Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 NQO1 💬 7件: Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin 💬 Warfarin 11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
2 NCSTN 💬 2件: Notch signaling pathway, Alzheimer disease Tarenflurbil 💬 Tarenflurbil 1件: 13 💬
3 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone 💬 Hydrocortisone 10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
4 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone acetate 💬 Hydrocortisone acetate 1件: 97 💬
5 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone 💬 Betamethasone 8件: 2, 28, 46, 65, 83, 90, 96, 235 💬
6 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Budesonide 💬 Budesonide 9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
7 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
8 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
9 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
10 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
11 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
12 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mifepristone 💬 Mifepristone 1件: 75 💬
13 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Beclomethasone dipropionate 💬 Beclomethasone dipropionate 3件: 85, 97, 98 💬
14 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mometasone furoate 💬 Mometasone furoate 2件: 98, 162 💬
15 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Cortisone acetate 💬 Cortisone acetate 1件: 81 💬
16 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone cypionate 💬 Hydrocortisone cypionate 3件: 6, 81, 83 💬
17 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone acetate 💬 Prednisolone acetate 1件: 222 💬
18 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Clobetasol propionate 💬 Clobetasol propionate 2件: 46, 162 💬
19 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone succinate 💬 Hydrocortisone succinate 3件: 6, 81, 83 💬
20 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Ciclesonide 💬 Ciclesonide 1件: 84 💬
21 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluticasone propionate 💬 Fluticasone propionate 2件: 98, 228 💬
22 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluocinolone acetonide 💬 Fluocinolone acetonide 1件: 90 💬
23 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Deflazacort 💬 Deflazacort 2件: 30, 113 💬
24 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone hemisuccinate 💬 Methylprednisolone hemisuccinate 7件: 13, 49, 50, 51, 53, 97, 211 💬
25 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Halometasone 💬 Halometasone 1件: 162 💬
26 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Clobetasol 💬 Clobetasol 4件: 39, 46, 51, 162 💬
27 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Cortisone 💬 Cortisone 1件: 81 💬
28 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluticasone 💬 Fluticasone 3件: 98, 228, 299 💬
29 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mometasone 💬 Mometasone 2件: 98, 162 💬
30 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone acetate 💬 Prednisone acetate 6件: 35, 41, 46, 49, 162, 224 💬
31 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Vamorolone 💬 Vamorolone 2件: 97, 113 💬
32 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Relacorilant 💬 Relacorilant 1件: 75 💬
33 NPC1L1 💬 1件: Fat digestion and absorption Ezetimibe 💬 Ezetimibe 4件: 49, 79, 93, 260 💬
34 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Spironolactone 💬 Spironolactone 8件: 46, 58, 67, 86, 113, 210, 218, 225 💬
35 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Eplerenone 💬 Eplerenone 4件: 75, 113, 210, 215 💬
36 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Fludrocortisone 💬 Fludrocortisone 3件: 6, 17, 81 💬
37 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Aldosterone 💬 Aldosterone 1件: 222 💬
38 NFE2L2 💬 7件: Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Omaveloxolone 💬 Omaveloxolone 1件: 18 💬
39 NFKB1 💬 76件: Antifolate resistance, MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Cellular senescence, Osteoclast differentiation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Neurotrophin signaling pathway, Prolactin signaling pathway, Adipocytokine signaling pathway, Relaxin signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Pancreatic cancer, Prostate cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
40 NGF 💬 9件: MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels Tanezumab 💬 Tanezumab 2件: 226, 298 💬
41 NGFR 💬 9件: Virion - Lyssavirus, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis - multiple species, Neurotrophin signaling pathway, Transcriptional misregulation in cancer Cenegermin 💬 Cenegermin 2件: 53, 90 💬
42 NPR1 💬 10件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Erythrityl tetranitrate 💬 Erythrityl tetranitrate 1件: 46 💬
43 NPR1 💬 10件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Nesiritide 💬 Nesiritide 2件: 46, 58 💬
44 NPR2 💬 5件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway Erythrityl tetranitrate 💬 Erythrityl tetranitrate 1件: 46 💬
45 NPR2 💬 5件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway Vosoritide 💬 Vosoritide 1件: 276 💬
46 NR1H4 💬 1件: Bile secretion Chenodiol 💬 Chenodeoxycholic acid 4件: 20, 96, 234, 263 💬
47 NR1H4 💬 1件: Bile secretion Ursodiol 💬 Ursodeoxycholic acid 14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
48 NR1H4 💬 1件: Bile secretion Obeticholic acid 💬 Obeticholic acid 3件: 93, 265, 296 💬
49 NR1H4 💬 1件: Bile secretion Cholic acid 💬 Cholic Acid 4件: 20, 234, 265, 310 💬
50 NR1H4 💬 1件: Bile secretion Tropifexor 💬 Tropifexor 1件: 93 💬