Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Cabergoline 3件: CABERGOLINA; Cabergoline; DOSTINEX1件: D00987 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75
2 Cabotegravir 1件: Cabotegravir1件: D10548 --1件: 256
3 Cabozantinib 1件: Cabozantinib1件: D10062 3件: AXL,
KDR,
MET 💬		25件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, EGFR tyrosine kinase inhibitor resistance, Epithelial cell signaling in Helicobacter pylori infection, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, Hepatocellular carcinoma, MAPK signaling pathway, Malaria, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Renal cell carcinoma, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 34
4 Caffeine 1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
5 Calcifediol 2件: 25-Hydroxyvitamin D3; CALCIFEDIOL1件: D00122 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 113, 299
6 Calcipotriol 2件: Calcipotriene; CALCIPOTRIOL1件: D01125 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 36, 51
7 Calcitriol 1件: Calcitriol1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬9件: 18, 37, 46, 49, 66, 96, 158, 235, 326
8 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
9 Calcium carbonate 3件: Calcio carbonato; Calcium; Calcium carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
10 Calcium citrate 1件: Calcium Citrate1件: D00933 --3件: 46, 84, 235
11 Calcium gluconate 1件: Calcium gluconate1件: D00935 --3件: 214, 215, 235
12 Calcium lactate 1件: Calcium lactate2件: D00936 ,
D02254 		--1件: 235
13 Calfactant 1件: Calfactant1件: D03317 --1件: 299
14 Calusterone 0件: 1件: D03338 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 2
15 Canakinumab 2件: Canakinumab; ILARIS1件: D09315 1件: IL1B 💬44件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
16 Candesartan 1件: Candesartan1件: D00522 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 58, 67
17 Candesartan cilexetil 1件: CANDESARTAN1件: D00626 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 67
18 Cannabidiol 4件: CANNABIDIOL; Epidiolex; Epidyolex; Sativex1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
19 Cannabidivarin 1件: CBDV---1件: 193
20 Cannabinol 1件: CANNABINOL---1件: 36
21 CAP-1002 1件: CAP-1002---1件: 113
22 Caplacizumab 2件: CABLIVI; CAPLACIZUMAB1件: D11160 1件: VWF 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬1件: 64
23 Capsaicin 2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
24 Captopril 1件: Captopril1件: D00251 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
25 Carbamazepine 1件: Carbamazepine1件: D00252 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 6, 13, 231
26 Carbaspirin calcium 1件: Carbasalate calcium1件: D03385 --1件: 46
27 Carbidopa 8件: Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201
28 Carbomer 2件: Carbomer; Lacryvisc---1件: 53
29 Carbon dioxide 1件: Carbon dioxide1件: D00004 --2件: 97, 158
30 Carbon monoxide 1件: Carbon Monoxide1件: D09706 --4件: 13, 53, 85, 86
31 Carbonate ion 1件: Carbonate---12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
32 Carboplatin 2件: Carboplatin; CBDCA1件: D01363 --4件: 28, 34, 60, 85
33 Carbopol 974P 1件: Carbomer 974P---1件: 53
34 Carfilzomib 1件: Carfilzomib1件: D08880 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬1件: 28
35 Carglumic acid 3件: Carbaglu; Carglumic acid; N-Carbamylglutamate1件: D07130 1件: CPS1 💬6件: Alanine, aspartate and glutamate metabolism, Arginine biosynthesis, Biosynthesis of amino acids, Carbon metabolism, Metabolic pathways, Nitrogen metabolism 💬3件: 245, 246, 251
36 Cariprazine 1件: Reagila1件: D09997 3件: DRD2,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 21
37 Carisbamate 1件: Carisbamate1件: D06573 --1件: 144
38 Carmustine 1件: Carmustine1件: D00254 --5件: 11, 13, 14, 28, 60
39 Carnosine 1件: Carnosine---2件: 6, 13
40 Carvedilol 1件: Carvedilol1件: D00255 5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 86, 113, 210
41 Casein 1件: Casein---1件: 97
42 Casimersen 1件: CASIMERSEN1件: D11988 1件: DMD 💬4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113
43 Caspofungin 2件: Caspofungin; CASPOFUNGIN ACETATE1件: D07626 --1件: 60
44 Catridecacog 1件: Catridecacog1件: D10532 --2件: 97, 288
45 Cavosonstat 1件: Cavosonstat1件: D10916 --1件: 299
46 CCX-140 0件: ---1件: 222
47 CCX-354 1件: CCX-354---1件: 46
48 CDP323 1件: CDP323---1件: 13
49 CE-VST01-JC 1件: CE-VST01-JC---1件: 25
50 Cediranib 1件: Cediranib1件: D08881 3件: FLT1,
FLT4,
KDR 💬		15件: Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 34
51 Cefadroxil 0件: 2件: D00257 ,
D02353 		--2件: 222, 240
52 Cefazolin 1件: Cefazolin1件: D02299 --1件: 291
53 Cefepime 1件: Cefepime1件: D02376 --2件: 60, 299
54 Cefiderocol 1件: Cefiderocol1件: D11302 --1件: 299
55 Cefoperazone 1件: Cefoperazone1件: D07645 --1件: 296
56 Ceftaroline fosamil 1件: Ceftaroline1件: D08884 --1件: 299
57 Ceftazidime 3件: Ceftazidim; Ceftazidima; CEFTAZIDIME2件: D00921 ,
D07654 		--1件: 299
58 Ceftolozane 1件: Ceftolozane1件: D10097 --1件: 299
59 Ceftriaxone 1件: CEFTRIAXONE1件: D07659 --4件: 2, 6, 46, 97
60 Cefuroxime 2件: Cefuroxim; Cefuroxime1件: D00262 --2件: 97, 299
61 Celecoxib 2件: Celebrex; CELECOXIB1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
62 Celiprolol 1件: Celiprolol1件: D07660 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 168
63 Cemdisiran 1件: Cemdisiran---4件: 11, 62, 66, 109
64 Cenegermin 3件: Cenegermin; OXERVATE; RhNGF1件: D11028 1件: NGFR 💬9件: Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Virion - Lyssavirus 💬2件: 53, 90
65 Cenerimod 1件: Cenerimod1件: D11283 1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬1件: 49
66 Cenicriviroc 1件: Cenicriviroc1件: D09878 2件: CCR2,
CCR5 💬		11件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬1件: 94
67 Censavudine 1件: CENSAVUDINE1件: D10550 --2件: 2, 127
68 CEP-1347 1件: CEP-1347---1件: 6
69 Cephalexin 2件: CEFALEXIN; Cephalexin2件: D00263 ,
D00906 		--1件: 299
70 Cepharanthine 2件: Cepharanthin; Cepharanthine1件: D01035 --1件: 53
71 Ceralifimod 1件: Ceralifimod---1件: 13
72 Cerliponase alfa 2件: Brineura; Cerliponase Alfa1件: D10813 1件: TPP1 💬1件: Lysosome 💬1件: 19
73 Certolizumab pegol 2件: Certolizumab Pegol; Cimzia1件: D03441 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 37, 46, 49, 96, 97, 107, 226, 271
74 Cetirizine 3件: CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE1件: D07662 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300
75 Cetrorelix 1件: Cetrorelix1件: D07665 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 46
76 Cetuximab 2件: Cetuximab; Erbitux1件: D03455 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬2件: 51, 86
77 Cevimeline 1件: Cevimeline1件: D07667 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬1件: 53
78 Chamomile 2件: Chamomile; MATRICARIA FLOWER1件: D09212 --2件: 6, 97
79 Chenodeoxycholic acid 3件: CDCA; Chenodeoxycholic acid; Chenodiol1件: D00163 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 96, 234, 263
80 Chicken 1件: Chicken---1件: 46
81 Chlorambucil 1件: Chlorambucil1件: D00266 --1件: 222
82 Chlorhexidine 2件: Chlorhexidine; Chlorhexidine Gluconate1件: D07668 --2件: 86, 299
83 Chloride ion 1件: Chloride---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
84 Chlorine 1件: Chlor---2件: 46, 271
85 Chlormezanone 0件: 1件: D00268 --1件: 13
86 Chlorogenic Acid 1件: Chlorogenic Acid---1件: 97
87 Chloroquine 1件: Chloroquine1件: D02366 --3件: 46, 49, 95
88 Chlorothiazide 1件: Chlorothiazide1件: D00519 1件: SLC12A3 💬-1件: 225
89 Chlorpheniramine 1件: Clorfenamina1件: D07398 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
90 Chlorpromazine 2件: Chlorpromazine; Chlorpromazine Hydrochloride1件: D00270 13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
91 Cholecalciferol 5件: CHOLECALCIFEROL; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
92 Cholesterol 1件: Cholesterol1件: D00040 --6件: 8, 19, 90, 160, 222, 310
93 Cholestyramine 4件: Cholestyramine; COLESTIRAMINA; COLESTYRAMINE; Questran---3件: 13, 79, 254
94 Cholic Acid 1件: CHOLIC ACID1件: D10699 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 234, 265, 310
95 Choline 1件: Choline1件: D07690 --4件: 93, 171, 193, 299
96 Chondroitin sulfate 1件: Chondroitin sulfate---2件: 96, 226
97 Chromium 1件: Chromium---1件: 46
98 Cibenzoline 1件: Cibenzoline1件: D03492 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 58
99 Ciclesonide 1件: Ciclesonide1件: D01703 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 84
100 Cicletanine 1件: Cicletanine1件: D03487 --1件: 86
101 Cidofovir 1件: Cidofovir1件: D00273 --1件: 25
102 Cilastatin 2件: CILASTATIN; Cilastatine1件: D07698 1件: DPEP1 💬-2件: 60, 299
103 Cilazapril 1件: Cilazapril2件: D01069 ,
D07699 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 66
104 Ciliary neurotrophic factor 1件: Ciliary neurotrophic factor---1件: 90
105 Cilnidipine 1件: Cilnidipine1件: D01173 5件: CACNA1B,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		41件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Nicotine addiction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 67
106 Cilofexor 1件: Cilofexor---2件: 93, 94
107 Cilostazol 2件: Cilostazol; PLETAL1件: D01896 3件: PDE3A,
PDE3B,
TBXA2R 💬		14件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 51, 70
108 Cimetidine 1件: Cimetidine1件: D00295 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
109 Cinacalcet 1件: Cinacalcet1件: D03504 1件: CASR 💬2件: NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬1件: 238
110 Cipaglucosidase alfa 1件: Cipaglucosidase Alfa1件: D11798 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
111 Ciprofloxacin 2件: CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE1件: D00186 --5件: 2, 60, 96, 97, 299
112 Cisapride 1件: CISAPRIDE2件: D00274 ,
D02092 		3件: HTR2A,
HTR3A,
HTR4 💬		7件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 13
113 Cisplatin 1件: Cisplatin1件: D00275 --1件: 28
114 Citalopram 1件: Citalopram1件: D07704 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
115 Citicoline 1件: Citicolina1件: D00057 --1件: 6
116 Citric acid 1件: Citric acid1件: D01222 --2件: 53, 291
117 Citrulline 1件: Citrulline---2件: 86, 113
118 Cladribine 4件: 2-CdA; CLADRIBINA; Cladribine; MAVENCLAD1件: D01370 1件: RRM1 💬6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬3件: 11, 13, 94
119 Clarithromycin 1件: Clarithromycin1件: D00276 --8件: 6, 63, 84, 96, 97, 222, 228, 299
120 Clavulanic acid 4件: AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID1件: D07711 --1件: 299
121 Clazakizumab 2件: BMS-945429; CLAZAKIZUMAB1件: D10312 --2件: 46, 96
122 Clemastine 2件: Clemastine; CLEMASTINE FUMARATE1件: D03535 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 13
123 Clemizole 1件: Clemizole---2件: 140, 144
124 Clenbuterol 1件: Clenbuterol1件: D07713 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 1, 2, 6, 13, 256
125 Clindamycin 2件: Clindamycin; Dalacin C phosphate1件: D00277 --2件: 46, 299
126 Clobazam 1件: CLOBAZAM1件: D01253 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 140, 144
127 Clobetasol 1件: Clobetasol1件: D07715 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬4件: 39, 46, 51, 162
128 Clobetasol propionate 1件: Clobetasol Propionate1件: D01272 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 46, 162
129 Clodronic acid 2件: Bonefos; Clasteon1件: D03545 --1件: 274
130 Clofarabine 1件: Clofarabine1件: D03546 3件: POLA1,
POLA2,
RRM1 💬		7件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 234, 326
131 Clofazimine 1件: CLOFAZIMINE1件: D00278 --1件: 96
132 Clomifene 2件: Clomiphene; Clomiphene citrate1件: D07726 2件: ESR1,
ESR2 💬		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 74
133 Clonazepam 1件: Clonazepam1件: D00280 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 6
134 Clonidine 4件: Clonidin; Clonidina; Clonidine; Clonidine hydrochloride1件: D00281 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
135 Clopidogrel 1件: Clopidogrel3件: D07729 ,
D10823 ,
D10824 		1件: P2RY12 💬1件: Platelet activation 💬3件: 49, 51, 86
136 Clostridium botulinum 1件: Clostridium botulinum---1件: 13
137 Clostridium tetani toxoid antigen (formaldehyde inactivated) 4件: Boostrix; Nimenrix; TETANUS TOXOID; Tetanus toxoid adsorbed---4件: 13, 14, 46, 50
138 Clotrimazole 1件: Clotrimazole1件: D00282 --1件: 97
139 Clozapine 1件: CLOZAPINE1件: D00283 11件: ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		8件: Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬1件: 6
140 Coagulation factor VIIa Recombinant Human 1件: RFVIIa---1件: 288
141 Coagulation factor X human 4件: Coagadex; Coagulation factor X; FACTOR X; Human Coagulation FACTOR X---1件: 288
142 Cobalt 1件: Cobalt---1件: 46
143 Cobalt chloride 1件: Ceretec---1件: 6
144 Cobamamide 1件: Cobamamide1件: D00042 --1件: 299
145 Cobimetinib 1件: Cobimetinib1件: D10405 2件: MAP2K1,
MAP2K2 💬		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 280
146 Cobiprostone 1件: Cobiprostone1件: D08893 --1件: 46
147 Cobitolimod 1件: COBITOLIMOD1件: D12275 1件: TLR9 💬9件: African trypanosomiasis, Chagas disease, Herpes simplex virus 1 infection, Malaria, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Salmonella infection, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 97
148 Cocoa 2件: Chocolate; Cocoa---1件: 6
149 Coconut 1件: Coconut---1件: 13
150 Coconut oil 1件: Coconut oil1件: D05326 --1件: 13
151 Cod liver oil 1件: Cod liver oil1件: D03578 --1件: 46
152 Cod, unspecified 0件: ---1件: 46
153 Coenzyme A 1件: Coenzyme A---1件: 246
154 Coenzyme M 2件: MESNA; UROMITEXAN---10件: 11, 13, 44, 45, 51, 60, 65, 85, 96, 164
155 Coffea arabica seed, roasted 1件: Coffee---1件: 97
156 Colchicine 2件: COLCHICINA; Colchicine1件: D00570 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬7件: 2, 42, 46, 56, 93, 210, 266
157 Colesevelam 2件: Cholestagel; Colesevelam1件: D07743 --2件: 96, 260
158 Colestipol 1件: Colestipol1件: D07771 --1件: 254
159 Colistimethate 3件: COLISTIMETHATE; COLISTIMETHATE SODIUM; Colobreathe---1件: 299
160 Colistin 1件: COLISTIN1件: D07746 --1件: 299
161 Conestat alfa 1件: COMPLEMENT C1 ESTERASE INHIBITOR1件: D10845 3件: C1R,
C1S,
KLKB1 💬		6件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Phagosome, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61
162 Conivaptan 1件: Conivaptan1件: D07748 2件: AVPR1A,
AVPR2 💬		5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 86
163 Conjugated estrogens 1件: Conjugated equine estrogens1件: D04070 --1件: 49
164 Copper 2件: Copper; Nicotinamide---4件: 2, 169, 170, 171
165 Corn 1件: Corn---2件: 46, 240
166 Corticorelin 1件: Corticotropin-releasing hormone1件: D03905 2件: CRHR1,
CRHR2 💬		4件: Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75
167 Corticorelin ovine triflutate 1件: Acthrel1件: D03592 2件: CRHR1,
CRHR2 💬		4件: Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75
168 Corticotropin 5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222
169 Cortisone 1件: Cortisone1件: D07749 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
170 Cortisone acetate 1件: Cortisone acetate1件: D00973 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
171 Corynebacterium diphtheriae 1件: Corynebacterium diphtheriae---1件: 11
172 Corynebacterium diphtheriae CRM197 protein 1件: CRM197---3件: 11, 13, 46
173 Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) 2件: Boostrix; DIPHTHERIA TOXOID---2件: 13, 46
174 Cotoretigene toliparvovec 1件: Cotoretigene Toliparvovec---1件: 90
175 Cow milk 1件: Milk---1件: 98
176 CR002 1件: CR002---1件: 299
177 CR6086 1件: CR6086---1件: 46
178 Cranberry 1件: Cranberry---1件: 13
179 Creatine 1件: Creatine---11件: 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
180 Creatinine 1件: Creatinine1件: D03600 --5件: 2, 46, 60, 70, 222
181 Creatinolfosfate 0件: 1件: D07162 --1件: 13
182 Crizotinib 1件: Crizotinib1件: D09731 1件: ALK 💬3件: Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer 💬1件: 34
183 Crocin 1件: Crocin---1件: 6
184 Cromoglicic acid 4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium1件: D07753 --3件: 2, 85, 98
185 Crovalimab 1件: CROVALIMAB1件: D11696 1件: C5 💬11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 62, 109
186 CRx-139 1件: CRX-139---1件: 46
187 CTI-1601 1件: CTI-1601---1件: 18
188 Cultivated mushroom 1件: Mushroom---2件: 6, 46
189 Curcumin 1件: Curcumin---10件: 2, 13, 46, 67, 74, 94, 96, 97, 139, 299
190 CV-MG01 1件: CV-MG01---1件: 11
191 CVnCoV 1件: SARS-COV-2 mRNA Vaccine---1件: 13
192 CX501 1件: CX501---1件: 36
193 CX516 1件: CX516---1件: 206
194 CXA-10 1件: CXA-10---2件: 86, 222
195 Cyanocobalamin 2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
196 Cyclic adenosine monophosphate 1件: AMPC---1件: 84
197 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan2件: D00287 ,
D07760 		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
198 Cyclosporine 10件: Ciclosporin; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; Restasis1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
199 Cysteamine 8件: 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI1件: D03634 --4件: 8, 19, 21, 299
200 Cysteine 2件: Cysteine; Cysteine hydrochloride---10件: 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
201 Cytarabine 1件: Cytarabine1件: D00168 --7件: 11, 13, 14, 25, 49, 60, 65