Drug Description in Trials / DrugBank / KEGG DRUG

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No.	DrugBank	薬物名（臨床試験情報から抽出）	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Amiloride (Synonym: Amiloride Hydrochloride and Hydrochlorothiazide)	3件: AMILORIDE; Amiloride Hydrochloride; Midamor	1件: D07447	3件: SCNN1A, SCNN1B, SCNN1G 💬	2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬	4件: 13, 67, 225, 299
2	Amlodipine (Synonym: Olmesartan Medoxomil / Amlodipine Besylate / Hydrochlorothiazide)	1件: Amlodipine	1件: D07450	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, ...	4件: 13, 51, 67, 298
3	Benazepril (Synonym: Benazepril Hydrochloride and Hydrochlorothiazide)	1件: Benazepril	1件: D07499	1件: ACE 💬	6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...	4件: 49, 57, 218, 224
4	Bisoprolol (Synonym: Bisoprolol Fumarate and Hydrochlorothiazide)	2件: BISOPROLOL; Bisoprolol Fumarate	1件: D02342	1件: ADRB1 💬	11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - re ...	4件: 58, 67, 86, 113
5	Candesartan cilexetil (Synonym: Zinda-candesartan/hydrochlorothiazide)	1件: CANDESARTAN	1件: D00626	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, A ...	1件: 67
6	Captopril (Synonym: Captopril and Hydrochlorothiazide)	1件: Captopril	1件: D00251	1件: ACE 💬	6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...	8件: 6, 17, 46, 86, 96, 97, 107, 271
7	Enalapril (Synonym: Enalapril Maleate and Hydrochlorothiazide)	2件: ENALAPRIL; Enalapril Maleate	1件: D07892	1件: ACE 💬	6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyop ...	6件: 19, 46, 66, 113, 210, 222
8	Hydralazine (Synonym: Hydralazine HCl and Hydrochlorothiazide)	1件: Hydralazine	1件: D08044	1件: AOC3 💬	5件: Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine ...	1件: 67
9	Hydrochlorothiazide	2件: Esidrix; Hydrochlorothiazide	1件: D00340 (Name: Hydrochlorothiazide)	1件: SLC12A3 💬	-	4件: 13, 67, 225, 235
10	Irbesartan (Synonym: Irbesartan Hydrochlorothiazide Bms)	2件: Aprovel; IRBESARTAN	1件: D00523	1件: AGTR1 💬	16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, A ...	4件: 66, 167, 168, 222

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