Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Non-small cell lung cancer 💬
1件: ALK 💬 D10866 💬 Brigatinib 1件: 34 💬
2 Non-small cell lung cancer 💬
1件: ALK 💬 D09731 💬 Crizotinib 1件: 34 💬
3 Non-small cell lung cancer 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
4 Non-small cell lung cancer 💬
3件: BRAF, RAF1, RET 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
5 Non-small cell lung cancer 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
6 Non-small cell lung cancer 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
7 Non-small cell lung cancer 💬
1件: EGFR 💬 D03455 💬 Cetuximab 2件: 51, 86 💬
8 Non-small cell lung cancer 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
9 Non-small cell lung cancer 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
10 Non-small cell lung cancer 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
11 Non-small cell lung cancer 💬
2件: EGFR, ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
12 Non-small cell lung cancer 💬
2件: EGFR, ERBB2 💬 D08950 💬 Neratinib 1件: 34 💬
13 Non-small cell lung cancer 💬
2件: EGFR, ERBB2 💬 D11772 💬 Tesevatinib 1件: 67 💬
14 Non-small cell lung cancer 💬
1件: JAK3 💬 D10653 💬 Peficitinib 1件: 46 💬
15 Non-small cell lung cancer 💬
1件: JAK3 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
16 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
17 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
18 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib 1件: 34 💬
19 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
20 Non-small cell lung cancer 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
21 Non-small cell lung cancer 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
22 Non-small cell lung cancer 💬
1件: PIK3CA 💬 D11011 💬 Alpelisib 1件: 138 💬
23 Non-small cell lung cancer 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
24 Non-small cell lung cancer 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
25 Non-small cell lung cancer 💬
1件: PRKCB 💬 D11935 💬 Enzastaurin 1件: 168 💬
26 Non-small cell lung cancer 💬
1件: RARB 💬 D04162 💬 Fenretinide 1件: 299 💬
27 Non-small cell lung cancer 💬
1件: RARB 💬 D00348 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
28 Non-small cell lung cancer 💬
1件: RARB 💬 D00094 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
29 Non-small cell lung cancer 💬
1件: RARB 💬 D06543 💬 Vitamin A 3件: 13, 53, 90 💬
30 Non-small cell lung cancer 💬
4件: RARB, RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin 1件: 37 💬
31 Non-small cell lung cancer 💬
4件: RARB, RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin 1件: 49 💬
32 Non-small cell lung cancer 💬
1件: RET 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
33 Non-small cell lung cancer 💬
3件: RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene 2件: 13, 75 💬