Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Amlodipine Amlodipine 💬
| Amlodipine | 013 4件: 13, 51, 67, 298 💬
|
| 2 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Cilnidipine Cilnidipine 💬
| Cilnidipine | 067 1件: 67 💬
|
| 3 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Diltiazem Diltiazem 💬
| Diltiazem | 051 3件: 51, 58, 86 💬
|
| 4 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Isradipine Isradipine 💬
| Isradipine | 006 1件: 6 💬
|
| 5 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Nicardipine Nicardipine 💬
| Nicardipine | 070 2件: 70, 86 💬
|
| 6 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 7 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Nilvadipine Nilvadipine 💬
| Nilvadipine | 090 1件: 90 💬
|
| 8 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Perhexiline Perhexiline 💬
| Perhexiline | 058 2件: 58, 272 💬
|
| 9 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Propiverine Propiverine 💬
| Propiverine | 226 1件: 226 💬
|
| 10 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬
|
| 11 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Verapamil Verapamil 💬
| Verapamil | 058 4件: 58, 96, 140, 167 💬
|
| 12 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CDK4 2件: CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 1件: 34 💬
|
| 13 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 14 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 1件: IL1A 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 15 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 16 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 1件: IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 2件: 46, 96 💬
|
| 17 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 1件: IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬
|
| 18 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 1件: IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 2件: 28, 331 💬
|
| 19 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
| 20 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
| 21 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 22 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 1件: 34 💬
|
| 23 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
| 24 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 25 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 2件: 113, 222 💬
|
| 26 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 1件: 8 💬
|
| 27 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
| 28 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 29 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 1件: 13 💬
|
| 30 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
NFKB1 1件: NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬
|
| 31 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PIK3CA 1件: PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 1件: 138 💬
|
| 32 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
| 33 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PIK3CD 1件: PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
| 34 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 35 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Pimecrolimus Pimecrolimus 💬
| Pimecrolimus | 160 1件: 160 💬
|
| 36 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 37 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 38 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Voclosporin Voclosporin 💬
| Voclosporin | 049 2件: 49, 222 💬
|
| 39 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 40 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
RELA 1件: RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 1件: 113 💬
|
| 41 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 3件: 51, 85, 222 💬
|