76. 下垂体性ゴナドトロピン分泌亢進症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 29 / 薬物数 : 44 - (DrugBank : 14) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 15
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
Acetate
Hospital de Niños R. Gutierrez de Buenos Aires
2009 Phase 3 NCT01278290 Argentina;
CPP
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
2020 Phase 0 ChiCTR2000034464 China;
Dabu ying pills
Ruijin Hospital
2012 Phase 4 NCT02920515 -
Enantone
Takeda
2017 - NCT02993926 China;
Estradiol
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
GnRH agonist
Takeda
2017 - NCT02993926 China;
Gold
Capital Institute of Pediatrics
2020 - ChiCTR2000038202 China;
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
2020 Phase 0 ChiCTR2000034464 China;
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
Gonadorelin
Hospital de Niños R. Gutierrez de Buenos Aires
2009 Phase 3 NCT01278290 Argentina;
Histrelin Subcutaneous Implant
Endo Pharmaceuticals
2004 Phase 3 NCT00779103 -
LEUPRORELIN ACETATE
Abbvie previously known as Abbott
- - EUCTR2014-004495-36-Outside-EU/EEA United States;
- - EUCTR2014-004494-16-Outside-EU/EEA Puerto Rico;United States;
Abbvie previously known as Abbott
- - EUCTR2014-004493-42-Outside-EU/EEA Puerto Rico;United States;
Leuplin DPS
Jin Soon Hwang
2015 Phase 4 NCT03316482 Korea, Republic of;
Leuprolide
Kyungpook National University
2016 Phase 4 NCT02974270 Korea, Republic of;
Nemours Children's Clinic
2016 Phase 3 NCT02811471 United States;
Leuprolide (GnRH agonists)
University of Pisa
2006 Phase 4 NCT00438217 Italy;
Leuprolide Acetate
Tolmar Inc.
2015 Phase 3 NCT02452931 Argentina;Canada;Chile;Mexico;New Zealand;United States;
Leuprolide Acetate (LA)
AbbVie
2018 Phase 3 NCT03695237 Puerto Rico;United States;
Leuprolide Acetate 3 Month Depot
AbbVie (prior sponsor, Abbott)
2008 Phase 3 NCT00667446 Puerto Rico;United States;
Leuprolide acetate
Abbott
2008 Phase 3 NCT00635817 Puerto Rico;United States;
Leuprolide acetate depot
Abbvie previously known as Abbott
- - EUCTR2014-004493-42-Outside-EU/EEA Puerto Rico;United States;
Leuprorelin
Takeda
2015 Phase 4 NCT02427958 China;
Leuprorelin Acetate 3.75mg Injection
Children's Hospital of Fudan University
2019 Phase 4 NCT03963752 China;
Luphere depot 3.75mg(Leuprolide acetate 3.75mg)
Daewoong Pharmaceutical Co. LTD.
2011 Phase 4 NCT01634321 Korea, Republic of;
Lupron (leuprolide acetate)
Abbott
1991 Phase 3 NCT00660010 United States;
Megestrol Acetate Tablet
Children's Hospital of Fudan University
2019 Phase 4 NCT03963752 China;
Progesterone
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
RhGH
The Children's Hospital, Zhe Jiang University School of Medcine
2018 - ChiCTR1800016768 China;
The Children's Hospital, Zhejiang University School of Medicine
2018 - ChiCTR1800017120 China;
Testosterone
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
Trade name depends on the source of the product
Abbvie previously known as Abbott
- - EUCTR2014-004495-36-Outside-EU/EEA United States;
Abbvie previously known as Abbott
- - EUCTR2014-004493-42-Outside-EU/EEA Puerto Rico;United States;
Trade name depends on the source of the product’
Abbvie previously known as Abbott
- - EUCTR2014-004494-16-Outside-EU/EEA Puerto Rico;United States;
Triptorelin
Debiopharm International SA
2012 Phase 3 NCT01467882 Chile;Mexico;United States;
Hospital de Niños R. Gutierrez de Buenos Aires
2009 Phase 3 NCT01278290 Argentina;
Triptorelin (GnRH agonists)
University of Pisa
2006 Phase 4 NCT00438217 Italy;
Triptorelin Pamoate
Ipsen
2021 Phase 3 NCT05029622 China;
Triptorelin embonate, Triptorelin pamoate
Debiopharm International, S.A.
- - EUCTR2015-001607-30-Outside-EU/EEA Chile;Mexico;United States;
Triptorelin pamoate
Ipsen
2021 Phase 3 NCT04736602 China;
Triptorlin or Leuprorelin
Ruijin Hospital
2012 Phase 4 NCT02920515 -
Zhibo dihuang pills
Ruijin Hospital
2012 Phase 4 NCT02920515 -
Ziyinxiehuo Granules Herbs
Children's Hospital of Fudan University
2019 Phase 4 NCT03963752 China;
Hospital de Niños R. Gutierrez de Buenos Aires
2009 Phase 3 NCT01278290 Argentina;
CPP
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
2020 Phase 0 ChiCTR2000034464 China;
Dabu ying pills
Ruijin Hospital
2012 Phase 4 NCT02920515 -
Enantone
Takeda
2017 - NCT02993926 China;
Estradiol
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
GnRH agonist
Takeda
2017 - NCT02993926 China;
Gold
Capital Institute of Pediatrics
2020 - ChiCTR2000038202 China;
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
2020 Phase 0 ChiCTR2000034464 China;
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
Gonadorelin
Hospital de Niños R. Gutierrez de Buenos Aires
2009 Phase 3 NCT01278290 Argentina;
Histrelin Subcutaneous Implant
Endo Pharmaceuticals
2004 Phase 3 NCT00779103 -
LEUPRORELIN ACETATE
Abbvie previously known as Abbott
- - EUCTR2014-004495-36-Outside-EU/EEA United States;
- - EUCTR2014-004494-16-Outside-EU/EEA Puerto Rico;United States;
Abbvie previously known as Abbott
- - EUCTR2014-004493-42-Outside-EU/EEA Puerto Rico;United States;
Leuplin DPS
Jin Soon Hwang
2015 Phase 4 NCT03316482 Korea, Republic of;
Leuprolide
Kyungpook National University
2016 Phase 4 NCT02974270 Korea, Republic of;
Nemours Children's Clinic
2016 Phase 3 NCT02811471 United States;
Leuprolide (GnRH agonists)
University of Pisa
2006 Phase 4 NCT00438217 Italy;
Leuprolide Acetate
Tolmar Inc.
2015 Phase 3 NCT02452931 Argentina;Canada;Chile;Mexico;New Zealand;United States;
Leuprolide Acetate (LA)
AbbVie
2018 Phase 3 NCT03695237 Puerto Rico;United States;
Leuprolide Acetate 3 Month Depot
AbbVie (prior sponsor, Abbott)
2008 Phase 3 NCT00667446 Puerto Rico;United States;
Leuprolide acetate
Abbott
2008 Phase 3 NCT00635817 Puerto Rico;United States;
Leuprolide acetate depot
Abbvie previously known as Abbott
- - EUCTR2014-004493-42-Outside-EU/EEA Puerto Rico;United States;
Leuprorelin
Takeda
2015 Phase 4 NCT02427958 China;
Leuprorelin Acetate 3.75mg Injection
Children's Hospital of Fudan University
2019 Phase 4 NCT03963752 China;
Luphere depot 3.75mg(Leuprolide acetate 3.75mg)
Daewoong Pharmaceutical Co. LTD.
2011 Phase 4 NCT01634321 Korea, Republic of;
Lupron (leuprolide acetate)
Abbott
1991 Phase 3 NCT00660010 United States;
Megestrol Acetate Tablet
Children's Hospital of Fudan University
2019 Phase 4 NCT03963752 China;
Progesterone
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
RhGH
The Children's Hospital, Zhe Jiang University School of Medcine
2018 - ChiCTR1800016768 China;
The Children's Hospital, Zhejiang University School of Medicine
2018 - ChiCTR1800017120 China;
Testosterone
The Children's Hospital, Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2100047299 China;
Trade name depends on the source of the product
Abbvie previously known as Abbott
- - EUCTR2014-004495-36-Outside-EU/EEA United States;
Abbvie previously known as Abbott
- - EUCTR2014-004493-42-Outside-EU/EEA Puerto Rico;United States;
Trade name depends on the source of the product’
Abbvie previously known as Abbott
- - EUCTR2014-004494-16-Outside-EU/EEA Puerto Rico;United States;
Triptorelin
Debiopharm International SA
2012 Phase 3 NCT01467882 Chile;Mexico;United States;
Hospital de Niños R. Gutierrez de Buenos Aires
2009 Phase 3 NCT01278290 Argentina;
Triptorelin (GnRH agonists)
University of Pisa
2006 Phase 4 NCT00438217 Italy;
Triptorelin Pamoate
Ipsen
2021 Phase 3 NCT05029622 China;
Triptorelin embonate, Triptorelin pamoate
Debiopharm International, S.A.
- - EUCTR2015-001607-30-Outside-EU/EEA Chile;Mexico;United States;
Triptorelin pamoate
Ipsen
2021 Phase 3 NCT04736602 China;
Triptorlin or Leuprorelin
Ruijin Hospital
2012 Phase 4 NCT02920515 -
Zhibo dihuang pills
Ruijin Hospital
2012 Phase 4 NCT02920515 -
Ziyinxiehuo Granules Herbs
Children's Hospital of Fudan University
2019 Phase 4 NCT03963752 China;