Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
43	Microscopic polyangiitis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
222	Primary nephrotic syndrome
296	Biliary atresia
300	IgG4-related disease

2

[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

[4] 13, 46, 49, 66 💬

3

[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

[2] 46, 49 💬

4

[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

Tibulizumab 💬

[1] 53 💬

5

[5] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

[7] 35, 46, 49, 53, 61, 63, 95 💬

6

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Losmapimod 💬

[2] 113, 222 💬

7

[62] Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...

Neflamapimod 💬

[1] 8 💬

8

[16] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...

[1] 46 💬

9

[44] Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa ...

Pirfenidone 💬

[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
58	Hypertrophic cardiomyopathy
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
164	Oculocutaneous albinism
222	Primary nephrotic syndrome
228	Bronchiolitis obliterans

10

[44] Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa ...

Rilonacept 💬

[4] 51, 106, 107, 266 💬

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