Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Smart sense Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea Flavors)		4件: Acetaminophen; Paracetamol; Tylenol; Ultracet1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Acetylsalicylic acid
(Smart Sense Aspirin)		2件: Acetylsalicylic acid; Aspirin1件: Aspirin 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
3 Adenosine
(Smart Recovery Hydrating Toner)		2件: Adenosine; Ginseng1件: Adenosine 💬 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65 💬
4 Allantoin
(Power Defence Smart)		1件: ALLANTOIN1件: Allantoin 💬 --1件: 36 💬
5 Aluminum hydroxide
(Smart Sense Antacid)		2件: Aluminium hydroxide; Aluminum hydroxide1件: Aluminum hydroxide 💬 --2件: 11, 46 💬
6 Caffeine
(Smart Sense migraine relief)		1件: Caffeine2件: Caffeine ,
Caffeine hydrate 💬 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265 💬
7 Calcium carbonate
(Smart Sense Dual Action Complete)		3件: Calcio carbonato; Calcium; Calcium carbonate2件: Calcium carbonate ,
Calcium carbonate 💬 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
8 Capsaicin
(SmartRx Gaba-V Kit)		2件: Capsaicin; Qutenza1件: Capsaicin 💬 1件: TRPV1 💬 2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬3件: 6, 86, 226 💬
9 Cetirizine
(Smart Sense Allergy Relief)		3件: Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE1件: Cetirizine 💬 1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 28, 35, 300 💬
10 Chlorhexidine
(Smart San CHG)		2件: Chlorhexidine; Chlorhexidine Gluconate1件: Chlorhexidine 💬 --2件: 86, 299 💬
11 Chlorpheniramine
(Smart Sense Effervescent Cold Relief)		1件: Clorfenamina1件: Chlorphenamine 💬 1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14 💬
12 Cimetidine
(Smart Sense Acid Reducer)		1件: Cimetidine1件: Cimetidine 💬 1件: HRH2 💬 3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 2, 254 💬
13 Citric acid
(Smart Sense Effervescent Antacid and Pain Relief)		1件: Citric acid1件: Citric acid monohydrate 💬 --2件: 53, 291 💬
14 Clotrimazole
(Smart Sense Athletes Foot Antifungal)		1件: Clotrimazole1件: Clotrimazole 💬 --1件: 97 💬
15 Dextromethorphan
(Smart Sense tussin dm max adult)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta1件: Dextromethorphan 💬 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
16 Dextrose, unspecified form
(Smart Sense nausea relief)		3件: Dextrose; Glucose; Smofkabiven---16件: 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299 💬
17 Diphenhydramine
(Smart Sense Nightime Sleep Aid)		2件: Diphenhydramine; Diphenhydramine hydrochloride1件: Diphenhydramine 💬 1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256 💬
18 Esomeprazole
(Smart Sense Esomeprazole Magnesium)		3件: Esomeprazole; Nexium; Omeprazole1件: Esomeprazole 💬 2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299 💬
19 Ethanol
(Health Smart Hand Sanitizer Lavender)		3件: Alcohol; Ethanol; PREDNISONE1件: Ethanol 💬 --5件: 58, 97, 279, 280, 298 💬
20 Famotidine
(Smart Sense Acid Reducer)		2件: FAMOTIDINA; Famotidine1件: Famotidine 💬 1件: HRH2 💬 3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬6件: 6, 46, 61, 86, 98, 107 💬
21 Fexofenadine
(Smart Sense Allergy Relief)		1件: Fexofenadine1件: Fexofenadine 💬 1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 46 💬
22 Fluticasone propionate
(Smart Sense Allergy Relief)		3件: Flovent; Fluticasone; FLUTICASONE PROPIONATE1件: Fluticasone propionate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228 💬
23 Gabapentin
(SmartRx Gaba-V Kit)		4件: Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN1件: Gabapentin 💬 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298 💬
24 Glycerin
(Repiel Smart Hand Mask Milky Moisture)		2件: Bee venom; Glycerol1件: Glycerin 💬 --5件: 6, 13, 79, 316, 317 💬
25 Hydrocortisone
(Smart Sense Anti Itch)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: Hydrocortisone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
26 Hydrocortisone acetate
(Smart Sense Anti Itch Maximum Strength)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: Hydrocortisone acetate 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 97 💬
27 Ibuprofen
(Smart Sense ibuprofen)		2件: IBUPROFEN; IBUPROFEN 200MG1件: Ibuprofen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299 💬
28 Lansoprazole
(Smart Sense Acid Reducer)		1件: Lansoprazole1件: Lansoprazole 💬 2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299 💬
29 Lidocaine
(SmartRx Gaba Kit)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: Lidocaine ,
Lidocaine hydrochloride monohydrate 💬 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
30 Loperamide
(Smart Sense Loperamide Hydrochloride)		2件: LOPERAMIDE; Loperamide hydrochloride1件: Loperamide 💬 3件: OPRD1,
OPRK1,
OPRM1 💬 		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬2件: 13, 97 💬
31 Loratadine
(Smart Sense Allergy and Congestion Relief D)		2件: Loratadina; Loratadine1件: Loratadine 💬 1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98 💬
32 Magnesium hydroxide
(Smart Sense Complete)		1件: Magnesium hydroxide1件: Magnesium hydroxide 💬 --1件: 284 💬
33 Magnesium sulfate
(Health Smart Natural Epsom Salt)		1件: Magnesium sulfate1件: Magnesium sulfate 💬 --3件: 11, 296, 297 💬
34 Mineral oil
(Smart Sense Hemorrhoidal)		1件: Paraffin Oil1件: Mineral oil 💬 --1件: 291 💬
35 Minoxidil
(Smart Sense Hair Regrowth Treatment)		1件: MINOXIDIL1件: Minoxidil 💬 2件: ABCC8,
KCNJ11 💬 		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179 💬
36 Naproxen
(Smart Sense naproxen sodium)		5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: Naproxen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271 💬
37 Neomycin
(Smart Sense antibiotic plus pain relief)		1件: Neomycin1件: Neomycin 💬 --3件: 96, 97, 296 💬
38 Nicotine
(Smart Sense Nicotine)		2件: Nicotine; Nicotine gum1件: Nicotine 💬 16件: CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬 		8件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬3件: 6, 13, 84 💬
39 Omeprazole
(Smart Sense Omeprazole)		4件: Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM1件: Omeprazole 💬 2件: ATP4A,
ATP4B 💬 		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
40 Petrolatum
(Health Smart Baby Petroleum)		1件: Petrolatum1件: Petrolatum 💬 --1件: 158 💬
41 Phenylephrine
(Smart sense Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea Flavors)		1件: Phenylephrine1件: Phenylephrine 💬 3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22 💬
42 Polyethylene glycol
(Smart Sense Clearlax)		4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 33501件: Polyethylene glycol 3350 💬 --17件: 6, 13, 41, 46, 60, 65, 78, 96, 97, 140, 144, 235, 240, 246, 276, 299, 337 💬
43 Pseudoephedrine
(Smart Sense All Day Allergy D)		1件: Pseudoephedrine1件: Pseudoephedrine 💬 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17 💬
44 Ranitidine
(Smart Sense Acid Reducer)		1件: Ranitidine1件: Ranitidine 💬 1件: HRH2 💬 3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬2件: 13, 65 💬
45 Salicylic acid
(Smart Release Mandelic 11 PERCENT)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: Salicylic acid 💬 --1件: 97 💬
46 Sodium bicarbonate
(Smart Sense Effervescent Antacid and Pain Relief)		1件: Sodium Bicarbonate1件: Sodium bicarbonate 💬 --1件: 299 💬
47 Sodium fluoride
(Listerine Smart Rinse Anticavity Fluoride Rinse - Pink Lemonade Flavor)		1件: Sodium fluoride1件: Sodium fluoride 💬 --1件: 51 💬
48 Thymol
(Smart Sense Iceberg Blue)		1件: Thymol1件: Thymol 💬 --1件: 13 💬
49 Triamcinolone
(Smart Sense Nasal Allergy)		4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide1件: Triamcinolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
50 Water
(K-Mart SmartSense First Aid Contains 101 Pieces)		8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: Water 💬 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
51 Zinc acetate
(Smart Sense Topical Analgesic Skin Protectant)		2件: Wilzin; Zinc acetate1件: Zinc acetate 💬 --2件: 171, 299 💬
52 Zinc oxide
(Neova Smartsunscreen - Everyday)		1件: Zinc oxide1件: Zinc oxide 💬 --1件: 156 💬