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 42. Polyarteritis nodosa
 [ 9 clinical trials,    22 drugs(DrugBank: 15 drugs),    23 target genes / 48 target pathways

Searched query = "Polyarteritis nodosa"
The queries were searched in Public_title, Scientific_title, and Condition of the data. Export date: 11/21/2019, 11/20/2019. Trials are sorted by Date_enrolment from most recent to oldest in the table.

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No.TrialIDDate_
enrollement
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Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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Recruitment_
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agemin
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PhaseCountries
1NCT03482479February 4, 201922 October 2019Low Dose Naltrexone to Improve Physical Health in Patients With VasculitisLow Dose Naltrexone to Improve Physical Health in Patients With VasculitisEosinophilic Granulomatosis With Polyangiitis (EGPA);Churg-Strauss Syndrome (CSS);Giant Cell Arteritis;Granulomatosis With Polyangiitis;Microscopic Polyangiitis;Polyarteritis Nodosa;Takayasu ArteritisDrug: Naltrexone Hydrochloride;Other: Placebo ComparatorUniversity of PennsylvaniaRecruiting18 YearsN/AAll60Phase 2United States
2NCT02939573January 201711 November 2019A Randomized Multicenter Study for Isolated Skin VasculitisA Randomized Multicenter Study for Isolated Skin VasculitisPrimary Cutaneous Vasculitis;Cutaneous Polyarteritis Nodosa;IgA Vasculitis;Henoch-Schönlein PurpuraDrug: Colchicine;Drug: Dapsone;Drug: AzathioprineUniversity of PennsylvaniaNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS);National Center for Advancing Translational Science (NCATS);Office of Rare Diseases (ORD)Recruiting18 YearsN/AAll90Phase 2United States;Canada
3EUCTR2013-004668-71-GB25/09/201427 October 2014A study of treatment for polyarteritis nodosa in childrenAn Open Label Randomised Controlled Trial of Mycophenolate Mofetil Versus Cyclophosphamide for the Induction of Remission of Childhood Polyarteritis Nodosa - MYPANChildhood systemic polyarteritis nodosa (PAN)
MedDRA version: 17.0 Level: LLT Classification code 10036026 Term: Polyarteritis nodosa of childhood System Organ Class: 100000004866 ;Therapeutic area: Diseases [C] - Immune System Diseases [C20]
Trade Name: CellCept
Product Name: CellCept (Mycophenolate Mofetil)
Pharmaceutical Form: Powder for oral suspension
INN or Proposed INN: Mycophenolate mofetil
CAS Number: 24280-93-1
Concentration unit: g/ml gram(s)/millilitre
Concentration type: range
Concentration number: 1g-5ml
Trade Name: CellCept
Product Name: CellCept (Mycophenolate Mofetil)
Pharmaceutical Form: Capsule, hard
INN or Proposed INN: Mycophenolate mofetil
CAS Number: 24280-93-1
Concentration unit: mg milligram(s)
Concentration type: not less then
Concentration number: 250-
Trade Name: CellCept (Mycophenolate Mofetil)
Product Name: CellCept (Mycophenolate Mofetil)
Pharmaceutical Form: Film-coated tablet
INN or Proposed INN: Mycophenolate mofetil
CAS Number: 24280-93-1
Concentration unit: mg milligram(s)
Concentration type: not less then
Concentration number: 500-
Trade Name: Cyclophosphamide
Product Name: Cyclophosphamide
Pharmaceutical Form: Powder for solution for injection
University College LondonAuthorisedFemale: yes
Male: yes
40Portugal;Slovenia;Greece;Spain;Turkey;United Kingdom;Italy;Czech Republic;Belgium;Poland;Croatia;Germany;Netherlands;Sweden
4NCT00751517September 200819 February 2015Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing VasculitidesCyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides. A Randomized Controlled Trial.Wegener's Granulomatosis;Churg-Strauss Syndrome;Microscopic Polyangiitis;Polyarteritis NodosaDrug: Methotrexate;Drug: CyclophosphamideUniversity of ParmaNot recruiting18 Years80 YearsBothPhase 2Italy
5NCT00647166May 200819 October 2015Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome)Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Without Poor Prognosis FactorsMPA;PAN or EGPA With FFS=0;At Diagnosis or Within the First 15 Days Following Initiation of CorticosteroidsDrug: corticosteroid and azathioprine;Drug: corticosteroid and placeboAssistance Publique - Hôpitaux de ParisNot recruiting18 YearsN/ABoth114Phase 3France
No.TrialIDDate_
enrollement
Last_Refreshed_
on
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT00307671July 200519 February 2015Treatment of Necrotizing Vasculitides for Patients Older Than 65 YearsTreatment of Necrotizing Vasculitides for Patients Older Than 65 Years Comparison of Two Strategies Combining Steroids With or Without ImmunosuppressantsVasculitis;Wegener's Granulomatosis;Microscopic Polyangiitis;Churg-Strauss Syndrome;Polyarteritis NodosaDrug: prednisone, methylprednisolone,cyclophosphamides;Drug: Cyclophosphamide, Azathioprine,prednisone,methylprednisolone;Drug: Mycophenolate mofetil,methotrexateAssistance Publique - Hôpitaux de ParisNot recruiting65 YearsN/ABoth108Phase 4France
7NCT00006055March 200019 February 2015Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune DiseasesPurpura, Schoenlein-Henoch;Graft Versus Host Disease;Anemia, Hemolytic, Autoimmune;Rheumatoid Arthritis;Churg-Strauss Syndrome;Hypersensitivity Vasculitis;Wegener's Granulomatosis;Systemic Lupus Erythematosus;Giant Cell Arteritis;Pure Red Cell Aplasia;Juvenile Rheumatoid Arthritis;Polyarteritis Nodosa;Autoimmune Thrombocytopenic Purpura;Takayasu ArteritisDrug: anti-thymocyte globulin;Drug: cyclophosphamide;Drug: cyclosporine;Drug: filgrastim;Drug: methylprednisolone;Drug: prednisone;Procedure: Autologous Peripheral Blood Stem Cell TransplantationFairview University Medical CenterNot recruiting1 Year55 YearsBoth10N/AUnited States
8NCT00400075July 199619 February 2015CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis FactorsCHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors a Prospective Randomized Study in 125 PatientsPolyarteritis Nodosa;Microscopic PolyangiitisDrug: azathioprine;Drug: cyclophosphamideHospices Civils de LyonNot recruiting15 Years90 YearsBoth124Phase 4Switzerland
9NCT00001457September 199519 February 2015Lamivudine for Chronic Hepatitis BLamivudine for Chronic Hepatitis BChronic Hepatitis B;Chronic Hepatitis D;Glomerulonephritis;Polyarteritis NodosaDrug: LamivudineNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Not recruitingN/AN/ABoth60Phase 2United States

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