Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Riboflavin 💬[1] Riboflavin[2] Riboflavin; Vitamin B2--[7] 38, 46, 96, 97, 162, 168, 265 💬
2 Didanosine 💬[1] Didanosine[1] Didanosine--[2] 25, 265 💬
3 Lamivudine 💬[1] Lamivudine[4] COMBIVIR; Epivir; Lamivudine; Triumeq--[7] 2, 26, 42, 46, 135, 265, 325 💬
4 Zidovudine 💬[1] Zidovudine[3] COMBIVIR; Retrovir; Zidovudine--[6] 25, 26, 135, 265, 325, 331 💬
5 Ritonavir 💬[1] Ritonavir[2] Norvir; Ritonavir--[3] 2, 86, 265 💬
6 Saquinavir 💬[1] Saquinavir[1] Saquinavir--[2] 86, 265 💬
7 Simvastatin 💬[1] Simvastatin[3] Simvastatin; Simvastatina; Simvastatine[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
8 Nevirapine 💬[1] Nevirapine[1] Nevirapine--[1] 265 💬
9 Stavudine 💬[1] Stavudine[1] Stavudine--[1] 265 💬
10 Pyrimethamine 💬[1] Pyrimethamine[2] Daraprim; Pyrimethamine--[4] 2, 4, 19, 65 💬
11 Caffeine 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
12 Fenofibrate 💬[1] Fenofibrate[1] Fenofibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
13 Amprenavir 💬[1] Amprenavir[1] Amprenavir--[1] 265 💬
14 Efavirenz 💬[1] Efavirenz[2] Efavirenz; SUSTIVA--[1] 265 💬
15 Emtricitabine 💬[1] Emtricitabine[2] Emtricitabine; TRUVADA--[4] 25, 93, 265, 325 💬
16 Lopinavir 💬[1] Lopinavir[2] Kaletra; Lopinavir--[2] 93, 265 💬
17 Caffeine hydrate 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
18 Levocarnitine 💬[1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
19 Enfuvirtide 💬[1] Enfuvirtide[1] Enfuvirtide--[2] 25, 265 💬
20 Mecasermin 💬[1] Mecasermin[3] Increlex; Mecasermin; MECASERMINA[2] GHR,
IGF1R 💬 		[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[6] 65, 78, 96, 168, 265, 299 💬
21 Indinavir 💬[1] Indinavir[1] Indinavir--[1] 265 💬
22 Metformin 💬[1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
23 Metreleptin 💬[1] Metreleptin[3] METRELEPTIN; Myalept; R-metHuLeptin[1] LEPR 💬 [6] AMPK signaling pathway, Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease 💬[1] 265 💬
24 Pegvisomant 💬[1] Pegvisomant[1] Pegvisomant[1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[2] 78, 265 💬
25 Tenofovir 💬[1] Tenofovir[1] Tenofovir--[6] 2, 13, 25, 93, 265, 325 💬
26 Tesamorelin 💬[1] Tesamorelin[2] GHRH; Tesamorelin[1] GHRHR 💬 [2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265 💬
27 Raltegravir 💬[1] Raltegravir[2] ISENTRESS; Raltegravir--[4] 13, 26, 93, 265 💬
28 Abacavir 💬[1] Abacavir[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen--[4] 2, 135, 265, 325 💬
29 Acipimox 💬[1] Acipimox[1] Acipimox--[2] 78, 265 💬
30 Atazanavir 💬[1] Atazanavir[2] Atazanavir; Reyataz--[1] 265 💬
31 Atorvastatin 💬[1] Atorvastatin[3] Atorvastatin; Atorvastatin Calcium; Lipitor[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
32 Diosmin 💬[1] Diosmin[1] Diosmin--[3] 46, 97, 265 💬
33 Nelfinavir 💬[1] Nelfinavir[1] Nelfinavir--[3] 49, 265, 331 💬
34 Pioglitazone 💬[1] Pioglitazone[1] Pioglitazone[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
35 Pravastatin 💬[1] Pravastatin[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
36 Rosiglitazone 💬[1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265 💬
37 Thiamine 💬[1] Thiamine[2] Thiamine; Vitamin B1--[4] 8, 93, 145, 265 💬
38 Tipranavir 💬[1] Tipranavir[1] Tipranavir--[1] 265 💬
39 Obeticholic acid 💬[1] Obeticholic acid[4] 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva[1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
40 Dolutegravir 💬[1] Dolutegravir[2] Dolutegravir; Triumeq--[2] 2, 265 💬
41 Baricitinib 💬[1] Baricitinib[2] Baricitinib; OLUMIANT[2] JAK1,
JAK2 💬 		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
42 Doravirine 💬[1] Doravirine[1] Doravirine--[1] 265 💬
43 Cholic acid 💬[1] Cholic Acid[1] Cholic Acid[1] NR1H4 💬 [1] Bile secretion 💬[4] 20, 234, 265, 310 💬
44 Volanesorsen 💬[1] Volanesorsen[1] Volanesorsen[1] APOC3 💬 [2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265 💬
45 Setmelanotide 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 202, 265 💬