Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
12% sodium chondroitin sulfate[2] Chondroitin sulfate,
Sulfate ion		---[1] 226 💬
25% lidocaine/5 mg/ml 0.02% estradiol compound cream[2] Estradiol,
Lidocaine		[3] Estradiol ,
Lidocaine ,
Lidocaine hydrochloride monohydrate 💬 		[7] ESR1,
ESR2,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[13] Adrenergic signaling in cardiomyocytes, Breast cancer, Chemical carcinogenesis - receptor activation, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Taste transduction, Thyroid hormone signaling pathway 💬[1] 226 💬
3Adalimumab[1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
4AGN 203818----[1] 226 💬
5Alkalinized Lidocaine-Heparin[2] Heparin,
Lidocaine		[3] Lidocaine ,
Adomiparin ,
Lidocaine hydrochloride monohydrate 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SERPINC1 💬 		[4] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Taste transduction 💬[1] 226 💬
6AlloRx----[8] 2, 6, 13, 46, 51, 85, 90, 226 💬
7Aloe[1] Aloe vera leaf---[2] 97, 226 💬
8Aloe vera[1] Aloe vera leaf---[2] 97, 226 💬
9Amitriptyline[1] Amitriptyline[1] Amitriptyline 💬 [2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299 💬
10AQX-1125[1] AQX-1125---[1] 226 💬
11AQX-1125 100 mg[1] AQX-1125---[1] 226 💬
12AQX-1125 200 mg[1] AQX-1125---[1] 226 💬
13ASP3652----[1] 226 💬
14ASP6294----[1] 226 💬
15Bladder instillation with heparin/ lidocaine[2] Heparin,
Lidocaine		[3] Lidocaine ,
Adomiparin ,
Lidocaine hydrochloride monohydrate 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SERPINC1 💬 		[4] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Taste transduction 💬[1] 226 💬
16Bladder instillation WITH triamcinolone acetonide[1] Triamcinolone[1] Triamcinolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 226 💬
17Bladder instillation WITHOUT triamcinolone acetonide[1] Triamcinolone[1] Triamcinolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 226 💬
18Bladder Instillations----[1] 226 💬
19Bladder tissue of Interstitial Cystitis and normal bladder tissue----[1] 226 💬
20Botox[1] Botulinum toxin type A[1] Botulinum toxin type A 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[7] 2, 6, 13, 47, 51, 149, 226 💬
21BOTOX 100U in normal saline[1] Botulinum toxin type A[1] Botulinum toxin type A 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[1] 226 💬
22BOTOX 200U in normal saline[1] Botulinum toxin type A[1] Botulinum toxin type A 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[1] 226 💬
23Botulinum Neurotoxin----[1] 226 💬
24Botulinum toxin A[1] Botulinum toxin type A[1] Botulinum toxin type A 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[4] 13, 51, 149, 226 💬
25Buckwheat[1] Buckwheat---[1] 226 💬
26Bupivacaine[1] Bupivacaine[1] Bupivacaine 💬 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
27Bupivacaine, triamcinolone, and heparin (BTH)[3] Bupivacaine,
Heparin,
Triamcinolone		[3] Triamcinolone ,
Adomiparin ,
Bupivacaine 💬 		[7] NR3C1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SERPINC1 💬 		[5] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Neuroactive ligand-receptor interaction, Taste transduction 💬[1] 226 💬
28Cannabidiol[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
29Cannabidiol vaginal suppository[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 226 💬
30Capsaicin[1] Capsaicin[1] Capsaicin 💬 [1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226 💬
31Certolizumab Pegol[1] Certolizumab pegol[1] Certolizumab pegol 💬 [1] TNF 💬 [67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
32Chondroitin sulfate[2] Chondroitin sulfate,
Sulfate ion		---[2] 96, 226 💬
33Ciclosporin[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[13] 26, 46, 49, 50, 53, 55, 60, 61, 97, 222, 226, 228, 269 💬
34Ciklosporin----[1] 226 💬
35Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬
36Desert Harvest Aloe Vera Capsules[1] Aloe vera leaf---[1] 226 💬
37DEXMEDETOMIDINE[1] Dexmedetomidine[1] Dexmedetomidine 💬 [3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
38Dextrose[1] Dextrose, unspecified form---[4] 60, 65, 70, 226 💬
39Dimethyl sulfoxide[1] Dimethyl sulfoxide[1] Dimethyl sulfoxide 💬 --[1] 226 💬
40Dimethyl sulfoxide (DMSO)[1] Dimethyl sulfoxide[1] Dimethyl sulfoxide 💬 --[1] 226 💬
41DMSO[1] Dimethyl sulfoxide[1] Dimethyl sulfoxide 💬 --[1] 226 💬
42DMSO cocktail[1] Dimethyl sulfoxide[1] Dimethyl sulfoxide 💬 --[1] 226 💬
43ERB-041----[3] 46, 96, 226 💬
44Estradiol[1] Estradiol[1] Estradiol 💬 [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299 💬
45Flavoxate[1] Flavoxate[1] Flavoxate 💬 [16] PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		[18] Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
46Fospropofol[1] Fospropofol---[1] 226 💬
47Fospropofol (Lusedra®) 10[1] Fospropofol---[1] 226 💬
48Fospropofol (Lusedra®) 12[1] Fospropofol---[1] 226 💬
49Fospropofol (Lusedra®) 6.5[1] Fospropofol---[1] 226 💬
50Fremanezumab[1] Fremanezumab[1] Fremanezumab 💬 [1] CALCA 💬 [2] Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction 💬[2] 124, 226 💬
51Gefapixant[1] Gefapixant[1] Gefapixant 💬 [1] P2RX3 💬 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction 💬[2] 85, 226 💬
52GLYCINE[1] Glycine[1] Glycine 💬 --[5] 35, 60, 86, 226, 299 💬
53Gold[1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
54Gralise----[2] 97, 226 💬
55Heparin[1] Heparin[1] Adomiparin 💬 [1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬
56Heparin & Alkalinized Lidocaine Bladder Instillation[2] Heparin,
Lidocaine		[3] Lidocaine ,
Adomiparin ,
Lidocaine hydrochloride monohydrate 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SERPINC1 💬 		[4] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Taste transduction 💬[1] 226 💬
57Hyaluronic acid[1] Hyaluronic acid[1] Hyaluronic acid 💬 --[5] 46, 53, 70, 226, 231 💬
58Hyaluronic Acid and Chondroitin Sulfate[3] Chondroitin sulfate,
Hyaluronic acid,
Sulfate ion		[1] Hyaluronic acid 💬 --[1] 226 💬
59Hyaluronic acid/chondroitin sulfate[3] Chondroitin sulfate,
Hyaluronic acid,
Sulfate ion		[1] Hyaluronic acid 💬 --[1] 226 💬
60Hydrogen[1] Hydrogen---[6] 5, 6, 17, 83, 97, 226 💬
61IC Cocktail----[1] 226 💬
62Immunonutrition----[2] 96, 226 💬
63Intravesical onabotulinumtoxinA injection[1] Botulinum toxin type A[1] Botulinum toxin type A 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[1] 226 💬
64IPD® (Japanese tradename)----[1] 226 💬
65IPD® (suplatast tosilate)----[1] 226 💬
66IW-3300 rectal foam----[1] 226 💬
67JNJ-42160443----[1] 226 💬
68Ketorolac[1] Ketorolac[1] Ketorolac 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 70, 226 💬
69Ketorolac Tromethamine[2] Ketorolac,
Tromethamine		[2] Tromethamine ,
Ketorolac 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 226 💬
70KRP-116D----[1] 226 💬
71Lidocaine[1] Lidocaine[2] Lidocaine ,
Lidocaine hydrochloride monohydrate 💬 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[12] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 256 💬
72Lidocaine Releasing Intravesical System - LiRIS®[1] Lidocaine[2] Lidocaine ,
Lidocaine hydrochloride monohydrate 💬 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 226 💬
73Liposome encapsulated BoNT-A----[1] 226 💬
74Liposomes----[1] 226 💬
75LiRIS 400 mg----[1] 226 💬
76LiRIS low dose and LiRIS high dose----[1] 226 💬
77LiRIS®----[1] 226 💬
78LiRIS® 400 mg----[1] 226 💬
79Low-dose naltrexone[1] Naltrexone[1] Naltrexone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
80LP-08 20mg----[1] 226 💬
81LP-08 80mg----[1] 226 💬
82Metoprolol[1] Metoprolol[1] Metoprolol 💬 [1] ADRB1 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
83Metoprolol Tartrate Oral Tablet[1] Metoprolol[1] Metoprolol 💬 [1] ADRB1 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
84Mirabegron[1] Mirabegron[1] Mirabegron 💬 [1] ADRB3 💬 [8] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
85MMF----[16] 13, 35, 40, 46, 49, 50, 51, 60, 65, 66, 107, 162, 222, 224, 226, 299 💬
86MN-001----[1] 226 💬
87MN-001 BID----[1] 226 💬
88MR-MC-01----[1] 226 💬
89Multimodal Bundle Drugs----[1] 226 💬
90Mycofenolate Mofetil (MMF)----[1] 226 💬
91Mycophenolate[1] Mycophenolic acid[1] Mycophenolic acid 💬 [2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
92Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[2] Mycophenolate mofetil ,
Mycophenolic acid 💬 		[2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
93Naloxone[1] Naloxone[1] Naloxone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
94NALOXONE HYDROCHLORIDE[1] Naloxone[1] Naloxone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
95Naltrexone[1] Naltrexone[1] Naltrexone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
96Normal Saline----[18] 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299 💬
97Normal saline instillation----[1] 226 💬
98Nortriptyline[1] Nortriptyline[1] Nortriptyline 💬 [2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
99OMALIZUMAB[1] Omalizumab[1] Omalizumab 💬 [1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
100Onabotulinum Toxin A----[1] 226 💬
101Onabotulinumtoxin A----[2] 51, 226 💬
102OnabotulinumtoxinA[1] Botulinum toxin type A[1] Botulinum toxin type A 💬 [1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[4] 6, 13, 149, 226 💬
103OXN 10/5 mg PR----[1] 226 💬
104OXN 20/10 mg PR----[1] 226 💬
105OXN 5/2.5 mg PR----[1] 226 💬
106Oxycodone[1] Oxycodone[1] Oxycodone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
107OXYCODONE HYDROCHLORIDE[1] Oxycodone[1] Oxycodone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[4] 6, 70, 226, 298 💬
108Oxycodone naloxone prolonged release tablets[2] Naloxone,
Oxycodone		[2] Oxycodone ,
Naloxone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
109Oxycodone/naloxone prolonged release t[3] Manganese citrate,
Naloxone,
Oxycodone		[2] Oxycodone ,
Naloxone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
110Oxycodone/naloxone prolonged release tablets 10/5 mg[3] Manganese citrate,
Naloxone,
Oxycodone		[2] Oxycodone ,
Naloxone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
111Oxycodone/naloxone prolonged release tablets 20/10 mg[3] Manganese citrate,
Naloxone,
Oxycodone		[2] Oxycodone ,
Naloxone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
112Oxycodone/naloxone prolonged release tablets 5/2.5 mg[3] Manganese citrate,
Naloxone,
Oxycodone		[2] Oxycodone ,
Naloxone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
113Oxytocin[1] Oxytocin[1] Oxytocin 💬 [1] OXTR 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226 💬
114Ozone[1] Ozone---[3] 49, 51, 226 💬
115PD 0299685----[1] 226 💬
116PD 0299685 at 15mg BID----[1] 226 💬
117PD 0299685 at 30mg BID----[1] 226 💬
118PD-0299685[1] PD-0299685---[1] 226 💬
119Pentosan polysulfate[1] Pentosan polysulfate---[3] 19, 26, 226 💬
120Pentosan polysulfate sodium 100 mg[1] Pentosan polysulfate---[1] 226 💬
121PF-04383119----[1] 226 💬
122Placebo----[28] 3, 5, 6, 11, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬
123Platelet enriched plasma----[1] 226 💬
124Platelet-Rich Plasma----[1] 226 💬
125Prograf[1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[3] 60, 222, 226 💬
126Propiverine[1] Propiverine[1] Propiverine 💬 [9] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[43] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
127Propiverine Hydrochloride[1] Propiverine[1] Propiverine 💬 [9] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[43] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
128Release[1] Manganese citrate---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299 💬
129RIMSO 50----[1] 226 💬
130RN624, RI624----[1] 226 💬
131Sandimmun----[2] 97, 226 💬
132Sandimmun Neoral[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[3] 60, 97, 226 💬
133SI-722----[1] 226 💬
134Sildenafil[1] Sildenafil[1] Sildenafil 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
135Sulfate[1] Sulfate ion---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬
136Suplatast tosilate----[1] 226 💬
137Tacrolimus[1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
138Tanezumab[1] Tanezumab[1] Tanezumab 💬 [1] NGF 💬 [9] Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 226, 298 💬
139Targinact 10 mg/5 mg prolonged-release tablets[1] Manganese citrate---[2] 6, 226 💬
140Targinact 20mg/10 mg prolonged-release tablets[1] Manganese citrate---[1] 226 💬
141Targinact 5mg/2.5 mg prolonged-release tablets[1] Manganese citrate---[1] 226 💬
142Tramadol[1] Tramadol[1] Tramadol 💬 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271 💬
143Triamcinolone[1] Triamcinolone[1] Triamcinolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
144Tromethamine[1] Tromethamine[1] Tromethamine 💬 --[1] 226 💬
145TTI-1612----[1] 226 💬
146URG101----[1] 226 💬
147VNX001----[1] 226 💬
148Water[1] Water[1] Water 💬 --[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
149YM672----[1] 226 💬
150YM672 (IPD®)----[1] 226 💬