Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
3 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
4 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
5 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
6 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
NR3C2 1件: NR3C2 💬 |
D01115 D01115 💬 |
Eplerenone | 075 4件: 75, 113, 210, 215 💬 |
7 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
8 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
9 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
10 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
11 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
12 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
13 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
14 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
15 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
16 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
17 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
18 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
19 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
20 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
21 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
22 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
23 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
24 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
25 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
26 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
27 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
28 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
29 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 1件: OPRM1 💬 |
D00320 D00320 💬 |
Fentanyl | 046 3件: 46, 70, 215 💬 |
30 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
31 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
32 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIN1 2件: GRIN1, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
33 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
34 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
35 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
OPRM1 1件: OPRM1 💬 |
D00320 D00320 💬 |
Fentanyl | 046 3件: 46, 70, 215 💬 |
36 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
37 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
38 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
39 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
40 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
OPRM1 1件: OPRM1 💬 |
D00320 D00320 💬 |
Fentanyl | 046 3件: 46, 70, 215 💬 |
41 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
42 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
43 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
44 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
45 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
46 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
47 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
48 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
49 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
50 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
51 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
52 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
53 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 4件: 57, 58, 86, 215 💬 |
54 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
55 | Staphylococcus aureus infection 💬 Related to 12 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 7件: 46, 70, 215, 227, 274, 288, 299 💬 |
56 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
57 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |