Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 2,4-thiazolidinedione 1件: Thiazolidinedione---1件: 20 💬
2 Acetylcysteine 3件: ACETYLCYSTEINE; Mucomyst; N-Acetylcysteine1件: Acetylcysteine 💬--21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
3 Alemtuzumab 4件: ALEMTUZUMAB; Campath; Lemtrada; MABCAMPATH1件: Alemtuzumab 💬1件: CD52 💬-22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
4 Bezafibrate 1件: BEZAFIBRATE1件: Bezafibrate 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324 💬
5 Biotin 4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: Biotin 💬--5件: 2, 8, 10, 13, 20 💬
6 Busulfan 3件: BUSILVEX; Busulfan; BUSULFANO1件: Busulfan 💬--13件: 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
7 Chenodeoxycholic acid 3件: CDCA; CHENODEOXYCHOLIC ACID; Chenodiol1件: Chenodiol 💬1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 96, 234, 263 💬
8 Cholecalciferol 5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: Cholecalciferol 💬1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
9 Cholic Acid 1件: CHOLIC ACID1件: Cholic acid 💬1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 234, 265, 310 💬
10 Clofarabine 1件: Clofarabine1件: Clofarabine 💬3件: POLA1,
POLA2,
RRM1 💬
7件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 234, 326 💬
11 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan2件: Cyclophosphamide ,
Cyclophosphamide 💬
--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
12 Cyclosporine 10件: CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis1件: Cyclosporine 💬5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
13 Elivaldogene autotemcel 1件: Elivaldogene autotemcel1件: Elivaldogene autotemcel 💬1件: ABCD1 💬2件: ABC transporters, Peroxisome 💬1件: 20 💬
14 Glyceryl Trierucate 1件: Glyceryl Trierucate---1件: 20 💬
15 Glyceryl Trioleate 1件: Glyceryl Trioleate---1件: 20 💬
16 Human interferon beta 3件: Human interferon beta; Interferon beta; Interferon-Beta---6件: 13, 20, 26, 50, 96, 97 💬
17 Hydroxyurea 1件: Hydroxyurea1件: Hydroxyurea 💬1件: RRM2 💬7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284 💬
18 Imidacloprid 0件: ---5件: 19, 20, 125, 234, 326 💬
19 Leriglitazone 1件: Leriglitazone1件: Leriglitazone 💬1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 20 💬
20 Lipoic acid 3件: Alpha Lipoic Acid; Alpha-lipoic acid; Lipoic acid---5件: 2, 5, 13, 14, 20 💬
21 Melphalan 3件: ALKERAN; Melphalan; Melphalan Hydrochloride1件: Melphalan 💬--15件: 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
22 Mycophenolate mofetil 3件: CELLCEPT; Mycophenolate mofetil; Mycophenolate mofetil TEVA1件: Mycophenolate mofetil 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
23 Mycophenolic acid 5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic1件: Mycophenolic acid 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
24 Pioglitazone 1件: Pioglitazone1件: Pioglitazone 💬1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
25 Plerixafor 2件: Mozobil; Plerixafor1件: Plerixafor 💬1件: CXCR4 💬14件: Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬5件: 19, 20, 65, 285, 299 💬
26 Pramipexole 7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL1件: Pramipexole 💬3件: DRD2,
DRD3,
DRD4 💬
8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20 💬
27 Sobetirome 1件: Sobetirome1件: Sobetirome 💬1件: THRB 💬2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20 💬
28 Thalidomide 1件: Thalidomide1件: Thalidomide 💬1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
29 Thiotepa 1件: Thiotepa1件: Thiotepa 💬--12件: 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
30 Ursodeoxycholic acid 4件: UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
31 Vitamin E 2件: Alpha-tocopherol; Vitamin E1件: Vitamin E 💬--12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬