglitazone; Pioglitazone 15 mg; Pioglitazone and tretinoin; Pioglitazone or metformin; Tretinoin and pioglitazone hcl;   D00945
 D08378 		  [1] PPARG   [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer   [17]
2,
6,
13,
15,
20,
46,
49,
65,
67,
78,
81,
86,
96,
229,
265,
298,
299
 196   Piribedil  [2] Piribedil; Piribedil (clarium);   D07305   [2] DRD2, DRD3   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [1]
6
 197   Pitolisant  [2] Bf2.649 (pitolisant); Pitolisant;   D10749   [1] HRH3   [1] Neuroactive ligand-receptor interaction   [1]
6
 198   Pittsburgh Compound B  [2] Pittsburgh compound b; Pittsburgh compound b (c-11 pib);   -   -   -   [2]
6,
127
 199   Pramipexole  [20] Dopamine agonists (pramipexole, ropirinole); Mirapex (pramipexole); P2b001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),; P2b001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),; Pramipexole; Pramipexole 0.125 mg tablets; Pramipexole 0.5 mg tablets; Pramipexole dihydrochloride; Pramipexole dihydrochloride extended-release tablets; Pramipexole dihydrochloride monohydrate; Pramipexole dihydrochloride monohydrate extended release; Pramipexole er; Pramipexole extended release; Pramipexole extended release tablet; Pramipexole immediate release; Pramipexole immediate release tablet; Pramipexole ir; Pramipexole or ropinirole; Pramipexole sr; R(+) pramipexole dihydrochloride monohydrate;   D00559
 D05575 		  [3] DRD2, DRD3, DRD4   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [2]
2,
6
 200   Preladenant  [4] Preladenant; Preladenant 10 mg tablet; Preladenant 2 mg tablet; Preladenant 5 mg tablet;   D09717   [1] ADORA2A   [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway   [1]
6
 201   Pridopidine  [2] Pridopidine; Pridopidine (90 mg);   D09953   [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [2]
6,
8
 202   Propofol  [3] Intubated with propofol (ip); Propofol; Propofol-lipuro;   D00549   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [8]
6,
21,
22,
34,
46,
84,
98,
296
 203   Propranolol  [5] Atenolol or propranolol; Losartan and atenolol or propranolol; Propranolol; Propranolol hcl cf 40 mg tablet; Propranolol treatment;   D00483
 D08443 		  [3] ADRB1, ADRB2, ADRB3   [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
6,
158,
167,
227,
278
 204   Pyridostigmine  [2] Pyridostigmine; Pyridostigmine bromide;   D00487   [1] ACHE   [2] Cholinergic synapse, Glycerophospholipid metabolism   [4]
3,
6,
11,
256
 205   Pyridoxine  [4] Pyridoxine; Pyridoxine 10mg; Pyridoxine 10mg bp; Pyridoxine plus prednisolone;   D02179
 D08454 		  -   -   [4]
6,
49,
93,
145
 206   Quetiapine  [2] Extended-release quetiapine fumarate; Quetiapine;   D00458
 D08456 		  [2] DRD2, HTR2A   [11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway   [2]
6,
13
 207   Raclopride  [2] 11c-raclopride; Raclopride;   -   -   -   [4]
5,
6,
7,
17
 208   Ramelteon  [1] Ramelteon;   D02689   [2] MTNR1A, MTNR1B   [2] Circadian entrainment, Neuroactive ligand-receptor interaction   [3]
6,
8,
46
 209   Rasagiline  [16] 1.0 mg rasagiline mesylate; Group r rasagiline; Group r+ad rasagiline + antidepressant; P2b001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),; P2b001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),; Rasagiline; Rasagiline 1 mg capsule; Rasagiline 1mg tablet; Rasagiline 2 mg tablet; Rasagiline mesilate; Rasagiline mesylate; Rasagiline mesylate 1.0 mg; Rasagiline mesylate plus mirapex; Rasagiline mesylate with levodopa; Rasagiline mesylate with requip; Rasagiline tablets;   D02562
 D08469
 D10829 		  [1] MAOB   [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [4]
2,
5,
6,
17
 210   Remifentanil  [1] Remifentanil;   D01177
 D08473 		  [1] OPRM1   [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction   [2]
6,
70
 211   Repaglinide  [2] Repaglinide; Repaglinide and insulin;   D00594   [2] ABCC8, KCNJ11   [4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus   [2]
6,
299
 212   Reynoutria multiflora root  -  -   -   -   [1]
6
 213   Rifampicin  [1] Rifampicin;   D00211   -   -   [7]
6,
13,
17,
46,
84,
86,
299
 214   Rifaximin  [9] Rifaximin; Rifaximin 550 mg; Rifaximin delayed release (dr); Rifaximin delayed release 400 mg film coated tablet; Rifaximin delayed release tablets; Rifaximin eir; Rifaximin oral tablet; Rifaximin+omeprazole+miralax; Rifaximin-eir;   D02554   -   -   [7]
6,
65,
94,
96,
97,
99,
296
 215   Rivastigmine  [5] Exelon patch (rivastigmine transdermal system); Rivastigmine; Rivastigmine capsule; Rivastigmine patch 9.5 cm2; Rivastigmine transdermal patch;   D02558
 D03822 		  [1] ACHE   [2] Cholinergic synapse, Glycerophospholipid metabolism   [3]
5,
6,
13
 216   Ropinirole  [27] Hp-3000 (ropinirole hydrochloride patch); Hp-3000(ropinirole hydrochloride patch); Pramipexole or ropinirole; Ropinirole; Ropinirole (as hydrochloride); Ropinirole controlled-release (requip cr) for rls; Ropinirole cr 2mg tablet; Ropinirole cr 8mg tablet; Ropinirole hydrochloride; Ropinirole hydrochloride extended-release tablet; Ropinirole hydrochloride extended-release tablet placebo; Ropinirole hydrochloride prolonged release; Ropinirole immediate release; Ropinirole implant; Ropinirole ir; Ropinirole ir tablets; Ropinirole monotherapy; Ropinirole oral product; Ropinirole pr; Ropinirole pr, 2mg; Ropinirole pr/xr; Ropinirole pr/xr tablets; Ropinirole prolonged release; Ropinirole prolonged release/extended release(pr/xr); Ropinirole xl; Ropinirole xl (formerly cr); Ropinirole/l-dopa;   D00784
 D08489 		  [3] DRD2, DRD3, DRD4   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [3]
6,
74,
309
 217   Rosuvastatin  [6] Calcium rosuvastatin; Crestor tablets (calcium rosuvastatin) film-coated tablets; Rosuvastatin; Rosuvastatin 10 mg; Rosuvastatin 20mg; Rosuvastatin calcium;   D01915
 D08492 		  [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [8]
6,
46,
49,
51,
79,
96,
271,
299
 218   Rotigotine  [10] Rotigotine; Rotigotine (reference product pr 2.1.1); Rotigotine (test product pr 2.3.1); Rotigotine hydrochloride; Rotigotine nasal spray; Rotigotine transdermal patch; Rotigotine transdermal patch 2mg/24h(10cm2); Rotigotine transdermal patch 4mg/24h (20cm2); Rotigotine transdermal patch 6mg/24h (30cm2); Rotigotine transdermal patch 8mg/24h (40cm2);   D05768   [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [1]
6
 219   Safinamide  [9] Safinamide; Safinamide + levodopa; Safinamide metansolfonato (12 weeks); Safinamide methanesulfonate; Safinamide methanesulfonate 100mg; Safinamide methanesulfonate 150mg; Safinamide methansulfonate; Safinamide, mao-b inhibitor; Xadago (safinamide);   D10158   [1] MAOB   [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [2]
6,
17
 220   Sage  [4] Sage; Sage leaf; Sage-217; Sage-718;   -   -   -   [2]
6,
8
 221   Saracatinib  [1] Saracatinib;   D09664   [2] ABL1, SRC   [45] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection   [2]
6,
89
 222   Sarcosine  [2] Sarcosine; Sarcosine capsule;   -   -   -   [1]
6
 223   Sargramostim  [3] Gm-csf (granulocyte-macrophage colony-stimulating factor, sargramostim); Sargramostim; Sargramostim (leukine);   D05803   [1] CSF2RA   [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer   [6]
6,
28,
60,
62,
96,
229
 224   Sarizotan  [4] Sarizotan; Sarizotan hc1; Sarizotan hcl; Sarizotan hydrochloride;   -   -   -   [2]
6,
156
 225   Selegiline  [3] Orally disintegrating selegiline (zelapar); Selegiline; Selegiline hcl 5 pch;   D00785
 D03731 		  [1] MAOB   [13] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism   [1]
6
 226   Semaglutide  [1] Semaglutide;   D10025   [1] GLP1R   [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [1]
6
 227   Serine  [4] D-serine; D-serine (~2g/day); L-serine; Serine;   D00016   -   -   [3]
2,
6,
86
 228   Sertraline  [1] Sertraline;   D00825
 D02360 		  [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
6,
8,
206
 229   Sevoflurane  [3] Intubated with sevoflurane (is); Sevoflurane; Sevoflurane anesthetics;   D00547   -   -   [5]
6,
21,
22,
98,
296
 230   Sildenafil  [25] 20 mg sildenafil citrate by mouth; 5% sildenafil cream; Access program - sildenafil citrate, viagra, revatio; Acute (1 hour) sildenafil; Bosentan and sildenafil; Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); Oral sildenafil; Sildenafil; Sildenafil (50 mg); Sildenafil (as citrate); Sildenafil (revatio); Sildenafil (revatio) 20 mg tid; Sildenafil 20 mg tablets; Sildenafil 20mg; Sildenafil 20mg and bosentan 62.5mg; Sildenafil 40mg oral capsule; Sildenafil and losartan; Sildenafil citrate; Sildenafil citrate (uk-92,480); Sildenafil singly or in association with bosentan; Sildenafil therapy; Sitaxsentan and sildenafil; Sodium tanshinone iia sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth; Sub-chronic (4 weeks) sildenafil; Tadalafil and sildenafil;   D02229
 D08514 		  [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [16]
6,
46,
50,
51,
85,
86,
96,
113,
210,
211,
212,
225,
226,
278,
294,
299
 231   Silodosin  [1] Silodosin;   D01965   [1] ADRA1A   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [2]
6,
13
 232   Simvastatin  [11] Encapsulated simvastatin tablets; Ezetimibe+simvastatin drug combination; Simvastatin; Simvastatin 20mg/5ml oral suspension; Simvastatin 40 mg film-coated tablets; Simvastatin 40mg; Simvastatin alternova; Simvastatin susp.; Simvastatin treatment for 28 days; Simvastatin-ratiopharm; Simvastatin-ratiopharm®;   D00434   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [19]
6,
13,
15,
34,
46,
49,
51,
66,
79,
86,
89,
94,
158,
162,
195,
265,
298,
299,
310
 233   Smilagenin  [1] Smilagenin;   -   -   -   [1]
6
 234   Sodium chloride  [14] 0.9% sodium chloride; 0.9% sodium chloride (normal saline); 0.9% sodium chloride injection; 0.9% w/v sodium chloride solution; Isotonic sodium chloride solution; Physiological serum (sodium chloride); Sodium chloride; Sodium chloride (7%); Sodium chloride 0,9%; Sodium chloride 6%; Sodium chloride solution; Sodium chloride solution 0.9%; Sodium chloride solvent; Sodium pyruvate in 0.9% sodium chloride solution;   D02056   -   -   [19]
6,
11,
13,
14,
17,
34,
46,
51,
53,
67,
78,
86,
97,
168,
193,
227,
228,
288,
299
 235   Sodium oxybate  [1] Sodium oxybate;   D05866   -   -   [3]
6,
120,
149
 236   Solifenacin  [2] Solifenacin; Solifenacin succinate (vesicare);   D01269
 D08522 		  [1] CHRM3   [9] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction   [1]
6
 237   Sulfate ion  -  -   -   -   [22]
2,
6,
11,
13,
26,
34,
36,
46,
49,
60,
61,
64,
66,
79,
86,
96,
222,
226,
265,
296,
297,
299
 238   Sumanirole  [1] Sumanirole;   -   -   -   [1]
6
 239   Suvorexant  [1] Suvorexant;   D10082   [2] HCRTR1, HCRTR2   [1] Neuroactive ligand-receptor interaction   [3]
5,
6,
13
 240   Tadalafil  [11] Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); Fdc macitentan/tadalafil; Tadalafil; Tadalafil 20 mg; Tadalafil 20 mg film-coated tablets; Tadalafil 40 mg; Tadalafil and ambrisentan upfront combination therapy; Tadalafil and sildenafil; Tadalafil oral suspension; Tadalafil, placebo; Tadalafil- tablet or oral suspension;   D02008   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [6]
6,
51,
75,
84,
86,
113
 241   Talampanel  [1] Talampanel;   D02696   [4] GRIA1, GRIA2, GRIA3, GRIA4   [13] Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Transcriptional misregulation in cancer, cAMP signaling pathway   [2]
2,
6
 242   Tavapadon  -  D11431   [2] DRD1, DRD5   [10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway   [1]
6
 243   Technetium Tc-99m exametazime  -  D02284   -   -   [1]
6
 244   Terazosin  [2] Terazosin; Terazosin 5 mg;   D00610
 D08569 		  [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
6
 245   Tesofensine  [3] 1. tesofensine (ns 2330); Tesofensine; Tesofensine/metoprolol;   -   -   -   [2]
6,
193
 246   Tolcapone  [1] Tolcapone;   D00786   [1] COMT   [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism   [3]
6,
28,
127
 247   Topiramate  [2] Topiramate; Topiramate (drug);   D00537   [36] CA2, CA4, CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [48] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [5]
6,
140,
144,
156,
193
 248   Topramezone  -  -   -   -   [7]
6,
13,
46,
50,
96,
97,
299
 249   Tozadenant  [5] Tozadenant; Tozadenant (syn115) 120 mg bid; Tozadenant (syn115) 180 mg bid; Tozadenant (syn115) 240 mg bid; Tozadenant (syn115) 60 mg bid;   D10174   [1] ADORA2A   [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway   [1]
6
 250   Triamcinolone  [10] Bladder instillation with triamcinolone acetonide; Bladder instillation without triamcinolone acetonide; Bupivacaine & triamcinolone acetonide; Intra plexus triamcinolone and bupivicaine injection; Triamcinolone; Triamcinolone acetonide; Triamcinolone acetonide and normal saline solution; Triamcinolone hexacetonid (lederspan); Triamcinolone hexacetonide; Triamcinolone hexacetonide (lederspan);   D00385
 D00983
 D00984
 D00985
 D06216 		  [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [18]
6,
10,
13,
35,
40,
41,
42,
43,
44,
45,
46,
56,
70,
90,
96,
97,
226,
298
 251   Trihexyphenidyl  [2] Primary cervical dystonia (trihexyphenidyl); Trihexyphenidyl;   D00787
 D08638 		  [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   [11] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway   [2]
5,
6
 252   Trimethobenzamide  [2] Trimethobenzamide; Trimethobenzamide hydrochloride;   D02733
 D08643 		  -   -   [1]
6
 253   Tropicamide  [5] 0 mg tropicamide; 0.3 mg tropicamide; 1 mg tropicamide; 3 mg tropicamide; Tropicamide;   D00397   [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   [11] Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway   [2]
6,
19
 254   Tyrosine  [2] L-tyrosine; Tyrosine;   D00022   -   -   [3]
6,
86,
111
 255   Ubidecarenone  -  D01065   -   -   [12]
2,
5,
6,
8,
10,
46,
57,
86,
113,
193,
214,
215
 256   Ubiquinol  [1] Ubiquinol;   -   -   -   [3]
6,
8,
17
 257   Uric acid  -  -   -   -   [1]
6
 258   Ursodeoxycholic acid  [9] Udca (ursodeoxycholic acid); Ursodeoxycholic acid; Ursodeoxycholic acid (udca); Ursodeoxycholic acid (urso); Ursodeoxycholic acid 300mg capsule; Ursodeoxycholic acid 300mg tablet; Ursodeoxycholic acid capsules; Ursodeoxycholic acid combination of immunosuppressive agents; Ursodiol (ursodeoxycholic acid, udca);   D00734   [1] NR1H4   [1] Bile secretion   [12]
6,
8,
20,
67,
84,
93,
94,
95,
96,
97,
234,
299
 259   Valerian  [1] Valerian;   -   -   -   [1]
6
 260   Varenicline  [2] Varenicline; Varenicline tartrate;   D08669   [2] CHRNA4, CHRNB2   [3] Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction   [2]
6,
18
 261   Venlafaxine  [3] Efexor xl 75 mg (venlafaxine); Venlafaxine; Venlafaxine hydrochloride;   D00821
 D08670 		  [2] SLC6A2, SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
6,
13,
46
 262   Vitamin E  [8] Coenzyme q10 with vitamin e; Omega-3 and vitamin e supplementation; Vitamin c 10mg/kg vitamin e 10 mg/kg; Vitamin e; Vitamin e - tgps; Vitamin e 800iu; Vitamin e supplement; Vitamin e/selenium;   D02331   -   -   [12]
2,
6,
13,
20,
46,
49,
90,
96,
97,
206,
299,
317
 263   Warfarin  [4] S-warfarin; The generic name is warfarin and many producers will be involved; Warfarin; Warfarin 10 mg;   D00564
 D01280
 D08682 		  [2] NQO1, VKORC1   [5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis   [10]
6,
8,
13,
19,
46,
49,
66,
85,
88,
96
 264   Water  [13] 15 o water; 15-o labeled water; 5% glucose water solution; Dextrose, 5% in water; High water intake; Lactose in water; Pl 12185/0002 & pl 12185/0005(water for injection); Pseudoephedrine + 480 ml water; Pseudoephedrine + 50 ml water; Water; Water for injection; Water for injections; Water for injections, ep;   D00001   -   -   [22]
2,
5,
6,
13,
17,
19,
28,
35,
46,
53,
57,
63,
65,
67,
78,
84,
97,
193,
226,
271,
278,
299
 265   Zoledronic acid  [4] Lonafarnib, zoledronic acid, and pravastatin; Zoledronic acid; Zoledronic acid 5mg/bag 100ml inj; Zoledronic acid monohydrate;   D01968
 D06378
 D06379
 D08689 		  [1] FDPS   [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis   [11]
6,
13,
46,
65,
93,
95,
96,
271,
274,
299,
333
 266   Zolmitriptan  [1] Zolmitriptan;   D00415   [2] HTR1B, HTR1D   [4] Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway   [1]
6
 267   Zolpidem  [4] Zolpidem; Zolpidem first dose; Zolpidem second dose; Zolpidem tartrate;   D00706
 D08690 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [2]
5,
6
 268   Zonisamide  [2] Ad-810n (zonisamide); Zonisamide;   D00538   [8] CACNA1G, CACNA1H, CACNA1I, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [11] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus   [1]
6
 269   Zopiclone  [2] Doxepin and zopiclone; Zopiclone;   D01372   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
6
 270   gamma-Hydroxybutyric acid  -  -   -   -   [3]
6,
120,
149

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