Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Alemtuzumab 💬1件: Alemtuzumab1件: Alemtuzumab--18件: 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
2 Bezafibrate 💬1件: Bezafibrate1件: Bezafibrate1件: NR1C1 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
3 Busulfan 💬1件: Busulfan2件: Busulfan; Busulfano--14件: 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
4 Chenodiol 💬1件: Chenodeoxycholic acid2件: Chenodeoxycholic acid; Chenodiol1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 96, 234, 263 💬
5 Cholecalciferol 💬1件: Cholecalciferol4件: Cholecalciferol; Colecalciferol; Vitamin D-3; Vitamin D31件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬15件: 6, 13, 19, 20, 34, 46, 49, 51, 53, 65, 96, 97, 228, 298, 299 💬
6 Cholic acid 💬1件: Cholic Acid1件: Cholic acid1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 234, 265, 310 💬
7 Clofarabine 💬1件: Clofarabine1件: Clofarabine3件: POLA1,
POLA2,
RRM1 💬 		5件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 96, 234 💬
8 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
9 Cyclophosphamide 💬1件: Cyclophosphamide5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
10 Cyclosporine 💬1件: Cyclosporine6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
11 Dimethyl fumarate 💬1件: Dimethyl fumarate2件: Dimethyl fumarate; Dimethylfumarat1件: KLHL19 💬 6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬6件: 13, 20, 49, 51, 86, 296 💬
12 Elivaldogene autotemcel 💬1件: Elivaldogene autotemcel1件: Elivaldogene autotemcel1件: ABCD1 💬 2件: ABC transporters, Peroxisome 💬1件: 20 💬
13 Hydroxyurea 💬1件: Hydroxyurea1件: Hydroxyurea1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
14 Interferon beta 💬1件: Human interferon beta3件: Human interferon beta; Interferon beta; Interferon-beta2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬3件: 13, 20, 50 💬
15 Leriglitazone 💬1件: Leriglitazone1件: Leriglitazone1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 20 💬
16 Melphalan 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
17 Melphalan hydrochloride 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
18 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
19 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
20 Mycophenolate sodium 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
21 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
22 Pioglitazone 💬1件: Pioglitazone1件: Pioglitazone1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬16件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 220, 229, 265, 298, 299 💬
23 Pioglitazone hydrochloride 💬1件: Pioglitazone1件: Pioglitazone1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬16件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 220, 229, 265, 298, 299 💬
24 Plerixafor 💬1件: Plerixafor1件: Plerixafor1件: CXCR4 💬 14件: Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬4件: 20, 51, 65, 285 💬
25 Pramipexole 💬1件: Pramipexole3件: Pramipexol; Pramipexole; Pramipexole dihydrochloride monohydrate3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 20 💬
26 Pramipexole dihydrochloride 💬1件: Pramipexole3件: Pramipexol; Pramipexole; Pramipexole dihydrochloride monohydrate3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 20 💬
27 Sobetirome 💬1件: Sobetirome1件: Sobetirome1件: THRB 💬 3件: Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20 💬
28 Thalidomide 💬1件: Thalidomide1件: Thalidomide1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300 💬
29 Thioctic acid 💬1件: Lipoic acid1件: Lipoic acid--3件: 13, 14, 20 💬
30 Thiotepa 💬1件: Thiotepa1件: Thiotepa--11件: 13, 28, 46, 51, 60, 65, 85, 96, 107, 284, 285 💬
31 Ursodiol 💬1件: Ursodeoxycholic acid3件: Udca; Ursodeoxycholic acid; Ursodiol1件: NR1H4 💬 1件: Bile secretion 💬13件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
32 Vitamin E 💬1件: Vitamin E2件: Alpha-tocopherol; Vitamin E--6件: 2, 19, 20, 49, 90, 206 💬