Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
| 2 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
BRAF 4件: BRAF, FLT4, KIT, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 3 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
CDK4 2件: CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
| 4 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
| 5 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
| 6 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
| 7 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
| 8 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 9 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 1件: 34 💬 |
| 10 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
EGFR 3件: EGFR, ERBB2, FLT4 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 11 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
| 12 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 1件: 74 💬 |
| 13 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 1件: 53 💬 |
| 14 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 1件: 53 💬 |
| 15 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 16 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
| 17 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 2件: 13, 227 💬 |
| 18 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 2件: 13, 227 💬 |
| 19 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
| 20 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 2件: 46, 49 💬 |
| 21 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
| 22 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 1件: 46 💬 |
| 23 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 3件: 2 , 113, 227 💬 |
| 24 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
| 25 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
| 26 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
FGF23 1件: FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 1件: 238 💬 |
| 27 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 28 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
FGFR1 2件: FGFR1, FLT4 💬 |
D10481 D10481 💬 |
Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬 |
| 29 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
FLT4 1件: FLT4 💬 |
D03218 D03218 💬 |
Axitinib | 034 1件: 34 💬 |
| 30 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
FLT4 1件: FLT4 💬 |
D08881 D08881 💬 |
Cediranib | 034 1件: 34 💬 |
| 31 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
FLT4 2件: FLT4, KIT 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 32 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
| 33 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 34 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
| 35 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 36 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 37 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 38 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 6件: 2 , 5 , 6 , 13, 46, 96 💬 |
| 39 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
| 40 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
KIT 1件: KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 1件: 34 💬 |
| 41 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 42 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 43 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 1件: 34 💬 |
| 44 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 45 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 46 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 47 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
| 48 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 1件: 13 💬 |
| 49 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D01217 D01217 💬 |
Dydrogesterone | 013 1件: 13 💬 |
| 50 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00950 D00950 💬 |
Levonorgestrel | 013 1件: 13 💬 |
| 51 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00951 D00951 💬 |
Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬 |
| 52 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 1件: 76 💬 |
| 53 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 1件: 75 💬 |
| 54 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D07222 D07222 💬 |
Nomegestrol | 013 1件: 13 💬 |
| 55 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D08281 D08281 💬 |
Nomegestrol acetate | 013 1件: 13 💬 |
| 56 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 4件: 13, 46, 49, 299 💬 |
| 57 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 1件: 299 💬 |
| 58 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 2件: 76, 299 💬 |
| 59 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PGR 1件: PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 1件: 10 💬 |
| 60 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
| 61 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 62 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 63 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 |