VPA

( DrugBank: - / KEGG DRUG: - )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
3	脊髄性筋萎縮症	5

3. 脊髄性筋萎縮症

臨床試験数 : 237 / 薬物数 : 123 - (DrugBank : 29) / 標的遺伝子数 : 51 - 標的パスウェイ数 : 75

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Showing 1 to 5 of 5 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JMA-IIA00259	16/08/2016	10/08/2016	Multicenter cooperative and investigator initiated clinical trial using valproic acid in childhood o ...	Multicenter cooperative and investigator initiated clinical trial using valproic acid in childhood o ...	spinal muscular atrophy	Intervention type:DRUG. Intervention1:SMART, Dose form:GRANULES, Route of administration:ORAL, inten ...	Institute of Medical Genetics, Tokyo Women's Medical University	NULL	Recruiting	>=1 YEARS	<8 YEARS	BOTH	28	Phase 2B	Japan
2	JPRN-JMA-IIA00231	29/01/2016	01/12/2015	Multicenter cooperative and investigator initiated clinical trial using valproic acid in childhood o ...	Multicenter cooperative and investigator initiated clinical trial using valproic acid in childhood o ...	spinal muscular atrophy	Intervention type:DRUG. Intervention1:SMART, Dose form:GRANULES, Route of administration:ORAL, inten ...	Institute of Medical Genetics, Tokyo Women's Medical University	NULL	Completed	>=1 YEARS	<7 YEARS	BOTH	28	Phase 2B	Japan
3	JPRN-JMA-IIA00190	22/07/2014	01/08/2014	Multicenter cooperative and investigator initiated clinical trial using valproic acid in childhood o ...	Multicenter cooperative and investigator initiated clinical trial using valproic acid in childhood o ...	spinal muscular atrophy	Intervention type:DRUG. Intervention1:SMART, Dose form:GRANULES, Route of administration:ORAL, inten ...	Institute of Medical Genetics, Tokyo Women's Medical University	NULL	Completed	No Limit	<8 YEARS	BOTH	13	Phase 2A	Japan
4	NCT00481013 (ClinicalTrials.gov)	July 2007	30/5/2007	Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy	Prospective Controlled Trial of Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy (VALIA ...	Spinal Muscular Atrophy	Drug: Valproic Acid (VPA);Drug: Placebo	University of Utah	Families of Spinal Muscular Atrophy;Abbott	Completed	18 Years	60 Years	Both	33	Phase 2	United States
5	NCT00374075 (ClinicalTrials.gov)	September 2003	6/9/2006	Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscu ...	In Vivo Study of Safety, Tolerability and Dosing Effect on SMN mRNA and Protein Levels of Valproic A ...	Spinal Muscular Atrophy	Drug: Valproic Acid	University of Utah	Families of Spinal Muscular Atrophy;Sigma Tau Pharmaceuticals, Inc.;Abbott	Completed	2 Years	N/A	Both	42	Phase 1	United States

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