Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D07869 D07869 💬 |
Donepezil | 005 9件: 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬 |
2 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D04292 D04292 💬 |
Galantamine | 006 2件: 6 , 127 💬 |
3 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 1件: 8 💬 |
4 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D03822 D03822 💬 |
Rivastigmine | 005 3件: 5 , 6 , 13 💬 |
5 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
ACHE 1件: ACHE 💬 |
D08555 D08555 💬 |
Tacrine | 046 2件: 46, 271 💬 |
6 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
7 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1B 5件: CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 1件: 67 💬 |
8 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
9 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
10 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 1件: 6 💬 |
11 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
12 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 2件: 50, 81 💬 |
13 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 1件: 90 💬 |
14 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
15 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
16 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 4件: 58, 96, 140, 167 💬 |
17 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C 9件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
18 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
19 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 1件: 156 💬 |
20 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
21 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 3件: 6 , 13, 53 💬 |
22 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 1件: 2 💬 |
23 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 2件: 5 , 6 💬 |
24 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 1件: 6 💬 |
25 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM2 2件: CHRM2, CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 1件: 6 💬 |
26 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM2 2件: CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
27 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 1件: 53 💬 |
28 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 2件: 6 , 13 💬 |
29 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 3件: 6 , 13, 53 💬 |
30 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
31 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRNA3 6件: CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
D03365 D03365 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 |
32 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRNA4 2件: CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 3件: 6 , 18, 53 💬 |
33 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
FYN 1件: FYN 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
34 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
FYN 1件: FYN 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
35 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
36 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
37 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
38 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
39 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
KCNJ12 3件: KCNJ12, KCNJ3, KCNQ1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
40 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
KCNQ1 5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬 |
D09569 D09569 💬 |
Ezogabine | 002 2件: 2 , 144 💬 |
41 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
42 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
43 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 1件: 34 💬 |
44 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
45 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
46 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
47 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
48 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
49 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
PRKCB 1件: PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 1件: 168 💬 |