Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 2 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CSF2 1件: CSF2 💬
|
Otilimab Otilimab 💬
| Otilimab | 046 1件: 46 💬
|
| 3 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
| 4 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 5 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 6 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 1件: IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 2件: 46, 96 💬
|
| 7 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 1件: IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 2件: 28, 331 💬
|
| 8 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
| 9 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 2件: IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬
|
| 10 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
LTA 1件: LTA 💬
|
Pateclizumab Pateclizumab 💬
| Pateclizumab | 046 1件: 46 💬
|
| 11 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 12 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
| 13 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 14 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 1件: 34 💬
|
| 15 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
| 16 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 17 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP3K5 1件: MAP3K5 💬
|
Selonsertib Selonsertib 💬
| Selonsertib | 086 1件: 86 💬
|
| 18 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 2件: 113, 222 💬
|
| 19 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 1件: 8 💬
|
| 20 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
NFKB1 1件: NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬
|
| 21 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PIK3CA 1件: PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 1件: 138 💬
|
| 22 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
| 23 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PIK3CD 1件: PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
| 24 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Aceclofenac Aceclofenac 💬
| Aceclofenac | 046 1件: 46 💬
|
| 25 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Acetaminophen Acetaminophen 💬
| Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
|
| 26 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Aspirin Aspirin 💬
| Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
|
| 27 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Celecoxib Celecoxib 💬
| Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
|
| 28 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Diclofenac Diclofenac 💬
| Diclofenac | 013 5件: 13, 34, 46, 78, 271 💬
|
| 29 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Diflunisal Diflunisal 💬
| Diflunisal | 028 1件: 28 💬
|
| 30 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Etodolac Etodolac 💬
| Etodolac | 046 1件: 46 💬
|
| 31 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Etoricoxib Etoricoxib 💬
| Etoricoxib | 046 2件: 46, 271 💬
|
| 32 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Flurbiprofen Flurbiprofen 💬
| Flurbiprofen | 013 3件: 13, 21, 46 💬
|
| 33 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Ibuprofen Ibuprofen 💬
| Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬
|
| 34 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Indomethacin Indomethacin 💬
| Indomethacin | 225 3件: 225, 271, 298 💬
|
| 35 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Ketoprofen Ketoprofen 💬
| Ketoprofen | 046 1件: 46 💬
|
| 36 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Ketorolac Ketorolac 💬
| Ketorolac | 070 2件: 70, 226 💬
|
| 37 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Loxoprofen Loxoprofen 💬
| Loxoprofen | 046 2件: 46, 271 💬
|
| 38 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Lumiracoxib Lumiracoxib 💬
| Lumiracoxib | 046 1件: 46 💬
|
| 39 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Meloxicam Meloxicam 💬
| Meloxicam | 046 4件: 46, 49, 271, 296 💬
|
| 40 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Naproxen Naproxen 💬
| Naproxen | 013 4件: 13, 46, 107, 271 💬
|
| 41 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Nimesulide Nimesulide 💬
| Nimesulide | 046 1件: 46 💬
|
| 42 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Parecoxib Parecoxib 💬
| Parecoxib | 046 2件: 46, 271 💬
|
| 43 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Rofecoxib Rofecoxib 💬
| Rofecoxib | 046 1件: 46 💬
|
| 44 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Salsalate Salsalate 💬
| Salsalate | 005 1件: 5 💬
|
| 45 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Sulindac Sulindac 💬
| Sulindac | 206 1件: 206 💬
|
| 46 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Tolfenamic acid Tolfenamic acid 💬
| Tolfenamic acid | 005 1件: 5 💬
|
| 47 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 1件: PTGS2 💬
|
Valdecoxib Valdecoxib 💬
| Valdecoxib | 046 1件: 46 💬
|
| 48 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
RELA 1件: RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 1件: 113 💬
|
| 49 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
| 50 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
|
| 51 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 52 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 53 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 54 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 1件: 46 💬
|
| 55 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 1件: 46 💬
|
| 56 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|