Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Amifampridine 2件: Amifampridine; Firdapse1件: Amifampridine 💬 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12 💬
3 Apitegromab 1件: Apitegromab1件: Apitegromab 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
4 Branaplam 1件: BRANAPLAM1件: Branaplam 💬 1件: SMN2 💬 -2件: 3, 8 💬
5 Celecoxib 2件: Celebrex; Celecoxib1件: Celecoxib 💬 1件: PTGS2 💬 22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
6 Dalfampridine 7件: 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra1件: Dalfampridine 💬 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14 💬
7 Hydroxyurea 1件: Hydroxyurea1件: Hydroxyurea 💬 1件: RRM2 💬 7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284 💬
8 Itraconazole 2件: Itraconazole; SPORANOX1件: Itraconazole 💬 --6件: 3, 46, 65, 96, 227, 299 💬
9 Leuprolide 3件: Leuprolide; Leuprolide acetate depot; Leuprorelin---6件: 1, 2, 3, 51, 67, 76 💬
10 Levocarnitine 4件: Carnitine; L-Carnitine; Levocarnitine; Xyzal1件: Levocarnitine 💬 --11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
11 Midazolam 2件: Midazolam; Midazolam injection1件: Midazolam 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
12 Nerve Growth Factor 1件: Nerve Growth Factor---3件: 3, 53, 90 💬
13 Nusinersen 2件: NUSINERSEN; Spinraza1件: Nusinersen 💬 1件: SMN2 💬 -1件: 3 💬
14 Olesoxime 1件: Olesoxime1件: Olesoxime 💬 --3件: 2, 3, 13 💬
15 Onasemnogene abeparvovec 3件: ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma1件: Onasemnogene abeparvovec 💬 1件: SMN1 💬 -1件: 3 💬
16 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬
17 Phosphate ion 1件: Phosphate---32件: 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299 💬
18 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
19 Pyridostigmine 3件: Mestinon; Pyridostigmine; Pyridostigmine Bromide---4件: 3, 6, 11, 256 💬
20 Reldesemtiv 2件: CK-2127107; RELDESEMTIV1件: Reldesemtiv 💬 1件: TNNC2 💬 1件: Calcium signaling pathway 💬2件: 2, 3 💬
21 Riluzole 2件: RILUTEK; Riluzole1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
22 Risdiplam 2件: EVRYSDI; Risdiplam1件: Risdiplam 💬 1件: SMN2 💬 1件: Nucleocytoplasmic transport 💬1件: 3 💬
23 Salbutamol 3件: Albuterol; Salbutamol; Ventolin1件: Albuterol 💬 1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
24 Sesame oil 1件: Sesame oil1件: Sesame oil 💬 --1件: 3 💬
25 Somatotropin 17件: Genotropin; Growth Hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton---25件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337 💬
26 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
27 Talditercept alfa 1件: Taldefgrobep alfa1件: Taldefgrobep alfa 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
28 Testosterone 1件: Testosterone1件: Testosterone 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬8件: 1, 2, 3, 13, 60, 76, 78, 113 💬
29 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: Valproic acid 💬 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬