Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 2 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 3 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Crovalimab Crovalimab 💬
| Crovalimab | 062 2件: 62, 109 💬
|
| 4 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Eculizumab Eculizumab 💬
| Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬
|
| 5 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Nomacopan Nomacopan 💬
| Nomacopan | 062 3件: 62, 109, 162 💬
|
| 6 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Pozelimab Pozelimab 💬
| Pozelimab | 011 2件: 11, 62 💬
|
| 7 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 8 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Vilobelimab Vilobelimab 💬
| Vilobelimab | 043 3件: 43, 44, 269 💬
|
| 9 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Zilucoplan Zilucoplan 💬
| Zilucoplan | 002 3件: 2 , 11, 62 💬
|
| 10 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Atropine Atropine 💬
| Atropine | 002 2件: 2 , 299 💬
|
| 11 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Blarcamesine Blarcamesine 💬
| Blarcamesine | 156 1件: 156 💬
|
| 12 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Chlorpromazine Chlorpromazine 💬
| Chlorpromazine | 254 1件: 254 💬
|
| 13 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Oxybutynin Oxybutynin 💬
| Oxybutynin | 006 3件: 6 , 13, 53 💬
|
| 14 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Propiverine Propiverine 💬
| Propiverine | 226 1件: 226 💬
|
| 15 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Scopolamine Scopolamine 💬
| Scopolamine | 002 1件: 2 💬
|
| 16 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Trihexyphenidyl Trihexyphenidyl 💬
| Trihexyphenidyl | 005 2件: 5 , 6 💬
|
| 17 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Tropicamide Tropicamide 💬
| Tropicamide | 006 1件: 6 💬
|
| 18 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM2 2件: CHRM2, CHRM3 💬
|
Fesoterodine Fesoterodine 💬
| Fesoterodine | 006 1件: 6 💬
|
| 19 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM2 2件: CHRM2, CHRM3 💬
|
Pilocarpine Pilocarpine 💬
| Pilocarpine | 006 3件: 6 , 53, 299 💬
|
| 20 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 1件: CHRM3 💬
|
Cevimeline Cevimeline 💬
| Cevimeline | 053 1件: 53 💬
|
| 21 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 1件: CHRM3 💬
|
Darifenacin Darifenacin 💬
| Darifenacin | 006 2件: 6 , 13 💬
|
| 22 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 1件: CHRM3 💬
|
Solifenacin Solifenacin 💬
| Solifenacin | 006 3件: 6 , 13, 53 💬
|
| 23 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CHRM3 1件: CHRM3 💬
|
Tolterodine Tolterodine 💬
| Tolterodine | 017 2件: 17, 53 💬
|
| 24 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
CXCR4 1件: CXCR4 💬
|
Plerixafor Plerixafor 💬
| Plerixafor | 019 5件: 19, 20, 65, 285, 299 💬
|
| 25 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 2件: 51, 86 💬
|
| 26 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 1件: 94 💬
|
| 27 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 1件: 75 💬
|
| 28 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 1件: 34 💬
|
| 29 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 3件: 34, 74, 75 💬
|
| 30 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 1件: 34 💬
|
| 31 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
EGFR 1件: EGFR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 32 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 1件: F2 💬
|
Dabigatran Dabigatran 💬
| Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬
|
| 33 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 1件: F2 💬
|
Dabigatran etexilate Dabigatran etexilate 💬
| Dabigatran etexilate | 051 2件: 51, 75 💬
|
| 34 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
F2 1件: F2 💬
|
Thrombomodulin alfa Thrombomodulin alfa 💬
| Thrombomodulin Alfa | 085 1件: 85 💬
|
| 35 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGF23 1件: FGF23 💬
|
Burosumab Burosumab 💬
| Burosumab | 238 1件: 238 💬
|
| 36 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬
|
Infigratinib Infigratinib 💬
| Infigratinib | 276 1件: 276 💬
|
| 37 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR1 5件: FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 38 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
FGFR2 1件: FGFR2 💬
|
Palifermin Palifermin 💬
| Palifermin | 013 5件: 13, 36, 38, 39, 65 💬
|
| 39 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 1件: ITGA4 💬
|
Firategrast Firategrast 💬
| Firategrast | 013 1件: 13 💬
|
| 40 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 1件: ITGA4 💬
|
Natalizumab Natalizumab 💬
| Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬
|
| 41 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 2件: ITGA4, ITGB7 💬
|
Abrilumab Abrilumab 💬
| Abrilumab | 096 2件: 96, 97 💬
|
| 42 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 2件: ITGA4, ITGB7 💬
|
Vedolizumab Vedolizumab 💬
| Vedolizumab | 094 3件: 94, 96, 97 💬
|
| 43 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGAL 1件: ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
|
| 44 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGB7 1件: ITGB7 💬
|
Etrolizumab Etrolizumab 💬
| Etrolizumab | 096 2件: 96, 97 💬
|
| 45 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
| 46 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 47 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 1件: 34 💬
|
| 48 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
| 49 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 50 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA 1件: PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 51 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA 2件: PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬
|
| 52 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRA 2件: PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 53 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB 2件: PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 54 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PDGFRB 2件: PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 55 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PIK3CA 1件: PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 1件: 138 💬
|
| 56 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
| 57 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
PIK3CD 1件: PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
| 58 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK1 2件: ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 4件: 2 , 5 , 7 , 51 💬
|
| 59 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ROCK2 1件: ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 2件: 51, 85 💬
|
| 60 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
SRC 1件: SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 2件: 2 , 67 💬
|
| 61 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
SRC 1件: SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 3件: 6 , 89, 272 💬
|