Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Platinum drug resistance 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Platinum drug resistance 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
3 Platinum drug resistance 💬
1件: ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
4 Platinum drug resistance 💬
1件: ERBB2 💬 D08950 💬 Neratinib 1件: 34 💬
5 Platinum drug resistance 💬
1件: ERBB2 💬 D11772 💬 Tesevatinib 1件: 67 💬
6 Platinum drug resistance 💬
1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
7 Platinum drug resistance 💬
1件: PIK3CA 💬 D11011 💬 Alpelisib 1件: 138 💬
8 Platinum drug resistance 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
9 Platinum drug resistance 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
10 Platinum drug resistance 💬
2件: TOP2A, TOP2B 💬 D07776 💬 Daunorubicin 1件: 65 💬
11 Platinum drug resistance 💬
2件: TOP2A, TOP2B 💬 D03730 💬 Dexrazoxane 1件: 13 💬
12 Platinum drug resistance 💬
2件: TOP2A, TOP2B 💬 D03899 💬 Doxorubicin 5件: 26, 28, 34, 65, 331 💬
13 Platinum drug resistance 💬
2件: TOP2A, TOP2B 💬 D00125 💬 Etoposide 11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
14 Platinum drug resistance 💬
2件: TOP2A, TOP2B 💬 D08224 💬 Mitoxantrone 1件: 13 💬
15 Platinum drug resistance 💬
2件: TOP2A, TOP2B 💬 D05522 💬 Pixantrone 2件: 11, 13 💬