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50 / 1,666 drugs found* Show info (disease name, etc.) on mouse-over.
 No.   DrugBank   Drug (Description in trials) 
 [Number of descriptions] 		  KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   ACR-16  [5] Acr16; Acr16 10 mg; Acr16 22.5 mg; Acr16 45 mg; Acr16 hydrochloride, asp2314 hydrochloride, fr310826;   -   -   -   [1]
8
 2   Alprazolam  [1] Alprazolam;   D00225   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
8
 3   Amantadine  [10] 240mg amantadine hcl er tablets; 320mg amantadine hcl er tablets; Ads-5102 (extended release amantadine hcl); Amantadine; Amantadine 300 mg; Amantadine hcl er; Amantadine hcl extended release; Amantadine hydrochloride; Amantadine sulfate; Pk-merz® 200mg/500ml inj(amantadine) , normal saline 500ml inj;   D00777
 D07441 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [4]
6,
8,
13,
127
 4   Atomoxetine  [1] Atomoxetine;   D02574
 D07473 		  [1] SLC6A2   [1] Synaptic vesicle cycle   [3]
6,
8,
13
 5   Bevantolol  [2] Bevantolol; Bevantolol hydrochloride;   -   -   -   [1]
8
 6   Bupropion  [2] Bupropion; Wellbutrin (bupropion);   D00817
 D07591
 D07938 		  [2] SLC6A2, SLC6A3   [6] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Synaptic vesicle cycle   [2]
8,
96
 7   Citalopram  [2] 20mg daily citalopram; Citalopram;   D00822
 D07704 		  [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
8,
46,
127
 8   Creatine  [4] Creatine; Creatine monohydrate; Creatine-13c; Pyruvate, creatine, niacinamide;   -   -   -   [12]
1,
2,
5,
6,
8,
13,
46,
49,
50,
113,
156,
201
 9   Cysteamine  [9] Cystagon (cysteamine bitartrate) immediate-release capsules; Cystagon® (cysteamine bitartrate); Cysteamine; Cysteamine (mercaptamine) viscous solution; Cysteamine bitartrate; Cysteamine bitartrate (cystagon); Cysteamine bitartrate (inn: mercaptamine bitartrate ); Cysteamine bitartrate delayed-release capsules (rp103); Cysteamine hydrochloride;   D03634
 D03635 		  -   -   [4]
8,
19,
21,
299
 10   Dextromethorphan  [9] Dextromethorphan; Dextromethorphan 30 mg; Dextromethorphan and caffeine; Dextromethorphan hbr and quinidine sulfate; Dextromethorphan hydrobromide; Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg; Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg; Dextromethorphan/quinidine 20mg/10mg (dm/q 20mg/10mg); Dimebon + dextromethorphan;   D00848
 D03742
 D03744 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [9]
2,
6,
8,
13,
46,
78,
96,
97,
156
 11   Digoxin  [3] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Digoxin; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142;   D00298   [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4   [18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
8,
46
 12   Fenofibrate  [2] Fenofibrate; Fenofibrate (insoluble drug delivery-micro particle fenofibrate (idd-p);   D00565   [1] PPARA   [7] Adipocytokine signaling pathway, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease (NAFLD), PPAR signaling pathway, cAMP signaling pathway   [5]
8,
79,
93,
94,
265
 13   GSK-356278  [1] Gsk356278;   -   -   -   [1]
8
 14   Haloperidol  [1] Haloperidol;   D00136
 D01898 		  [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [1]
8
 15   Icosapent ethyl  -  D01892   -   -   [1]
8
 16   Ketoconazole  [2] Dimebon + ketoconazole; Ketoconazole;   D00351   [1] CYP17A1   [6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis   [3]
8,
13,
75
 17   LAX-101  [1] Lax-101;   -   -   -   [1]
8
 18   Laquinimod  [8] Laquinimod; Laquinimod 0.6; Laquinimod 1.2; Laquinimod capsules 0.3 mg; Laquinimod capsules 0.6 mg; Laquinimod cápsulas 0.5 mg; Laquinimod sodium (usan); Laquinimod tablets 0.3 mg;   -   -   -   [4]
8,
13,
49,
96
 19   Latrepirdine  [2] Dimebon (latrepirdine); Latrepirdine;   D09917   [6] ACHE, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [19] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [1]
8
 20   Lithium carbonate  [1] Lithium carbonate;   D00801   -   -   [8]
2,
5,
7,
8,
13,
17,
19,
127
 21   Lithium citrate  -  D04749   -   -   [4]
2,
5,
7,
8
 22   Memantine  [3] Memantine; Memantine (ebixa); Memantine hydrochloride;   D04905
 D08174 		  [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [7]
2,
6,
8,
13,
49,
127,
205
 23   Minocycline  [7] Combination of minocycline and mtx or mtx alone; Glatiramer acetate with minocycline; Lovastatin, then minocycline/lovastatin; Minocycline; Minocycline 100 mg film-coated tablets; Minocycline hydrochloride; Minocycline, then minocycline/lovastatin;   D00850
 D05045 		  -   -   [14]
2,
6,
8,
13,
46,
84,
85,
90,
94,
162,
201,
206,
280,
299
 24   Neflamapimod  [1] Neflamapimod;   D10959   [4] MAPK11, MAPK12, MAPK13, MAPK14   [53] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis (ALS), C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Dopaminergic synapse, Endocrine resistance, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pertussis, Platelet activation, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection   [1]
8
 25   Nilotinib  [8] Cohort 1:nilotinib oral capsules (150mg or 300mg); Cohort 2: nilotinib oral capsules (dose to be determined from cohort 1); Nilotinib; Nilotinib (tasigna); Nilotinib 150 mg; Nilotinib 150mg oral capsule [tasigna]; Nilotinib 300mg oral capsule [tasigna]; Nilotinib hydrochloride monohydrate;   D08953   [4] ABL1, KIT, PDGFRA, PDGFRB   [33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Shigellosis, Viral myocarditis   [5]
6,
8,
34,
51,
86
 26   Olanzapine  [1] Olanzapine;   D00454
 D06623 		  [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6   [16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
2,
8
 27   Omeprazole  [16] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Clartihromycin, amoxicillin, and omeprazole; Diclofenac + omeprazole; Dimebon + omeprazole; Naproxen 500 mg tablets (pn 200 minus omeprazole); Omeprazole; Omeprazole (uk licensed generic product); Omeprazole 20 mg; Omeprazole 20mg; Omeprazole 20mg bid; Omeprazole 40 mg; Omeprazole 40mg capsule; Omeprazole magnesium; Omeprazole rectally 1mg/kg; Pn 200 tablets (500 mg naproxen and 20 mg omeprazole); Rifaximin+omeprazole+miralax;   D00455
 D01207
 D05259
 D05261 		  [2] ATP4A, ATP4B   [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation   [15]
6,
8,
13,
46,
51,
85,
96,
97,
98,
225,
271,
282,
294,
298,
299
 28   Pepinemab  -  D11469   [1] SEMA4D   [1] Axon guidance   [2]
8,
13
 29   Phenylbutyric acid  -  D05868   -   -   [10]
2,
3,
6,
8,
93,
94,
244,
251,
297,
299
 30   Phosphorus  [1] Phosphorus;   -   -   -   [1]
8
 31   Pridopidine  [2] Pridopidine; Pridopidine (90 mg);   D09953   [1] DRD2   [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway   [2]
6,
8
 32   Quinidine  [5] Dextromethorphan hbr and quinidine sulfate; Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg; Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg; Dextromethorphan/quinidine 20mg/10mg (dm/q 20mg/10mg); Quinidine;   D00642
 D00643
 D02272
 D08458 		  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A   [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction   [3]
2,
8,
13
 33   Ramelteon  [1] Ramelteon;   D02689   [2] MTNR1A, MTNR1B   [2] Circadian entrainment, Neuroactive ligand-receptor interaction   [3]
6,
8,
46
 34   Resveratrol  [1] Resveratrol;   -   -   -   [3]
8,
89,
113
 35   Rilmenidine  [1] Rilmenidine;   D08482   [3] ADRA2A, ADRA2B, ADRA2C   [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway   [1]
8
 36   Riluzole  [5] Riluzole; Riluzole 50 mg; Riluzole 50 mg (part b); Riluzole oral soluble film; Riluzole oral soluble film (rosf) 50 mg;   D00775   [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway   [7]
2,
3,
5,
8,
13,
17,
206
 37   Risperidone  [2] Methylphenidate, fluoxetin, risperidone; Risperidone;   D00426   [2] DRD2, HTR2A   [11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway   [5]
8,
156,
179,
187,
206
 38   Rolipram  [1] Rolipram;   D01783   [4] PDE4A, PDE4B, PDE4C, PDE4D   [5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway   [2]
8,
13
 39   Sage  [4] Sage; Sage leaf; Sage-217; Sage-718;   -   -   -   [2]
6,
8
 40   Selisistat  [1] Selisistat;   -   -   -   [1]
8
 41   Sertraline  [1] Sertraline;   D00825
 D02360 		  [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
6,
8,
206
 42   Tetrabenazine  [2] Tetrabenazine; Tetrabenazine withdrawal;   D08575   [1] SLC18A2   [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle   [1]
8
 43   Triheptanoin  [4] Triheptanoin; Triheptanoin 1g/kg/day; Triheptanoin oil; Ux007 (triheptanoin);   D11465   -   -   [10]
2,
8,
120,
149,
156,
248,
256,
257,
317,
324
 44   Ubidecarenone  -  D01065   -   -   [12]
2,
5,
6,
8,
10,
46,
57,
86,
113,
193,
214,
215
 45   Ubiquinol  [1] Ubiquinol;   -   -   -   [3]
6,
8,
17
 46   Ursadiol  -  -   -   -   [6]
8,
20,
93,
97,
234,
299
 47   Ursodeoxycholic acid  [9] Udca (ursodeoxycholic acid); Ursodeoxycholic acid; Ursodeoxycholic acid (udca); Ursodeoxycholic acid (urso); Ursodeoxycholic acid 300mg capsule; Ursodeoxycholic acid 300mg tablet; Ursodeoxycholic acid capsules; Ursodeoxycholic acid combination of immunosuppressive agents; Ursodiol (ursodeoxycholic acid, udca);   D00734   [1] NR1H4   [1] Bile secretion   [12]
6,
8,
20,
67,
84,
93,
94,
95,
96,
97,
234,
299
 48   Valbenazine  [1] Valbenazine;   D10675   [1] SLC18A2   [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle   [1]
8
 49   Valproic Acid  [3] Valproic acid; Valproic acid (vpa); Valproic acid and levocarnitine;   D00399   [7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2   [17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism   [14]
2,
3,
5,
8,
26,
34,
65,
89,
90,
102,
222,
233,
256,
331
 50   Warfarin  [4] S-warfarin; The generic name is warfarin and many producers will be involved; Warfarin; Warfarin 10 mg;   D00564
 D01280
 D08682 		  [2] NQO1, VKORC1   [5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis   [10]
6,
8,
13,
19,
46,
49,
66,
85,
88,
96

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