215. ファロー四徴症 Tetralogy of Fallot Clinical trials / Disease details
臨床試験数 : 18 / 薬物数 : 26 - (DrugBank : 14) / 標的遺伝子数 : 13 - 標的パスウェイ数 : 45
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05579964 (ClinicalTrials.gov) | October 10, 2022 | 11/10/2022 | The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot | The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot | Congenital Heart Disease in Children;Cardiopulmonary Bypass;Tetralogy of Fallot | Drug: Dexmedetomidine Hcl 100 Mcg/mL Inj;Drug: Placebo | National Cardiovascular Center Harapan Kita Hospital Indonesia | NULL | Recruiting | 1 Month | 18 Years | All | 66 | Phase 2/Phase 3 | Indonesia |
| 2 | ChiCTR-IOR-16008571 | 2016-06-06 | 2016-05-31 | Premedication for children with Tetralogy of Fallot | A comparative evalution of varies premedication regimes on children with Tetralogy of Fallot | Tetralogy of Fallot | oral dexmedetomidine:oral dexmedetomidine;oral ketamine:oral ketamine;oral dexmedetomidine mixed with ketamine:oral dexmedetomidine mixed with ketamine; | Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University | NULL | Recruiting | Both | oral dexmedetomidine:20;oral ketamine:20;oral dexmedetomidine mixed with ketamine:20; | China | |||
| 3 | NCT01915277 (ClinicalTrials.gov) | April 2, 2014 | 30/7/2013 | A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics | A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics | Transposition of the Great Arteries;Tetralogy of Fallot;Ventricular Septal Defect | Drug: Dexmedetomidine | HealthCore-NERI | National Heart, Lung, and Blood Institute (NHLBI) | Completed | N/A | 180 Days | All | 119 | Phase 1 | United States |
| 4 | NCT00848393 (ClinicalTrials.gov) | November 2008 | 19/2/2009 | Measures to Lower the Stress Response in Pediatric Cardiac Surgery | Stress Response in Children Undergoing Cardiac Surgery: a Prospective Randomized Comparison Between Low Dose Fentanyl (LDF), Low Dose Fentanyl Plus Dexmedetomidine (LDF + Dex) and High Dose Fentanyl (HDF). | Tetralogy of Fallot (TOF);Ventricular Septal Defects (VSD);Atrioventricular Septal Defects (AVSD) | Drug: Fentanyl (High Dose);Drug: Fentanyl (Low Dose);Drug: Fentanyl (Low Dose) + Dexmedetomidine | Nationwide Children's Hospital | NULL | Completed | 1 Month | 3 Years | All | 52 | Phase 2 | United States |
| 5 | NCT00573066 (ClinicalTrials.gov) | May 2004 | 11/12/2007 | Understanding Dexmedetomidine In Infants Post-Operative From Cardiac Surgery | The Pharmacokinetics, Pharmacogenetics, and Pharmacodynamics of Dexmedetomidine In Infants Post-Operative From Cardiac Surgery | Hypoplastic Left Heart;Tetralogy of Fallot;Tricuspid Atresia | Drug: Dexmedetomidine | Athena Zuppa | NULL | Completed | 1 Month | 24 Months | All | 56 | Phase 1 | NULL |