Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Neutrophil extracellular trap formation 💬
 1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬 💬
2 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Crovalimab 💬 Crovalimab 2件: 62, 109 💬 💬
3 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Eculizumab 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬 💬
4 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Nomacopan 💬 Nomacopan 3件: 62, 109, 162 💬 💬
5 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Pozelimab 💬 Pozelimab 2件: 11, 62 💬 💬
6 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬 💬
7 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬 💬
8 Neutrophil extracellular trap formation 💬
 1件: C5 💬 Zilucoplan 💬 Zilucoplan 3件:  2 , 11, 62 💬 💬
9 Neutrophil extracellular trap formation 💬
 1件: C5AR1 💬 Avacopan 💬 Avacopan 3件: 43, 44, 222 💬 💬
10 Neutrophil extracellular trap formation 💬
 1件: ELANE 💬 Sivelestat 💬 Sivelestat 3件: 13, 85, 96 💬 💬
11 Neutrophil extracellular trap formation 💬
 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬 💬
12 Neutrophil extracellular trap formation 💬
 1件: ITGAL 💬 Efalizumab 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬
13 Neutrophil extracellular trap formation 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬 💬
14 Neutrophil extracellular trap formation 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬 💬
15 Neutrophil extracellular trap formation 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬 💬
16 Neutrophil extracellular trap formation 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬 💬
17 Neutrophil extracellular trap formation 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬 💬
18 Neutrophil extracellular trap formation 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
19 Neutrophil extracellular trap formation 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
20 Neutrophil extracellular trap formation 💬
 1件: MPO 💬 Verdiperstat 💬 Verdiperstat 3件:  2 , 17, 127 💬 💬
21 Neutrophil extracellular trap formation 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
22 Neutrophil extracellular trap formation 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
23 Neutrophil extracellular trap formation 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
24 Neutrophil extracellular trap formation 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
25 Neutrophil extracellular trap formation 💬
 1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
26 Neutrophil extracellular trap formation 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
27 Neutrophil extracellular trap formation 💬
 1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
28 Neutrophil extracellular trap formation 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
29 Neutrophil extracellular trap formation 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
30 Neutrophil extracellular trap formation 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
31 Neutrophil extracellular trap formation 💬
 1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬 💬
32 Neutrophil extracellular trap formation 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
33 Neutrophil extracellular trap formation 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
34 Neutrophil extracellular trap formation 💬
 1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬 💬
35 Neutrophil extracellular trap formation 💬
 1件: SYK 💬 Fostamatinib 💬 Fostamatinib 4件: 46, 49, 61, 66 💬 💬
36 Neutrophil extracellular trap formation 💬
 1件: TLR7 💬 Imiquimod 💬 Imiquimod 2件: 34, 51 💬 💬
37 Neutrophil extracellular trap formation 💬
 1件: VWF 💬 Caplacizumab 💬 Caplacizumab 1件: 64 💬 💬