Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
3 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬
4 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
5 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
6 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 2件: 50, 81 💬
7 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
8 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
9 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
10 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
11 Oxytocin signaling pathway 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
12 Oxytocin signaling pathway 💬
2件: CACNA2D1, CACNA2D2 💬 Mirogabalin 💬 Mirogabalin 1件: 70 💬
13 Oxytocin signaling pathway 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
14 Oxytocin signaling pathway 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬
15 Oxytocin signaling pathway 💬
1件: CD38 💬 Daratumumab 💬 Daratumumab 5件: 13, 28, 48, 49, 63 💬
16 Oxytocin signaling pathway 💬
1件: CD38 💬 Isatuximab 💬 Isatuximab 3件: 28, 61, 283 💬
17 Oxytocin signaling pathway 💬
1件: CD38 💬 Mezagitamab 💬 Mezagitamab 2件: 63, 66 💬
18 Oxytocin signaling pathway 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬
19 Oxytocin signaling pathway 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 1件: 94 💬
20 Oxytocin signaling pathway 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
21 Oxytocin signaling pathway 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
22 Oxytocin signaling pathway 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
23 Oxytocin signaling pathway 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
24 Oxytocin signaling pathway 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
25 Oxytocin signaling pathway 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite 1件: 58 💬
26 Oxytocin signaling pathway 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
27 Oxytocin signaling pathway 💬
3件: KCNJ12, KCNJ3, KCNJ5 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬
28 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
29 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
30 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
31 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
32 Oxytocin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
33 Oxytocin signaling pathway 💬
1件: NPR1 💬 Nesiritide 💬 Nesiritide 2件: 46, 58 💬
34 Oxytocin signaling pathway 💬
2件: NPR1, NPR2 💬 Erythrityl tetranitrate 💬 Erythrityl tetranitrate 1件: 46 💬
35 Oxytocin signaling pathway 💬
1件: NPR2 💬 Vosoritide 💬 Vosoritide 1件: 276 💬
36 Oxytocin signaling pathway 💬
1件: OXTR 💬 Atosiban 💬 Atosiban 1件: 118 💬
37 Oxytocin signaling pathway 💬
1件: OXTR 💬 Oxytocin 💬 Oxytocin 7件:  6 , 72, 127, 168, 193, 206, 226 💬
38 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
39 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬
40 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
41 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
42 Oxytocin signaling pathway 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬
43 Oxytocin signaling pathway 💬
2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
44 Oxytocin signaling pathway 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
45 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
46 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
47 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
48 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Celecoxib 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
49 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
50 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
51 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Etodolac 💬 Etodolac 1件: 46 💬
52 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 2件: 46, 271 💬
53 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
54 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
55 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
56 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 1件: 46 💬
57 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
58 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
59 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
60 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Meloxicam 💬 Meloxicam 4件: 46, 49, 271, 296 💬
61 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
62 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
63 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
64 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
65 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
66 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
67 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
68 Oxytocin signaling pathway 💬
1件: PTGS2 💬 Valdecoxib 💬 Valdecoxib 1件: 46 💬
69 Oxytocin signaling pathway 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
70 Oxytocin signaling pathway 💬
2件: ROCK1, ROCK2 💬 Fasudil 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
71 Oxytocin signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 2件: 51, 85 💬
72 Oxytocin signaling pathway 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
73 Oxytocin signaling pathway 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
74 Oxytocin signaling pathway 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
75 Oxytocin signaling pathway 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬