21. Mitochondrial disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 39 / Drugs : 42 - (DrugBank : 32) / Drug target genes : 47 - Drug target pathways : 67
Mitochondrial disease and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
| ID | Diseases (Sorted by drug repositionability) |
|---|---|
| 21 | Mitochondrial disease |
| 6 | Parkinson disease |
| 13 | Multiple sclerosis/Neuromyelitis optica |
| 96 | Crohn disease |
| 46 | Malignant rheumatoid arthritis |
| 2 | Amyotrophic lateral sclerosis |
| 97 | Ulcerative colitis |
| 8 | Huntington disease |
| 206 | Fragile X syndrome |
| 70 | Spinal stenosis |
| 5 | Progressive supranuclear palsy |
| 17 | Multiple system atrophy |
| 205 | Fragile X syndrome related disease |
| 22 | Moyamoya disease |
| 78 | Hypopituitarism |
| 18 | Spinocerebellar degeneration |
| 156 | Rett syndrome |
| 3 | Spinal muscular atrophy |
| 152 | PCDH19 related syndrome |
| 84 | Sarcoidosis |
| 201 | Angelman syndrome |
| 34 | Neurofibromatosis |
| 145 | West syndrome |
| 298 | Hereditary pancreatitis |
| 231 | Alpha-1-antitrypsin deficiency |
| 158 | Tuberous sclerosis |
| 272 | Fibrodysplasia ossificans progressiva |
| 193 | Prader-Willi syndrome |
| 98 | Eosinophilic gastrointestinal disease |
| 155 | Acquired aphasia with convulsive disorder |
| 140 | Dorabe syndrome |
| 296 | Biliary atresia |
| 75 | Cushing disease |
| 299 | Cystic fibrosis |
| 144 | Lennox-Gastaut syndrome |
| 36 | Epidermolysis bullosa |
| 113 | Muscular dystrophy |
| 226 | Interstitial cystitis with Hunners ulcer |
| 265 | Lipodystrophy |
| 236 | Pseudohypoparathyroidism |
| 179 | Williams syndrome |
| 4 | Primary lateral sclerosis |
| 294 | Congenital diaphragmatic hernia |
| 63 | Idiopathic thrombocytopenic purpura |
| 246 | Methylmalonic acidemia |
| 107 | Juvenile idiopathic arthritis |
| 215 | Tetralogy of Fallot |
| 171 | Wilson disease |
| 323 | Aromatic L-amino acid decarboxylase deficiency |
| 51 | Scleroderma |
| 49 | Systemic lupus erythematosus |
| 271 | Ankylosing spondylitis |
| 65 | Primary immunodeficiency |
| 85 | Idiopathic interstitial pneumonia |
| 212 | Tricuspid atresia |
| 203 | 22q11.2 deletion syndrome |
| 127 | Frontotemporal lobar degeneration |
| 337 | Homocystinuria |
| 282 | Congenital dyserythropoietic anemia |
| 254 | Porphyria |
| 187 | Kabuki syndrome |
| 225 | Congenital nephrogenic diabetes insipidus |
| 118 | Myelomeningocele |
| 169 | Menkes disease |
| 170 | Occipital horn syndrome |
| 86 | Pulmonary arterial hypertension |
| 251 | Urea cycle disorder |
| 71 | Idiopathic osteonecrosis of the femoral head |
| 11 | Myasthenia gravis |