Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
PML 2件: PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
2 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
3 | Adherens junction 💬 Related to 9 target genes, 19 drugs (DrugBank) and 23 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
4 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
5 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
6 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
7 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
8 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
9 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
10 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
HDAC1 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
11 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
12 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CYP11A1 1件: CYP11A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
13 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CYP11B2 1件: CYP11B2 💬 |
D11061 D11061 💬 |
Osilodrostat | 075 1件: 75 💬 |
14 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 |
15 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
NR3C2 1件: NR3C2 💬 |
D01115 D01115 💬 |
Eplerenone | 075 4件: 75, 113, 210, 215 💬 |
16 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
17 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
18 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
19 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
HDAC6 1件: HDAC6 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
20 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
21 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
HDAC4 2件: HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
22 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
23 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
24 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
25 | Bladder cancer 💬 Related to 10 target genes, 23 drugs (DrugBank) and 22 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
26 | Bladder cancer 💬 Related to 10 target genes, 23 drugs (DrugBank) and 22 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
27 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
28 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
29 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
30 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
31 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
32 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
33 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CRHR1 2件: CRHR1, CRHR2 💬 |
D03905 D03905 💬 |
Corticorelin | 075 1件: 75 💬 |
34 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CRHR1 2件: CRHR1, CRHR2 💬 |
D03592 D03592 💬 |
Corticorelin ovine triflutate | 075 1件: 75 💬 |
35 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
36 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
37 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 |
38 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
SSTR1 3件: SSTR1, SSTR2, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 3件: 67, 74, 75 💬 |
39 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
40 | Cell cycle 💬 Related to 10 target genes, 9 drugs (DrugBank) and 21 diseases in DDrare |
HDAC1 3件: HDAC1, HDAC2, HDAC8 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
41 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
42 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
43 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
44 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 |
45 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
46 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
47 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
48 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
49 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
PGR 1件: PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
50 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
51 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
52 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
53 | Chronic myeloid leukemia 💬 Related to 17 target genes, 20 drugs (DrugBank) and 29 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
54 | Circadian rhythm 💬 Related to 2 target genes, 1 drug (DrugBank) and 25 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
55 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
56 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
57 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
58 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
59 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
60 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F8 1件: F8 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
61 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
62 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
63 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
64 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
65 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
66 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
67 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CYP11A1 3件: CYP11A1, CYP11B1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
68 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 1件: 75 💬 |
69 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
70 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 |
71 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
72 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CRHR1 2件: CRHR1, CRHR2 💬 |
D03905 D03905 💬 |
Corticorelin | 075 1件: 75 💬 |
73 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CRHR1 2件: CRHR1, CRHR2 💬 |
D03592 D03592 💬 |
Corticorelin ovine triflutate | 075 1件: 75 💬 |
74 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CYP11A1 3件: CYP11A1, CYP11B1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
75 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 1件: 75 💬 |
76 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
77 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
78 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
79 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 |
80 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
PRL 1件: PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
81 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
82 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
83 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
84 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
85 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
86 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
87 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
88 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
89 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
90 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
91 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
92 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
93 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
94 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
95 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
96 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
97 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
98 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
99 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR 1件: PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
100 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA 1件: RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
101 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
102 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
103 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
104 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
105 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
106 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
107 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
108 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
109 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
110 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
111 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
112 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
113 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
SSTR2 1件: SSTR2 💬 |
D10147 D10147 💬 |
Pasireotide | 067 3件: 67, 74, 75 💬 |
114 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
115 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
116 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RARB 1件: RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
117 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
118 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
119 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
120 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
121 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
122 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
123 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
SSTR1 4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 3件: 67, 74, 75 💬 |
124 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
125 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
126 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
127 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
128 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
129 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
130 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
131 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
132 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
133 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
134 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
135 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
136 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
137 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
138 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
139 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
140 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
141 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
142 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
143 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
144 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
145 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
146 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
147 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
PRL 1件: PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
148 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
149 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
150 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
CRHR1 1件: CRHR1 💬 |
D03905 D03905 💬 |
Corticorelin | 075 1件: 75 💬 |
151 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
CRHR1 1件: CRHR1 💬 |
D03592 D03592 💬 |
Corticorelin ovine triflutate | 075 1件: 75 💬 |
152 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
153 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
154 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
155 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
156 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
157 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
158 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
159 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
160 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP11A1 3件: CYP11A1, CYP11B1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
161 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 1件: 75 💬 |
162 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP11B2 1件: CYP11B2 💬 |
D11061 D11061 💬 |
Osilodrostat | 075 1件: 75 💬 |
163 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
164 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 |
165 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
166 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
167 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
HDAC1 4件: HDAC1, HDAC2, HDAC4, HDAC5 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
168 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
169 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
170 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
171 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
172 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
173 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CRHR1 2件: CRHR1, CRHR2 💬 |
D03905 D03905 💬 |
Corticorelin | 075 1件: 75 💬 |
174 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CRHR1 2件: CRHR1, CRHR2 💬 |
D03592 D03592 💬 |
Corticorelin ovine triflutate | 075 1件: 75 💬 |
175 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD2 2件: DRD2, PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
176 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
177 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
178 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
179 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
180 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
181 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 |
182 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00088 D00088 💬 |
Hydrocortisone | 006 10件: 6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬 |
183 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
184 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
185 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D11336 D11336 💬 |
Relacorilant | 075 1件: 75 💬 |
186 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
SSTR1 4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 |
D10147 D10147 💬 |
Pasireotide | 067 3件: 67, 74, 75 💬 |
187 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
188 | Neutrophil extracellular trap formation 💬 Related to 35 target genes, 36 drugs (DrugBank) and 61 diseases in DDrare |
HDAC1 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
189 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
190 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
191 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
192 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
193 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
194 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
195 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
196 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
RARB 1件: RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
197 | Non-small cell lung cancer 💬 Related to 21 target genes, 33 drugs (DrugBank) and 45 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
198 | Notch signaling pathway 💬 Related to 7 target genes, 3 drugs (DrugBank) and 4 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
199 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PGR 1件: PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
200 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
201 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
CYP11A1 2件: CYP11A1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
202 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
203 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
204 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
205 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
206 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
207 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
208 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
209 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
210 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
211 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
212 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
213 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
214 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
215 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
216 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
217 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
218 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
219 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
220 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PML 3件: PML, RARA, RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
221 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
222 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
223 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
224 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
225 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
226 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
227 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
228 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
229 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
230 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
231 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
232 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
233 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
234 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
PRL 1件: PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
235 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
236 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
237 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
238 | Platinum drug resistance 💬 Related to 9 target genes, 15 drugs (DrugBank) and 23 diseases in DDrare |
ERBB2 1件: ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
239 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
240 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
241 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PGR 1件: PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
242 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
243 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
244 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
PRL 1件: PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
245 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
246 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
247 | Protein digestion and absorption 💬 Related to 7 target genes, 7 drugs (DrugBank) and 13 diseases in DDrare |
DPP4 1件: DPP4 💬 |
D08516 D08516 💬 |
Sitagliptin | 006 4件: 6 , 75, 233, 299 💬 |
248 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
249 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
250 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 |
251 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
252 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
253 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
254 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
255 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
256 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
257 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
258 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
F2 1件: F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 5件: 51, 75, 85, 91, 124 💬 |
259 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
F2 1件: F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 2件: 51, 75 💬 |
260 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
261 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
262 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
263 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
264 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
265 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
266 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
267 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
268 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
269 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
270 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
RARB 1件: RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
271 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
272 | Steroid hormone biosynthesis 💬 Related to 8 target genes, 11 drugs (DrugBank) and 14 diseases in DDrare |
CYP11A1 3件: CYP11A1, CYP11B1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
273 | Steroid hormone biosynthesis 💬 Related to 8 target genes, 11 drugs (DrugBank) and 14 diseases in DDrare |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 1件: 75 💬 |
274 | Steroid hormone biosynthesis 💬 Related to 8 target genes, 11 drugs (DrugBank) and 14 diseases in DDrare |
CYP11B2 1件: CYP11B2 💬 |
D11061 D11061 💬 |
Osilodrostat | 075 1件: 75 💬 |
275 | Steroid hormone biosynthesis 💬 Related to 8 target genes, 11 drugs (DrugBank) and 14 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
276 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00225 D00225 💬 |
Alprazolam | 008 2件: 8 , 75 💬 |
277 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
278 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
RARA 1件: RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
279 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
280 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
281 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
282 | Thyroid cancer 💬 Related to 8 target genes, 16 drugs (DrugBank) and 28 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
283 | Thyroid cancer 💬 Related to 8 target genes, 16 drugs (DrugBank) and 28 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
284 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
HDAC1 3件: HDAC1, HDAC2, HDAC3 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
285 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
286 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
ERBB2 1件: ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
287 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
288 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
289 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PML 2件: PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
290 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
291 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
292 | Ubiquitin mediated proteolysis 💬 Related to 2 target genes, 2 drugs (DrugBank) and 11 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
293 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
294 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
295 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
HDAC1 11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |