Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Smart Sense Nighttime Cold and Flu Relief Multi Symptom)		4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Acetylsalicylic acid
(Synonym: Smart Sense Effervescent Antacid and Pain Relief)		2件: ACETYLSALICYLIC ACID; Aspirin1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
3 Adenosine
(Synonym: Smart Recovery)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
4 Allantoin
(Synonym: Power Defence Smart)		1件: ALLANTOIN1件: D00121 --1件: 36
5 Aluminum hydroxide
(Synonym: Smart Sense Antacid)		2件: Aluminium hydroxide; Aluminum hydroxide1件: D02416 --2件: 11, 46
6 Caffeine
(Synonym: Smart Sense Migraine Formula)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
7 Calcium carbonate
(Synonym: Smart Sense Complete)		3件: Calcio carbonato; Calcium; Calcium carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
8 Capsaicin
(Synonym: SmartRx Gaba-V Kit)		2件: Capsaicin; Qutenza1件: D00250 1件: TRPV1 💬2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226
9 Cetirizine
(Synonym: Smart Sense All Day Allergy D)		3件: CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE1件: D07662 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300
10 Chlorhexidine
(Synonym: Smart San CHG)		2件: Chlorhexidine; Chlorhexidine Gluconate1件: D07668 --2件: 86, 299
11 Chlorpheniramine
(Synonym: Smart Sense Multi Symptom Cold)		1件: Clorfenamina1件: D07398 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
12 Cimetidine
(Synonym: Smart Sense Acid Reducer)		1件: Cimetidine1件: D00295 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254
13 Citric acid
(Synonym: Smart Sense Effervescent Antacid and Pain Relief)		1件: Citric acid1件: D01222 --2件: 53, 291
14 Clotrimazole
(Synonym: Smart Sense Athletes Foot Antifungal)		1件: Clotrimazole1件: D00282 --1件: 97
15 Dextromethorphan
(Synonym: Smart Sense Severe Cold)		4件: Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
16 Dextrose, unspecified form
(Synonym: Smart Sense nausea relief)		3件: Dextrose; Glucose; Smofkabiven---16件: 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299
17 Diphenhydramine
(Synonym: Smart Sense Nightime Sleep Aid)		2件: Diphenhydramine; Diphenhydramine hydrochloride1件: D00300 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256
18 Esomeprazole
(Synonym: Smart Sense Esomeprazole Magnesium)		3件: Esomeprazole; Nexium; Omeprazole1件: D07917 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
19 Ethanol
(Synonym: Ultra Defense Sani Smart Moisturizing and Sanitizing)		3件: Alcohol; Ethanol; PREDNISONE1件: D06542 --5件: 58, 97, 279, 280, 298
20 Famotidine
(Synonym: Smart Sense Dual Action Complete)		2件: FAMOTIDINA; Famotidine1件: D00318 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107
21 Fexofenadine
(Synonym: Smart Sense Allergy Relief)		1件: Fexofenadine1件: D07958 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 46
22 Fluticasone propionate
(Synonym: Smart Sense Allergy Relief)		3件: Flovent; Fluticasone; FLUTICASONE PROPIONATE1件: D01708 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228
23 Gabapentin
(Synonym: SmartRx Gaba-V Kit)		4件: GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
24 Glycerin
(Synonym: Repiel Smart Nail Pack Miracle Butter)		2件: Bee venom; Glycerol1件: D00028 --5件: 6, 13, 79, 316, 317
25 Hydrocortisone
(Synonym: Smart Sense Anti Itch Maximum Strength)		6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
26 Hydrocortisone acetate
(Synonym: Smart Sense Anti Itch Maximum Strength)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
27 Ibuprofen
(Synonym: Smart Sense Ibuprofen Gluten Free)		2件: Ibuprofen; IBUPROFEN 200MG1件: D00126 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
28 Lansoprazole
(Synonym: Smart Sense Lansoprazole)		1件: Lansoprazole1件: D00355 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
29 Lidocaine
(Synonym: SmartRx Gaba Kit)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
30 Loperamide
(Synonym: Smart Sense anti diarrheal)		2件: Loperamide; Loperamide hydrochloride1件: D08144 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 13, 97
31 Loratadine
(Synonym: Smart Sense allergy and congestion relief indoor and outdoor allergies)		2件: Loratadina; Loratadine1件: D00364 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98
32 Magnesium hydroxide
(Synonym: Smart Sense Complete)		1件: Magnesium hydroxide1件: D00731 --1件: 284
33 Magnesium sulfate
(Synonym: Health Smart Natural Epsom Salt)		1件: Magnesium sulfate1件: D01108 --3件: 11, 296, 297
34 Mineral oil
(Synonym: Smart Sense Hemorrhoidal)		1件: Paraffin Oil1件: D05042 --1件: 291
35 Minoxidil
(Synonym: Smart Sense Hair Regrowth)		1件: MINOXIDIL1件: D00418 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179
36 Naproxen
(Synonym: Smart Sense naproxen sodium)		5件: Naprosyn; NAPROXEN; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: D00118 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271
37 Neomycin
(Synonym: Smart Sense Triple Antibiotic)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
38 Nicotine
(Synonym: Smart Sense Nicotine)		2件: NICOTINE; Nicotine gum1件: D03365 16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬		8件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬3件: 6, 13, 84
39 Omeprazole
(Synonym: Smart Sense Omeprazole)		4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: D00455 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
40 Petrolatum
(Synonym: Health Smart Lavender Baby Petroleum)		1件: Petrolatum1件: D05331 --1件: 158
41 Phenylephrine
(Synonym: Smart sense Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea Flavors)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
42 Polyethylene glycol
(Synonym: Smart Sense Clearlax)		4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 33501件: D03370 --17件: 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337
43 Pseudoephedrine
(Synonym: Smart Sense 12 Hour Decongestant)		1件: Pseudoephedrine1件: D08449 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
44 Ranitidine
(Synonym: Smart Sense Acid Reducer)		1件: Ranitidine1件: D00422 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 13, 65
45 Salicylic acid
(Synonym: Smart Release Mandelic 11 PERCENT)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
46 Sodium bicarbonate
(Synonym: Smart Sense Effervescent Antacid and Pain Relief)		1件: Sodium Bicarbonate1件: D01203 --1件: 299
47 Sodium fluoride
(Synonym: Listerine Smart Rinse Bubble Gum Shield)		1件: Sodium fluoride1件: D00943 --1件: 51
48 Thymol
(Synonym: Smart Sense Iceberg Blue)		1件: Thymol1件: D01039 --1件: 13
49 Triamcinolone
(Synonym: Smart Sense Nasal Allergy)		4件: Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE1件: D00385 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
50 Water
(Synonym: K-Mart SmartSense First Aid Contains 303 Pieces)		8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
51 Zinc acetate
(Synonym: Smart Sense Topical Analgesic Skin Protectant)		2件: Wilzin; Zinc acetate1件: D06408 --2件: 171, 299
52 Zinc oxide
(Synonym: SIMPLI DAY All In One SmartCream SPF 42)		1件: Zinc oxide1件: D01170 --1件: 156