Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CETP 💬 1件: Cholesterol metabolism Anacetrapib 💬 Anacetrapib 1件: 79 💬
2 PCSK9 💬 1件: Cholesterol metabolism Alirocumab 💬 Alirocumab 1件: 79 💬
3 PCSK9 💬 1件: Cholesterol metabolism Evolocumab 💬 Evolocumab 2件: 79, 222 💬
4 PCSK9 💬 1件: Cholesterol metabolism Inclisiran 💬 Inclisiran 1件: 79 💬
5 ANGPTL3 💬 1件: Cholesterol metabolism Evinacumab 💬 Evinacumab 1件: 79 💬
6 APOC3 💬 2件: PPAR signaling pathway, Cholesterol metabolism Volanesorsen 💬 Volanesorsen 1件: 265 💬
7 LIPA 💬 3件: Steroid biosynthesis, Lysosome, Cholesterol metabolism Sebelipase alfa 💬 Sebelipase alfa 1件: 19 💬
8 SORT1 💬 3件: Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab 2件: 2, 127 💬