288. 自己免疫性後天性凝固因子欠乏症 Autoimmune acquired coagulation factor deficiency Clinical trials / Disease details

臨床試験数 : 206 / 薬物数 : 231 - (DrugBank : 28) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 21

8 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2018-001631-46-NL (EUCTR)	14/02/2019	13/02/2019	Effects of pharmacokinetic models in dosing of DDAVPand/or von Willebrand factor-containing concentr ...	Implementation of pharmacokinetic-guided dosing of DDAVPand VWF-containing concentrates in von Wille ...	Von Willebrand disease MedDRA version: 20.0;Level: LLT;Classification code 10055168;Term: Von Willeb ...	Trade Name: Minrin INN or Proposed INN: DESMOPRESSIN Trade Name: Octostim INN or Proposed INN: DESMOPRE ...	Erasmus University Medical Center	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	120	Phase 4	Netherlands
2	NCT00994929 (ClinicalTrials.gov)	January 2010	12/10/2009	Efficacy and Safety of IL-11 in DDAVP Unresponsive	Phase II Biologic Effects Study of Recombinant Interleukin-11 (rhIL-11, Neumega) in Subjects With Mo ...	Hemophilia A;Von Willebrand Disease	Biological: Neumega (Oprelvekin, Interleukin 11, IL-11)	University of Pittsburgh	NULL	Completed	18 Years	N/A	All	9	Phase 2	United States
3	EUCTR2009-017060-17-NL (EUCTR)	10/12/2009	05/11/2009	STIMULATE study: Statins influence on Minrin upregulation of von Willebrand factor and factor VIII - ...	STIMULATE study: Statins influence on Minrin upregulation of von Willebrand factor and factor VIII - ...	Type 1 von Willebrand disease and mild hemophilia A	Trade Name: simvastatine Product Name: simvastatin INN or Proposed INN: SIMVASTATIN Trade Name: Minrin P ...	Academic Medical Center	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: yes			Netherlands
4	NCT01994330 (ClinicalTrials.gov)	June 2009	14/11/2013	Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressinin Valve-Rep ...	Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressinin Valve-Rep ...	Acquired Von Willebrand Disease Secondary to Severe Aortic Stenosis;Heye´s Syndrome;Severe Aortic St ...	Drug: desmopressin	Pontificia Universidad Catolica de Chile	Ferring Pharmaceuticals	Completed	N/A	N/A	All	13	Phase 4	Chile
5	EUCTR2007-004371-19-AT (EUCTR)	20/11/2007	12/12/2007	A Phase 2 Pilot Study of the Safety, Pharmacokinetics, and Pharmacodynamics of ARC1779 Injection in ...	A Phase 2 Pilot Study of the Safety, Pharmacokinetics, and Pharmacodynamics of ARC1779 Injection in ...	von Willebrand Factor- related platelet function disorders : thrombotic thrombocytopenic purpura(TTP ...	Product Name: ARC1779 Injection Product Code: ARC1779 Other descriptive name: ARC 1779 Trade Name: Octos ...	Archemix Corp.	NULL	Not Recruiting			Female: yes Male: yes	28	Phase 2	Austria
6	EUCTR2006-001383-23-IT (EUCTR)	30/06/2006	28/11/2006	Efficacy, safety and pharmaco-economic assessment of secondary long term prophylaxis with highly pur ...	Efficacy, safety and pharmaco-economic assessment of secondary long term prophylaxis with highly pur ...	patients with severe inherited VWD unresponsive to DDAVPand with frequent bleedings MedDRA version: ...	Trade Name: ALPHANATE *INF 1F 1500UI+F 10ML INN or Proposed INN: Coagulation factor VIII Trade Name: FA ...	FONDAZIONE CENTRO EMOFILIA E TROMBOSI ANGELO BIANCHI BONOMI	NULL	Not Recruiting			Female: yes Male: yes	24	Phase 3	Spain;Germany;United Kingdom;Italy
7	EUCTR2005-004496-38-DK (EUCTR)	22/06/2006	09/05/2006	Desmopressin in the management of von Willebrand disease; Biological versus clinical efficacy.	Desmopressin in the management of von Willebrand disease; Biological versus clinical efficacy.	von Willebrand disease (VWD) is an inherited bleeding disorder, characterised mainly by mucosal blee ...	Trade Name: Octostim Product Name: Octostim Product Code: DDAVP (Desmopressin) Trade Name: Octostim Produ ...	Rigshospitalet, Copenhagen	NULL	Not Recruiting			Female: yes Male: yes	150	Phase 4	Denmark
8	NCT00111215 (ClinicalTrials.gov)	January 2001	18/5/2005	Treatment and Management of Women With Bleeding Disorders	Treatment and Management of Women With Bleeding Disorders	Menorrhagia;Blood Coagulation Disorders;Blood Platelet Disorders;Von Willebrand Disease;Hematologic ...	Drug: Tranexamic Acid;Drug: Desmopressin Acetate	Centers for Disease Control and Prevention	NULL	Completed	18 Years	50 Years	Female	100	N/A	United States

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