Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
2 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
3 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬 💬
4 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
5 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
6 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬 💬
7 Chemical carcinogenesis - reactive oxygen species 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬 💬
8 Chemical carcinogenesis - reactive oxygen species 💬
2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
9 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
10 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 1件: 94 💬 💬
11 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬 💬
12 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬 💬
13 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬 💬
14 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬 💬
15 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬 💬
16 Chemical carcinogenesis - reactive oxygen species 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬 💬
17 Chemical carcinogenesis - reactive oxygen species 💬
1件: KEAP1 💬 Dimethyl fumarate 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬 💬
18 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬 💬
19 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬 💬
20 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬 💬
21 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬 💬
22 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬 💬
23 Chemical carcinogenesis - reactive oxygen species 💬
1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
24 Chemical carcinogenesis - reactive oxygen species 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
25 Chemical carcinogenesis - reactive oxygen species 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
26 Chemical carcinogenesis - reactive oxygen species 💬
1件: MET 💬 Cabozantinib 💬 Cabozantinib 1件: 34 💬 💬
27 Chemical carcinogenesis - reactive oxygen species 💬
1件: NFE2L2 💬 Omaveloxolone 💬 Omaveloxolone 1件: 18 💬 💬
28 Chemical carcinogenesis - reactive oxygen species 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
29 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
30 Chemical carcinogenesis - reactive oxygen species 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
31 Chemical carcinogenesis - reactive oxygen species 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
32 Chemical carcinogenesis - reactive oxygen species 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
33 Chemical carcinogenesis - reactive oxygen species 💬
1件: PRKCD 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬 💬
34 Chemical carcinogenesis - reactive oxygen species 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
35 Chemical carcinogenesis - reactive oxygen species 💬
1件: SOD1 💬 Tofersen 💬 Tofersen 1件:  2  💬 💬
36 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬 💬
37 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬 💬
38 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬 💬