Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 13 entries
| No. | KEGG GENES | KEGG PATHWAY | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 |
DHFR
💬1. DHFR
| 5件: One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance 5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬1. DHFR
| Methotrexate | 38件: 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 1. DHFR
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| 2 |
DHODH
💬2. DHODH
| 3件: Pyrimidine metabolism Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors | Leflunomide
Leflunomide
💬2. DHODH
| Leflunomide | 12件: 11 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬2. DHODH
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| 3 |
DHODH
💬3. DHODH
| 3件: Pyrimidine metabolism Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors | Teriflunomide
Teriflunomide
💬3. DHODH
| Teriflunomide | 3件: 13 13, 25, 26 💬
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| 4 |
NQO1
💬4. NQO1
| 7件: Ubiquinone and other terpenoid-quinone biosynthesis Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis 7件: Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofacto ... | Warfarin
Warfarin
💬4. NQO1
| Warfarin | 11件: 6 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬4. NQO1
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| 5 |
DHFR2
💬5. DHFR2
| 5件: One carbon pool by folate One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance 5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ... | Methotrexate
Methotrexate
💬5. DHFR2
| Methotrexate | 38件: 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ... 5. DHFR2
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| 6 |
ALAS1
💬6. ALAS1
| 4件: Glycine, serine and threonine metabolism Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis of cofactors 4件: Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis ... | Hemin
Hemin
💬6. ALAS1
| Hemin | 1件: 254 254 💬6. ALAS1
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| 7 |
ALAS1
💬7. ALAS1
| 4件: Glycine, serine and threonine metabolism Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis of cofactors 4件: Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis ... | Givosiran
Givosiran
💬7. ALAS1
| Givosiran | 1件: 254 254 💬7. ALAS1
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| 8 |
ALAS2
💬8. ALAS2
| 4件: Glycine, serine and threonine metabolism Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis of cofactors 4件: Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis ... | Hemin
Hemin
💬8. ALAS2
| Hemin | 1件: 254 254 💬8. ALAS2
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| 9 |
ALPL
💬9. ALPL
| 4件: Thiamine metabolism Thiamine metabolism, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors | Asfotase alfa
Asfotase alfa
💬9. ALPL
| Asfotase alfa | 1件: 172 172 💬9. ALPL
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| 10 |
GUSB
💬10. GUSB
| 8件: Pentose and glucuronate interconversions Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Porphyrin metabolism, Drug metabolism - other enzymes, Metabolic pathways, Biosynthesis of cofactors, Lysosome 8件: Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Glycosaminoglycan d ... | Vestronidase alfa
Vestronidase alfa
💬10. GUSB
| Vestronidase alfa | 1件: 19 19 💬10. GUSB
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