266. 家族性地中海熱 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 28 / 薬物数 : 22 - (DrugBank : 5) / 標的遺伝子数 : 14 - 標的パスウェイ数 : 59
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
ACZ885
Novartis Farma SpA
2014 Phase 3 EUCTR2013-004291-35-IT Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Farmacéutica, S.A.
2014 Phase 3 EUCTR2013-004291-35-ES Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharma Services AG
2014 Phase 3 EUCTR2013-004291-35-NL Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-IE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-HU Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-GR Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-BE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharmaceuticals
- - EUCTR2015-003527-57-Outside-EU/EEA Turkey;
- - EUCTR2015-003522-13-Outside-EU/EEA Israel;
ACZ885, 150mg/1.0ml
Novartis Pharma Services AG
2014 Phase 3 EUCTR2013-004291-35-DE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Canakinumab
Novartis Pharmaceuticals
2010 Phase 2 NCT01148797 Israel;
2010 Phase 2 NCT01088880 Turkey;
Colchicine
Gulhane Military Medical Academy
2011 Phase 4 NCT02602028 Turkey;
Rambam Health Care Campus
2014 Phase 2 NCT02175589 Israel;
Sheba Medical Center
2017 - NCT03210610 Israel;
Colchicine sprinkle capsules
Mutual Pharmaceutical Company, Inc.
2010 Phase 1 NCT01075906 Armenia;Israel;Turkey;United States;
IL-1 Trap
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
2004 Phase 2 NCT00094900 United States;
INN-Tocilizumab
University Hospital Tuebingen
2017 Phase 2 EUCTR2016-004505-13-DE Germany;
Ilaris
Novartis Farma SpA
2014 Phase 3 EUCTR2013-004291-35-IT Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Farmacéutica, S.A.
2014 Phase 3 EUCTR2013-004291-35-ES Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharma Services AG
2014 Phase 3 EUCTR2013-004291-35-NL Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-DE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharmaceuticals
- - EUCTR2015-003527-57-Outside-EU/EEA Turkey;
- - EUCTR2015-003522-13-Outside-EU/EEA Israel;
Novartis pharma AG
- Phase 3 EUCTR2017-001678-40-Outside-EU/EEA Japan;
Kineret
Sheba Medical Center
2012 Phase 3 NCT01705756 Israel;
One additional blood sample during a planned blood test
Hospices Civils de Lyon
2021 - NCT04478409 France;
Probiotic
Rambam Health Care Campus
2013 - NCT02021084 -
RPH-104
R-Pharm International, LLC
2021 Phase 2 NCT05190991 Armenia;Georgia;Russian Federation;
Rilonacept
The Cleveland Clinic
2008 Phase 2 NCT00582907 United States;
RoActemra® 20mg/ml Konzentrat
University Hospital Tuebingen
2017 Phase 2 EUCTR2016-004505-13-DE Germany;
Tocilizumab
Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
2018 - JPRN-UMIN000032557 Japan;
2018 - JPRN-UMIN000028010 Japan;
Tocilizumab Infusion RoAcemtra (EU)
University Hospital Tuebingen
2018 Phase 2 NCT03446209 Germany;
Wheat
University of Palermo
2018 - NCT03563300 Italy;
physiological saline
University Hospital Tuebingen
2018 Phase 2 NCT03446209 Germany;
Novartis Farma SpA
2014 Phase 3 EUCTR2013-004291-35-IT Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Farmacéutica, S.A.
2014 Phase 3 EUCTR2013-004291-35-ES Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharma Services AG
2014 Phase 3 EUCTR2013-004291-35-NL Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-IE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-HU Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-GR Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-BE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharmaceuticals
- - EUCTR2015-003527-57-Outside-EU/EEA Turkey;
- - EUCTR2015-003522-13-Outside-EU/EEA Israel;
ACZ885, 150mg/1.0ml
Novartis Pharma Services AG
2014 Phase 3 EUCTR2013-004291-35-DE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Canakinumab
Novartis Pharmaceuticals
2010 Phase 2 NCT01148797 Israel;
2010 Phase 2 NCT01088880 Turkey;
Colchicine
Gulhane Military Medical Academy
2011 Phase 4 NCT02602028 Turkey;
Rambam Health Care Campus
2014 Phase 2 NCT02175589 Israel;
Sheba Medical Center
2017 - NCT03210610 Israel;
Colchicine sprinkle capsules
Mutual Pharmaceutical Company, Inc.
2010 Phase 1 NCT01075906 Armenia;Israel;Turkey;United States;
IL-1 Trap
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
2004 Phase 2 NCT00094900 United States;
INN-Tocilizumab
University Hospital Tuebingen
2017 Phase 2 EUCTR2016-004505-13-DE Germany;
Ilaris
Novartis Farma SpA
2014 Phase 3 EUCTR2013-004291-35-IT Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Farmacéutica, S.A.
2014 Phase 3 EUCTR2013-004291-35-ES Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharma Services AG
2014 Phase 3 EUCTR2013-004291-35-NL Belgium;Canada;Denmark;Finland;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
2014 Phase 3 EUCTR2013-004291-35-DE Belgium;Canada;France;Germany;Greece;Hungary;Ireland;Israel;Italy;Japan;Netherlands;Russian Federation;Spain;Switzerland;Turkey;United Kingdom;United States;
Novartis Pharmaceuticals
- - EUCTR2015-003527-57-Outside-EU/EEA Turkey;
- - EUCTR2015-003522-13-Outside-EU/EEA Israel;
Novartis pharma AG
- Phase 3 EUCTR2017-001678-40-Outside-EU/EEA Japan;
Kineret
Sheba Medical Center
2012 Phase 3 NCT01705756 Israel;
One additional blood sample during a planned blood test
Hospices Civils de Lyon
2021 - NCT04478409 France;
Probiotic
Rambam Health Care Campus
2013 - NCT02021084 -
RPH-104
R-Pharm International, LLC
2021 Phase 2 NCT05190991 Armenia;Georgia;Russian Federation;
Rilonacept
The Cleveland Clinic
2008 Phase 2 NCT00582907 United States;
RoActemra® 20mg/ml Konzentrat
University Hospital Tuebingen
2017 Phase 2 EUCTR2016-004505-13-DE Germany;
Tocilizumab
Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences
2018 - JPRN-UMIN000032557 Japan;
2018 - JPRN-UMIN000028010 Japan;
Tocilizumab Infusion RoAcemtra (EU)
University Hospital Tuebingen
2018 Phase 2 NCT03446209 Germany;
Wheat
University of Palermo
2018 - NCT03563300 Italy;
physiological saline
University Hospital Tuebingen
2018 Phase 2 NCT03446209 Germany;