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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
ADRA2A
💬
1. ADRA2A
×
Name
Full Name
ADRA2A
adrenoceptor alpha 2A
[2]
cGMP-PKG signaling pathway
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
Dexmedetomidine
Dexmedetomidine
💬
1. ADRA2A
×
Name
Other Names
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexdor (TN)
Precedex (TN)
Dexmedetomidine
[14]
2
2
,
4
,
6
,
21
,
34
,
46
,
70
,
107
,
113
,
171
,
212
,
215
,
226
,
280
💬
1. ADRA2A
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
6
Parkinson disease
21
Mitochondrial disease
34
Neurofibromatosis
46
Malignant rheumatoid arthritis
70
Spinal stenosis
107
Juvenile idiopathic arthritis
113
Muscular dystrophy
171
Wilson disease
212
Tricuspid atresia
215
Tetralogy of Fallot
226
Interstitial cystitis with Hunners ulcer
280
Huge arteriovenous malformation with cervicofacial or limb lesion
2
ADRA2B
💬
2. ADRA2B
×
Name
Full Name
ADRA2B
adrenoceptor alpha 2B
[2]
cGMP-PKG signaling pathway
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
Dexmedetomidine
Dexmedetomidine
💬
2. ADRA2B
×
Name
Other Names
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexdor (TN)
Precedex (TN)
Dexmedetomidine
[14]
2
2
,
4
,
6
,
21
,
34
,
46
,
70
,
107
,
113
,
171
,
212
,
215
,
226
,
280
💬
2. ADRA2B
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
6
Parkinson disease
21
Mitochondrial disease
34
Neurofibromatosis
46
Malignant rheumatoid arthritis
70
Spinal stenosis
107
Juvenile idiopathic arthritis
113
Muscular dystrophy
171
Wilson disease
212
Tricuspid atresia
215
Tetralogy of Fallot
226
Interstitial cystitis with Hunners ulcer
280
Huge arteriovenous malformation with cervicofacial or limb lesion
3
ADRA2C
💬
3. ADRA2C
×
Name
Full Name
ADRA2C
adrenoceptor alpha 2C
[2]
cGMP-PKG signaling pathway
cGMP-PKG signaling pathway
,
Neuroactive ligand-receptor interaction
Dexmedetomidine
Dexmedetomidine
💬
3. ADRA2C
×
Name
Other Names
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexdor (TN)
Precedex (TN)
Dexmedetomidine
[14]
2
2
,
4
,
6
,
21
,
34
,
46
,
70
,
107
,
113
,
171
,
212
,
215
,
226
,
280
💬
3. ADRA2C
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
6
Parkinson disease
21
Mitochondrial disease
34
Neurofibromatosis
46
Malignant rheumatoid arthritis
70
Spinal stenosis
107
Juvenile idiopathic arthritis
113
Muscular dystrophy
171
Wilson disease
212
Tricuspid atresia
215
Tetralogy of Fallot
226
Interstitial cystitis with Hunners ulcer
280
Huge arteriovenous malformation with cervicofacial or limb lesion
4
GRIN1
💬
4. GRIN1
×
Name
Full Name
GRIN1
glutamate ionotropic receptor NMDA type subunit 1
[18]
Ras signaling pathway
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
[18]
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathwa
...
Esketamine
Esketamine
💬
4. GRIN1
×
Name
Other Names
Esketamine
Esketamine (USAN/INN)
Esketamine
[3]
2
2
,
4
,
70
💬
4. GRIN1
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
70
Spinal stenosis
5
GRIN1
💬
5. GRIN1
×
Name
Full Name
GRIN1
glutamate ionotropic receptor NMDA type subunit 1
[18]
Ras signaling pathway
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
[18]
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathwa
...
Ketamine
Ketamine
💬
5. GRIN1
×
Name
Other Names
Ketamine
Ketamine (INN)
Tekam (TN)
Ketamine
[8]
2
2
,
4
,
6
,
13
,
70
,
113
,
156
,
215
💬
5. GRIN1
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
70
Spinal stenosis
113
Muscular dystrophy
156
Rett syndrome
215
Tetralogy of Fallot
6
GRIN2A
💬
6. GRIN2A
×
Name
Full Name
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
[19]
Ras signaling pathway
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Dopaminergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
,
Systemic lupus erythematosus
[19]
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathwa
...
Esketamine
Esketamine
💬
6. GRIN2A
×
Name
Other Names
Esketamine
Esketamine (USAN/INN)
Esketamine
[3]
2
2
,
4
,
70
💬
6. GRIN2A
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
70
Spinal stenosis
7
GRIN2A
💬
7. GRIN2A
×
Name
Full Name
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
[19]
Ras signaling pathway
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Dopaminergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
,
Systemic lupus erythematosus
[19]
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
cAMP signaling pathwa
...
Ketamine
Ketamine
💬
7. GRIN2A
×
Name
Other Names
Ketamine
Ketamine (INN)
Tekam (TN)
Ketamine
[8]
2
2
,
4
,
6
,
13
,
70
,
113
,
156
,
215
💬
7. GRIN2A
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
70
Spinal stenosis
113
Muscular dystrophy
156
Rett syndrome
215
Tetralogy of Fallot
8
GRIN2B
💬
8. GRIN2B
×
Name
Full Name
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
[19]
Ras signaling pathway
Ras signaling pathway
,
Rap1 signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Dopaminergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
,
Systemic lupus erythematosus
[19]
Ras signaling pathway
,
Rap1 signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-recep
...
Esketamine
Esketamine
💬
8. GRIN2B
×
Name
Other Names
Esketamine
Esketamine (USAN/INN)
Esketamine
[3]
2
2
,
4
,
70
💬
8. GRIN2B
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
70
Spinal stenosis
9
GRIN2B
💬
9. GRIN2B
×
Name
Full Name
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
[19]
Ras signaling pathway
Ras signaling pathway
,
Rap1 signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Dopaminergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
,
Systemic lupus erythematosus
[19]
Ras signaling pathway
,
Rap1 signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-recep
...
Ketamine
Ketamine
💬
9. GRIN2B
×
Name
Other Names
Ketamine
Ketamine (INN)
Tekam (TN)
Ketamine
[8]
2
2
,
4
,
6
,
13
,
70
,
113
,
156
,
215
💬
9. GRIN2B
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
70
Spinal stenosis
113
Muscular dystrophy
156
Rett syndrome
215
Tetralogy of Fallot
10
GRIN2C
💬
10. GRIN2C
×
Name
Full Name
GRIN2C
glutamate ionotropic receptor NMDA type subunit 2C
[15]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Circadian entrainment
,
Long-term potentiation
,
Glutamatergic synapse
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Spinocerebellar ataxia
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Cocaine addiction
,
Amphetamine addiction
,
Nicotine addiction
,
Alcoholism
[15]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Cir
...
Esketamine
Esketamine
💬
10. GRIN2C
×
Name
Other Names
Esketamine
Esketamine (USAN/INN)
Esketamine
[3]
2
2
,
4
,
70
💬
10. GRIN2C
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
4
Primary lateral sclerosis
70
Spinal stenosis