Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 8-cyclopentyl-1,3-dipropylxanthine 0件: ---1件: 299
2 Adenosine
(Synonym: Miesoo Perfect Pure Seed Cycling Ampoule)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
3 Ambroxol
(Synonym: trans-4-cyclohexanol)		1件: Ambroxol1件: D07442 --2件: 6, 19
4 Amitriptyline
(Synonym: 5-cycloheptene)		3件: Amitriptylin; Amitriptyline; Amitriptyline hydrochloride1件: D07448 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
5 Betadex
(Synonym: Cyclodextrin B)		1件: Beta-cyclodextrin1件: D02401 --1件: 19
6 Bromocriptine
(Synonym: Cycloset)		1件: Bromocriptine1件: D03165 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 74
7 Bucladesine
(Synonym: dibutyryl cyclic AMP)		1件: Bucladesine1件: D07546 16件: PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		18件: Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 246
8 Capsaicin
(Synonym: CyclobenzaprinePax)		2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
9 Ciprofloxacin
(Synonym: 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid)		2件: CIPROFLOXACIN; Ciprofloxacin hydrochloride1件: D00186 --5件: 2, 60, 96, 97, 299
10 Conjugated estrogens
(Synonym: Premplus Cycle)		1件: Conjugated equine estrogens1件: D04070 --1件: 49
11 Cyclic adenosine monophosphate 1件: AMPC---1件: 84
12 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan2件: D00287 (Name: Cyclophosphamide),
D07760 (Name: Cyclophosphamide)		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
13 Cyclosporine 10件: CICLOSPORIN; Ciclosporina; Ciclosporine; CYCLOSPORIN; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; Restasis1件: D00184 (Name: Cyclosporine)5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
14 Danazol
(Synonym: Cyclomen)		1件: Danazol1件: D00289 3件: AR,
ESR1,
PGR 💬		12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬5件: 60, 63, 64, 65, 285
15 Desogestrel
(Synonym: Cyclessa)		2件: Desogestrel; Désogestrel1件: D02367 2件: ESR1,
PGR 💬		11件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 230
16 Esketamine
(Synonym: cyclohexanone)		3件: ESKETAMINE; KETAMINE; S-ketamine1件: D07283 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬3件: 2, 4, 70
17 Ethinylestradiol
(Synonym: Cyclen Tablets)		3件: Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 7771件: D00554 1件: ESR1 💬9件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 13, 46, 49, 299
18 Gabapentin
(Synonym: Cyclo/Gaba 10/300 Pack)		4件: Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
19 Hydrocortisone cypionate
(Synonym: Cortisol 21-cyclopentanepropionate)		1件: Cortef1件: D00976 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
20 Hydroxypropyl betadex
(Synonym: 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN)		1件: 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN---1件: 19
21 Ketamine
(Synonym: 2--2-methylamino-cyclohexanone)		2件: Ketamine; NMDA1件: D08098 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 4, 6, 13, 70, 113, 156, 215
22 Lidocaine
(Synonym: Cyclopak)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
23 Magnesium oxide
(Synonym: Cyclo/Mag)		1件: Magnesium oxide1件: D01167 --3件: 6, 166, 291
24 Medroxyprogesterone acetate
(Synonym: Premplus Cycle)		1件: Medroxyprogesterone1件: D00951 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬8件: 13, 35, 46, 49, 50, 51, 60, 107
25 Montelukast
(Synonym: cyclopropaneacetic acid)		3件: Montelukast; MONTELUKAST SODIUM; Singulair1件: D08229 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
26 Naltrexone
(Synonym: N-Cyclopropylmethylnoroxymorphone)		2件: Naltrexone; Naltrexone hydrochloride1件: D05113 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
27 Nicotinamide
(Synonym: Miesoo Perfect Pure Seed Cycling Ampoule)		3件: Multivitamin; Niacinamide; Nicotinamide1件: D00036 --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
28 Norethisterone
(Synonym: Cyclafem 1/35)		3件: Norethindrone; Ortho-novum; Ortho-Novum 7771件: D00182 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬4件: 13, 46, 49, 299
29 Norgestimate
(Synonym: Ortho Tri Cyclen)		1件: Norgestimate1件: D05209 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 299
30 Oseltamivir
(Synonym: Ethyl -1-cyclohexene-1-carboxylate)		1件: Oseltamivir1件: D08306 --2件: 97, 299
31 Oxybutynin
(Synonym: 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat)		1件: Oxybutynin1件: D00465 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53
32 Pasireotide
(Synonym: cyclo)		3件: Pasireotida; PASIREOTIDE; SIGNIFOR1件: D10147 4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬		4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 67, 74, 75
33 Phenylephrine
(Synonym: Cyclomydril)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
34 Tranexamic acid
(Synonym: trans-4-cyclohexanecarboxylic acid)		1件: Tranexamic Acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬7件: 46, 70, 215, 227, 274, 288, 299