Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
2 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
3 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
4 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 2件: ADRB1, ADRB2 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
5 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA1A 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
6 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
7 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
8 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
9 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA1A 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
10 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
11 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
12 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
13 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
ADRB3 1件: ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
14 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |