Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(APAP)		2件: Acetaminophen; Paracetamol1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 AP-101
(AP-101)		1件: AP-101---1件: 2 💬
3 Apabetalone
(Apabetalone)		1件: Apabetalone1件: Apabetalone (Apabetalone) 💬 --1件: 86 💬
4 Apadamtase alfa
(Apadamtase alfa)		2件: Apadamtase alfa; Radamts-132件: Apadamtase alfa (Apadamtase alfa, Apadamtase alfa),
Apadamtase alfa and cinaxadamtase alfa (Apadamtase alfa and cinaxadamtase alfa, Apadamtase alfa) 💬 		1件: ADAMTS13 💬 1件: Platelet activation 💬1件: 64 💬
5 Apelin
(Apelin)		1件: Apelin---1件: 86 💬
6 Apigenin
(Apigenin)		1件: Apigenin---2件: 46, 97 💬
7 Apitegromab
(Apitegromab)		1件: Apitegromab1件: Apitegromab (Apitegromab) 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
8 Apixaban
(apixabanum)		1件: Apixaban1件: Apixaban (Apixaban, APIXABAN) 💬 1件: F10 💬 1件: Complement and coagulation cascades 💬4件: 96, 97, 222, 279 💬
9 Aplindore
(Aplindore)		1件: Aplindore1件: Aplindore fumarate (Aplindore fumarate) 💬 2件: DRD2,
DRD3 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
10 Apomorphine
(Apomorphin)		2件: Apomorphine; Apomorphine hydrochloride2件: Apomorphine hydrochloride (Apomorphine hydrochloride, Apomorphine hydrochloride hydrate, Apokyn, APOKYN, APOMORPHINE HYDROCLORIDE),
Apomorphine (Apomorphine) 💬 		2件: DRD1,
DRD2 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7 💬
11 Apple
(Apple)		0件: ---2件: 58, 70 💬
12 Apraclonidine
(Apraclonidinum)		0件: 2件: Apraclonidine hydrochloride (Apraclonidine hydrochloride, APRACLONIDINE),
Apraclonidine (Apraclonidine) 💬 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 11 💬
13 Apratastat
(Apratastat)		1件: Apratastat1件: Apratastat (Apratastat) 💬 2件: ADAM17,
MMP13 💬 		9件: Alzheimer disease, Coronavirus disease - COVID-19, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway, TNF signaling pathway 💬1件: 46 💬
14 Apremilast
(Apremilast)		1件: Apremilast1件: Apremilast (Apremilast, APREMILAST) 💬 4件: PDE4,
PDE4,
PDE4,
PDE4 💬 		4件: Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
15 Aprotinin
(Aprotinina)		1件: Aprotinin1件: Aprotinin (Aprotinin) 💬 --1件: 28 💬
16 BT200
(PEGylated aptamer targeting Von Willebrand Factor A1 domain)		2件: BT200; Rondoraptivon pegol---1件: 288 💬
17 Bupropion 2件: Bupropion; Bupropion hydrochloride3件: Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide (Aplenzin, APLENZIN) 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬6件: 8, 18, 21, 96, 97, 171 💬
18 Captopril 1件: Captopril1件: Captopril (Apopril) 💬 1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 17, 46, 86, 96, 97, 107, 271 💬
19 CER-001
(Recombinant human apolipoprotein A-I/phospholipid complexes)		1件: CER-001---1件: 79 💬
20 Dalfampridine
(4-AP)		5件: 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine1件: Dalfampridine 💬 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬4件: 3, 4, 13, 14 💬
21 Esuberaprost
(Aps-314d free acid)		1件: Esuberaprost2件: Esuberaprost ,
Esuberaprost sodium 💬 		1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬1件: 86 💬
22 Factor IX Complex (Human)
(APCC)		1件: Prothrombin complex concentrate1件: Factor IX complex 💬 --1件: 288 💬
23 Hydralazine 1件: Hydralazine2件: Hydralazine hydrochloride (Apresoline),
Hydralazine 💬 		1件: AOC3 💬 4件: Glycine, serine and threonine metabolism, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬1件: 67 💬
24 Lorcaserin 1件: Lorcaserin2件: Lorcaserin hydrochloride (APD-356),
Lorcaserin hydrochloride hemihydrate 💬 		1件: HTR2 💬 6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 140 💬
25 Mesalazine 6件: 5-aminosalicylic acid; 5-ASA; Mesalamine; Mesalazina; Mesalazine; Mesalazinum1件: Mesalamine (Apriso, APRISO) 💬 --5件: 46, 96, 97, 98, 164 💬
26 Methylphenidate 2件: Methylphenidate; Methylphenidate hydrochloride2件: Methylphenidate hydrochloride (APTENSIO XR),
Methylphenidate 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206 💬
27 Piperazine 1件: Piperazine5件: Piperazine ,
Piperazine phosphate ,
Piperazine citrate ,
Piperazine adipate (Camin AP),
Piperazine hexahydrate 💬 		--1件: 272 💬
28 Recombinant human alkaline phosphatase
(Human recombinant AP)		0件: 1件: Ilofotase alfa 💬 1件: E3.1.3.1 💬 2件: Folate biosynthesis, Thiamine metabolism 💬1件: 172 💬
29 Royal jelly
(Apis Mellifera Secretion)		1件: Royal jelly1件: Royal jelly 💬 --1件: 49 💬
30 Sildenafil 3件: Sildenafil; Sildenafil citrate; Sildenafilo2件: Sildenafil citrate ,
Sildenafil (Aphrodil) 💬 		1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
31 Skin-derived ABCB5-positive Mesenchymal Stem cells
(ALLO-APZ2-PAOD)		1件: ALLO-APZ2-EB---1件: 36 💬
32 Tipranavir 1件: Tipranavir2件: Tipranavir disodium ,
Tipranavir (Aptivus, APTIVUS) 💬 		--1件: 265 💬
33 Trifluoperazine 1件: Trifluoperazine3件: Trifluoperazine hydrochloride ,
Trifluoperazine maleate ,
Trifluoperazine (Apo-trifluoperazine) 💬 		1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284 💬
34 Trihexyphenidyl 1件: Trihexyphenidyl2件: Trihexyphenidyl hydrochloride ,
Trihexyphenidyl (Apo-trihex) 💬 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6 💬