Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Otis Clapp Mygrex)		4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Acetic acid
(Synonym: Star-otic Solution)		2件: Acetic acid; Ethanoate1件: D00010 --2件: 97, 251
3 Allantoin
(Synonym: Burn-B Gone OTC)		1件: ALLANTOIN1件: D00121 --1件: 36
4 Aloe vera leaf
(Synonym: C Ottways Lax Tab)		3件: Aloe; Aloe vera; Aloe vera gel---2件: 97, 226
5 Apremilast
(Synonym: Otezla)		2件: Apremilast; Otezla1件: D08860 (Name: Otezla (TN))4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271
6 Baricitinib 2件: BARICITINIB; Olumiant1件: D10308 (Name: OTHER BARICITINIB)2件: JAK1,
JAK2 💬		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
7 Betamethasone
(Synonym: Garasone Ophthalmic and Otic Solution)		1件: Betamethasone1件: D00244 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬8件: 2, 28, 46, 65, 83, 90, 96, 235
8 Calcium carbonate
(Synonym: Relief OTC antacid)		3件: Calcio carbonato; Calcium; Calcium Carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
9 Capsaicin
(Synonym: Megrix OTC)		2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
10 Chlorpheniramine
(Synonym: Otis Clapp Valihist)		1件: Clorfenamina1件: D07398 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
11 Ciprofloxacin
(Synonym: Otiprio)		2件: CIPROFLOXACIN; Ciprofloxacin hydrochloride1件: D00186 (Name: Otiprio (TN))--5件: 2, 60, 96, 97, 299
12 Ethanol
(Synonym: hand sanitizer OTC)		3件: Alcohol; Ethanol; PREDNISONE1件: D06542 --5件: 58, 97, 279, 280, 298
13 Fluocinolone acetonide
(Synonym: Otixal)		2件: Fluocinolone Acetonide; Iluvien1件: D01825 (Name: FLAC OTIC OIL)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
14 Gentamicin
(Synonym: Betamycin Ophthalmic/otic Solution)		2件: Gentamicin; Gentamicin Sulfate1件: D08013 --3件: 36, 113, 299
15 Ginger
(Synonym: C Ottways Lax Tab)		1件: Ginger1件: D06744 --2件: 46, 271
16 Glycyrrhiza glabra
(Synonym: C Ottways Lax Tab)		3件: Glycyrrhiza; Glycyrrhiza glabra; GLYCYRRHIZA GLABRA ROOT---2件: 53, 97
17 Hydrocortisone
(Synonym: Cipro HC Otic Suspension)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
18 Hydrocortisone acetate
(Synonym: Otizol HC Liq)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
19 Ibuprofen
(Synonym: Otis Clapp Ultraprin)		2件: Ibuprofen; IBUPROFEN 200MG1件: D00126 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
20 Lidocaine
(Synonym: Otizol HC Liq)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
21 Methotrexate
(Synonym: Otrexup)		6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate1件: D00142 (Name: Otrexup (TN))2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
22 Moderna COVID-19 Vaccine 4件: COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax1件: D12114 (Name: OTHER MODERNA COVID-19 VACCINE)--5件: 13, 46, 51, 65, 299
23 Neomycin
(Synonym: Synalar Bi-otic Solution)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
24 Omeprazole
(Synonym: Zegerid OTC)		4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: D00455 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
25 Otelixizumab 1件: Otelixizumab1件: D08959 (Name: Otelixizumab)3件: CD3D,
CD3E,
CD3G 💬		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 46
26 Otilimab 1件: OTILIMAB1件: D11343 (Name: Otilimab)1件: CSF2 💬16件: Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬1件: 46
27 Phenylephrine
(Synonym: Otis Clapp Mygrex)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
28 Senna leaf
(Synonym: C Ottways Lax Tab)		1件: Senna1件: D06751 --1件: 291
29 Sodium bicarbonate
(Synonym: Zegerid OTC)		1件: Sodium Bicarbonate1件: D01203 --1件: 299
30 Tozinameran 2件: Comirnaty; Tozinameran1件: D11971 (Name: OTHER BNT162B2)--5件: 13, 46, 51, 53, 299
31 Zinc acetate
(Synonym: Otozin)		2件: Wilzin; Zinc acetate1件: D06408 --2件: 171, 299
32 Zinc oxide
(Synonym: Coppertone Sunscreen Lotion Defend & Care Face Clearzinc + Other Sunscreen Ingredients)		1件: Zinc oxide1件: D01170 --1件: 156