4. Primary lateral sclerosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 5 / Drugs : 13 - (DrugBank : 6) / Drug target genes : 13 - Drug target pathways : 25
Primary lateral sclerosis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
ID | Diseases (Sorted by drug repositionability) |
---|---|
4 | Primary lateral sclerosis |
6 | Parkinson disease |
2 | Amyotrophic lateral sclerosis |
13 | Multiple sclerosis/Neuromyelitis optica |
17 | Multiple system atrophy |
8 | Huntington disease |
206 | Fragile X syndrome |
5 | Progressive supranuclear palsy |
215 | Tetralogy of Fallot |
21 | Mitochondrial disease |
90 | Retinitis pigmentosa |
3 | Spinal muscular atrophy |
70 | Spinal stenosis |
46 | Malignant rheumatoid arthritis |
78 | Hypopituitarism |
309 | Progressive myoclonus epilepsy |
113 | Muscular dystrophy |
96 | Crohn disease |
12 | Congenital myasthenic syndrome |
7 | Corticobasal degeneration |
127 | Frontotemporal lobar degeneration |
11 | Myasthenia gravis |
201 | Angelman syndrome |
323 | Aromatic L-amino acid decarboxylase deficiency |
97 | Ulcerative colitis |
203 | 22q11.2 deletion syndrome |
164 | Oculocutaneous albinism |
74 | Prolactin secreting pituitary adenoma |
140 | Dorabe syndrome |
156 | Rett syndrome |
205 | Fragile X syndrome related disease |
14 | Chronic inflammatory demyelinating polyneuropathy |
18 | Spinocerebellar degeneration |
299 | Cystic fibrosis |
254 | Porphyria |
85 | Idiopathic interstitial pneumonia |
49 | Systemic lupus erythematosus |
212 | Tricuspid atresia |
118 | Myelomeningocele |
169 | Menkes disease |
170 | Occipital horn syndrome |
280 | Huge arteriovenous malformation with cervicofacial or limb lesion |