KEGG DRUG

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Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

50 mg Etanercept
(D00742)

[1] Etanercept

[1] Etanercept (D00742) 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 46 💬

Adalimuab, Etanercept, Tocilizumab, or Abatacept
(D00742)

[3] Abatacept,
Etanercept,
Tocilizumab

[3] Etanercept (D00742),
Tocilizumab ,
Abatacept 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)
Tocilizumab	Tocilizumab (USAN/INN) Tocilizumab (genetical recombination) (JAN) Actemra (TN)
Abatacept	Abatacept (USAN/INN) Abatacept (genetical recombination) (JAN) Orencia (TN)

[5] CD80,
CD86,
IL6R,
LTA,
TNF 💬

[80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 46 💬

Adalimumab, Etanercept, Golimumab or infliximab
(D00742)

[4] Adalimumab,
Etanercept,
Golimumab,
Infliximab

[4] Etanercept (D00742),
Adalimumab ,
Infliximab ,
Golimumab 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)
Adalimumab	Adalimumab (USAN/INN) Adalimumab (genetical recombination) (JAN) Adalimumab (genetical recombination) [Adalimumab biosimilar 1] (JAN) Adalimumab (genetical recombination) [Adalimumab biosimilar 2] (JAN) Adalimumab (genetical recombination) [Adalimumab biosimilar 3] (JAN) Adalimumab-adaz Adalimumab-adbm Adalimumab-afzb Adalimumab-atto Adalimumab-bwwd Adalimumab-fkjp Humira (TN) Abrilada (TN) Amjevita (TN) Cyltezo (TN) Hadlima (TN) Hyrimoz (TN)
Infliximab	Infliximab (USAN/INN) Infliximab (genetical recombination) (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 1] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 2] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 3] (JAN) Infliximab-dyyb Infliximab-abda Infliximab-axxq Remicade (TN) Inflectra (TN) Renflexis (TN) Avsola (TN)
Golimumab	Golimumab (USAN/INN) Golimumab (genetical recombination) (JAN) Simponi (TN) SIMPONI ARIA

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 271 💬

Anti-TNF therapy (etanercept or adalimumab)
(D00742)

[2] Adalimumab,
Etanercept

[2] Etanercept (D00742),
Adalimumab 💬

Name

Other Names

Etanercept

Etanercept (USAN/INN)
Etanercept (genetical recombination) (JAN)
Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN)
Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN)
Enbrel (TN)

Adalimumab

Adalimumab (USAN/INN)
Adalimumab (genetical recombination) (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 1] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 2] (JAN)
Adalimumab (genetical recombination) [Adalimumab biosimilar 3] (JAN)
Adalimumab-adaz
Adalimumab-adbm
Adalimumab-afzb
Adalimumab-atto
Adalimumab-bwwd
Adalimumab-fkjp
Humira (TN)
Abrilada (TN)
Amjevita (TN)
Cyltezo (TN)
Hadlima (TN)
Hyrimoz (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[2] 46, 271 💬

BDMARD withdrawal (etanercept, adalimumab, infliximab, certolizumab, golimumab, tozilizumab, abatace ...

[5] Abatacept,
Adalimumab,
Etanercept,
Golimumab,
Infliximab

[5] Etanercept (D00742),
Adalimumab ,
Infliximab ,
Abatacept ,
Golimumab 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)
Adalimumab	Adalimumab (USAN/INN) Adalimumab (genetical recombination) (JAN) Adalimumab (genetical recombination) [Adalimumab biosimilar 1] (JAN) Adalimumab (genetical recombination) [Adalimumab biosimilar 2] (JAN) Adalimumab (genetical recombination) [Adalimumab biosimilar 3] (JAN) Adalimumab-adaz Adalimumab-adbm Adalimumab-afzb Adalimumab-atto Adalimumab-bwwd Adalimumab-fkjp Humira (TN) Abrilada (TN) Amjevita (TN) Cyltezo (TN) Hadlima (TN) Hyrimoz (TN)
Infliximab	Infliximab (USAN/INN) Infliximab (genetical recombination) (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 1] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 2] (JAN) Infliximab (genetical recombination) [Infliximab biosimilar 3] (JAN) Infliximab-dyyb Infliximab-abda Infliximab-axxq Remicade (TN) Inflectra (TN) Renflexis (TN) Avsola (TN)
Abatacept	Abatacept (USAN/INN) Abatacept (genetical recombination) (JAN) Orencia (TN)
Golimumab	Golimumab (USAN/INN) Golimumab (genetical recombination) (JAN) Simponi (TN) SIMPONI ARIA

[4] CD80,
CD86,
LTA,
TNF 💬

[74] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 46 💬

Biosimilar Etanercept
(D00742)

[1] Etanercept

[1] Etanercept (D00742) 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 107 💬

Commercial Formulation Etanercept
(D00742)

[1] Etanercept

[1] Etanercept (D00742) 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 46 💬

Enbrel (Etanercept)
(D00742)

[1] Etanercept

[1] Etanercept (D00742) 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[4] 35, 46, 107, 271 💬

ETANERCEPT
(D00742)

[1] Etanercept

[1] Etanercept (D00742) 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[15] 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬

Disease ID	Name
15	Inclusion body myositis
35	Pemphigus
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
53	Sjogren syndrome
56	Behcet disease
60	Aplastic anemia
85	Idiopathic interstitial pneumonia
107	Juvenile idiopathic arthritis
228	Bronchiolitis obliterans
270	Chronic recurrent multifocal osteomyelitis
271	Ankylosing spondylitis
285	Fanconi anemia

Etanercept (50mg per week)
(D00742)

[1] Etanercept

[1] Etanercept (D00742) 💬

Name	Other Names
Etanercept	Etanercept (USAN/INN) Etanercept (genetical recombination) (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN) Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN) Enbrel (TN)

[2] LTA,
TNF 💬

[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...

[1] 271 💬

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