Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adherens junction 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
2 Adrenergic signaling in cardiomyocytes 💬
 5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
3 Alcoholism 💬
 1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
4 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
5 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
6 Aldosterone synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
7 Aldosterone-regulated sodium reabsorption 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
8 Alzheimer disease 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
9 Alzheimer disease 💬
 3件: CHRM1, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
10 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
11 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
12 Alzheimer disease 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
13 Amphetamine addiction 💬
 6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
14 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
15 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
16 AMPK signaling pathway 💬
 1件: HMGCR 💬 Lovastatin 💬 Lovastatin 11件:  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
17 AMPK signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
18 Amyotrophic lateral sclerosis 💬
 2件: GRIA1, GRIA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
19 Amyotrophic lateral sclerosis 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
20 Amyotrophic lateral sclerosis 💬
 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
21 Amyotrophic lateral sclerosis 💬
 1件: SIGMAR1 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
22 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
23 Bile secretion 💬
 1件: CA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
24 Bile secretion 💬
 1件: HMGCR 💬 Lovastatin 💬 Lovastatin 11件:  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
25 Calcium signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
26 Calcium signaling pathway 💬
 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
27 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
28 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
29 Calcium signaling pathway 💬
 1件: HTR2A 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
30 cAMP signaling pathway 💬
 8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
31 cAMP signaling pathway 💬
 2件: CHRM1, CHRM2 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
32 cAMP signaling pathway 💬
 1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
33 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
34 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
35 Carbohydrate digestion and absorption 💬
 1件: CACNA1D 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
36 Cardiac muscle contraction 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
37 Cellular senescence 💬
 1件: CACNA1D 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
38 cGMP-PKG signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
39 cGMP-PKG signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
40 Chemical carcinogenesis - receptor activation 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
41 Cholinergic synapse 💬
 1件: ACHE 💬 Donepezil 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
42 Cholinergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
43 Cholinergic synapse 💬
 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
44 Circadian entrainment 💬
 6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
45 Circadian entrainment 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
46 Circadian entrainment 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
47 Cocaine addiction 💬
 1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
48 Cocaine addiction 💬
 1件: GRIA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
49 Cocaine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
50 Cocaine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
51 Collecting duct acid secretion 💬
 1件: CA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
52 Cortisol synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
53 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
54 Diabetic cardiomyopathy 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
55 Dilated cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
56 Dopaminergic synapse 💬
 7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
57 Dopaminergic synapse 💬
 1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
58 Dopaminergic synapse 💬
 2件: GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
59 Dopaminergic synapse 💬
 2件: GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
60 FoxO signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
61 FoxO signaling pathway 💬
 1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬 💬
62 GABAergic synapse 💬
 20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
63 Gap junction 💬
 2件: DRD2, HTR2A 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
64 Gastric acid secretion 💬
 1件: CA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
65 Gastric acid secretion 💬
 1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
66 Glutamatergic synapse 💬
 11件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
67 Glutamatergic synapse 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
68 Glutamatergic synapse 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
69 Glycerophospholipid metabolism 💬
 1件: ACHE 💬 Donepezil 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
70 GnRH secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
71 GnRH signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
72 Growth hormone synthesis, secretion and action 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
73 HIF-1 signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
74 Huntington disease 💬
 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
75 Huntington disease 💬
 2件: GRIN1, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
76 Huntington disease 💬
 2件: GRIN1, GRIN2B 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
77 Hypertrophic cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
78 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2A 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
79 Insulin resistance 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
80 Insulin secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
81 Insulin secretion 💬
 1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
82 Insulin signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
83 Long-term depression 💬
 3件: GRIA1, GRIA2, GRIA3 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
84 Long-term potentiation 💬
 3件: CACNA1C, GRIA1, GRIA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
85 Long-term potentiation 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
86 Long-term potentiation 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
87 Longevity regulating pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
88 Longevity regulating pathway - multiple species 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
89 MAPK signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
90 MAPK signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
91 Metabolic pathways 💬
 2件: CA2, CA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
92 Metabolic pathways 💬
 1件: HMGCR 💬 Lovastatin 💬 Lovastatin 11件:  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
93 Morphine addiction 💬
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
94 mTOR signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
95 Neuroactive ligand-receptor interaction 💬
 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
96 Neuroactive ligand-receptor interaction 💬
 2件: CNR1, CNR2 💬 Cannabidiol 💬 Cannabidiol 20件:  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
97 Neuroactive ligand-receptor interaction 💬
 2件: DRD2, HTR2A 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
98 Neuroactive ligand-receptor interaction 💬
 25件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
99 Neuroactive ligand-receptor interaction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
100 Neuroactive ligand-receptor interaction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
101 Neuroactive ligand-receptor interaction 💬
 1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬 💬
102 Nicotine addiction 💬
 20件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
103 Nicotine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
104 Nicotine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
105 Nitrogen metabolism 💬
 2件: CA2, CA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
106 Non-alcoholic fatty liver disease 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
107 Ovarian steroidogenesis 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
108 Oxytocin signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
109 Pancreatic secretion 💬
 1件: CA2 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
110 Pancreatic secretion 💬
 1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
111 Parkinson disease 💬
 1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
112 Pathways of neurodegeneration - multiple diseases 💬
 8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
113 Pathways of neurodegeneration - multiple diseases 💬
 4件: CHRM1, CHRM3, CHRM5, SIGMAR1 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
114 Pathways of neurodegeneration - multiple diseases 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
115 Pathways of neurodegeneration - multiple diseases 💬
 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
116 Phospholipase D signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
117 PI3K-Akt signaling pathway 💬
 2件: CHRM1, CHRM2 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
118 PI3K-Akt signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
119 Prion disease 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
120 Prion disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
121 Prion disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
122 Proximal tubule bicarbonate reclamation 💬
 2件: CA2, CA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
123 Rap1 signaling pathway 💬
 1件: CNR1 💬 Cannabidiol 💬 Cannabidiol 20件:  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
124 Rap1 signaling pathway 💬
 1件: DRD2 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
125 Rap1 signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
126 Rap1 signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
127 Rap1 signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
128 Ras signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
129 Ras signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
130 Ras signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
131 Regulation of actin cytoskeleton 💬
 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
132 Regulation of lipolysis in adipocytes 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
133 Renin secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
134 Retrograde endocannabinoid signaling 💬
 24件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
135 Retrograde endocannabinoid signaling 💬
 1件: CNR1 💬 Cannabidiol 💬 Cannabidiol 20件:  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
136 Salivary secretion 💬
 1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
137 Serotonergic synapse 💬
 7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
138 Serotonergic synapse 💬
 1件: HTR2A 💬 Risperidone 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬 💬
139 Serotonergic synapse 💬
 1件: SLC6A4 💬 Desipramine 💬 Desipramine 2件: 120, 156 💬 💬
140 Sphingolipid signaling pathway 💬
 1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬 💬
141 Spinocerebellar ataxia 💬
 3件: GRIA1, GRIA2, GRIA3 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
142 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
143 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
144 Synaptic vesicle cycle 💬
 2件: SLC6A2, SLC6A4 💬 Desipramine 💬 Desipramine 2件: 120, 156 💬 💬
145 Systemic lupus erythematosus 💬
 2件: GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
146 Systemic lupus erythematosus 💬
 2件: GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
147 Taste transduction 💬
 10件: CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
148 Taste transduction 💬
 1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
149 Terpenoid backbone biosynthesis 💬
 1件: HMGCR 💬 Lovastatin 💬 Lovastatin 11件:  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬
150 Thermogenesis 💬
 1件: CNR1 💬 Cannabidiol 💬 Cannabidiol 20件:  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 💬
151 Tight junction 💬
 1件: CACNA1D 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
152 Transcriptional misregulation in cancer 💬
 1件: GRIA3 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
153 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
154 Type II diabetes mellitus 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 2件: 96, 156 💬 💬
155 Vascular smooth muscle contraction 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬

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