Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Otis Clapp Emagrin Forte)		4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Acetic acid
(Star-otic Solution)		2件: Acetic acid; Ethanoate1件: Acetic acid, glacial 💬 --2件: 97, 251 💬
3 Allantoin
(Burn-B Gone OTC)		1件: ALLANTOIN1件: Allantoin 💬 --1件: 36 💬
4 Aloe vera leaf
(C Ottways Lax Tab)		3件: Aloe; Aloe vera; Aloe vera gel---2件: 97, 226 💬
5 Apremilast
(Otezla)		2件: Apremilast; Otezla1件: Apremilast (Otezla) 💬 4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271 💬
6 Baricitinib 2件: BARICITINIB; OLUMIANT1件: Baricitinib (OTHER BARICITINIB) 💬 2件: JAK1,
JAK2 💬 		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
7 Betamethasone
(Betamycin Ophthalmic/otic Solution)		1件: Betamethasone1件: Betamethasone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬8件: 2, 28, 46, 65, 83, 90, 96, 235 💬
8 Calcium carbonate
(Relief OTC antacid)		3件: Calcio carbonato; Calcium; Calcium Carbonate2件: Calcium carbonate ,
Calcium carbonate 💬 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
9 Capsaicin
(Megrix OTC)		2件: Capsaicin; Qutenza1件: Capsaicin 💬 1件: TRPV1 💬 2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226 💬
10 Chlorpheniramine
(Otis Clapp Valihist)		1件: Clorfenamina1件: Chlorphenamine 💬 1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14 💬
11 Ciprofloxacin
(Cipro HC Otic Suspension)		2件: Ciprofloxacin; Ciprofloxacin hydrochloride1件: Ciprofloxacin (Otiprio) 💬 --5件: 2, 60, 96, 97, 299 💬
12 Ethanol
(hand sanitizer OTC)		3件: Alcohol; Ethanol; PREDNISONE1件: Ethanol 💬 --5件: 58, 97, 279, 280, 298 💬
13 Fluocinolone acetonide
(Otovel)		2件: Fluocinolone Acetonide; Iluvien1件: Fluocinolone acetonide (FLAC OTIC OIL) 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 90 💬
14 Gentamicin
(Garatec Otic Dps 5mg/ml)		2件: Gentamicin; Gentamicin Sulfate1件: Gentamicin 💬 --3件: 36, 113, 299 💬
15 Ginger
(C Ottways Lax Tab)		1件: Ginger1件: Ginger 💬 --2件: 46, 271 💬
16 Glycyrrhiza glabra
(C Ottways Lax Tab)		3件: Glycyrrhiza; Glycyrrhiza glabra; GLYCYRRHIZA GLABRA ROOT---2件: 53, 97 💬
17 Hydrocortisone
(Oti Rx)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: Hydrocortisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
18 Hydrocortisone acetate
(Otizol HC Liq)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: Hydrocortisone acetate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 97 💬
19 Ibuprofen
(Otis Clapp Ultraprin)		2件: IBUPROFEN; IBUPROFEN 200MG1件: Ibuprofen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299 💬
20 Lidocaine
(Otizol HC Liq)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: Lidocaine ,
Lidocaine hydrochloride monohydrate 💬 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
21 Methotrexate
(Otrexup)		6件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate1件: Methotrexate (Otrexup) 💬 2件: DHFR,
DHFR2 💬 		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
22 Moderna COVID-19 Vaccine 4件: COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax1件: Elasomeran (OTHER MODERNA COVID-19 VACCINE) 💬 --5件: 13, 46, 51, 65, 299 💬
23 Neomycin
(Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Suspension)		1件: Neomycin1件: Neomycin 💬 --3件: 96, 97, 296 💬
24 Omeprazole
(Prilosec OTC)		4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: Omeprazole 💬 2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
25 Otelixizumab
(Otelixizumab)		1件: Otelixizumab1件: Otelixizumab (Otelixizumab) 💬 3件: CD3D,
CD3E,
CD3G 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 46 💬
26 Otilimab
(Otilimab)		1件: OTILIMAB1件: Otilimab (Otilimab, Otilimab) 💬 1件: CSF2 💬 16件: Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬1件: 46 💬
27 Phenylephrine
(Otis Clapp Emagrin Forte)		1件: Phenylephrine1件: Phenylephrine 💬 3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22 💬
28 Senna leaf
(C Ottways Lax Tab)		1件: Senna1件: Senna leaf 💬 --1件: 291 💬
29 Sodium bicarbonate
(Relief OTC antacid)		1件: Sodium Bicarbonate1件: Sodium bicarbonate 💬 --1件: 299 💬
30 Tozinameran 2件: Comirnaty; Tozinameran1件: Tozinameran (OTHER BNT162B2) 💬 --5件: 13, 46, 51, 53, 299 💬
31 Zinc acetate
(Otozin)		2件: Wilzin; Zinc acetate1件: Zinc acetate 💬 --2件: 171, 299 💬
32 Zinc oxide
(Othree 50 Whitening)		1件: Zinc oxide1件: Zinc oxide 💬 --1件: 156 💬