Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
2 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 1件: 49 💬 |
3 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 1件: 49 💬 |
4 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 3件: 46, 49, 53 💬 |
5 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 6件: 13, 25, 26, 28, 56, 96 💬 |
6 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 1件: 56 💬 |
7 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 2件: 25, 34 💬 |
8 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 4件: 13, 26, 96, 97 💬 |
9 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 1件: 13 💬 |
10 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 1件: 13 💬 |
11 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 3件: 49, 65, 107 💬 |
12 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 1件: 46 💬 |
13 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
14 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IL1A 1件: IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 1件: 51 💬 |
15 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
16 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IL1A 3件: IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
17 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
18 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
19 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D11400 D11400 💬 |
Abrocitinib | 084 1件: 84 💬 |
20 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬 |
21 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 4件: 46, 51, 97, 228 💬 |
22 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
23 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
24 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 3件: 60, 65, 228 💬 |
25 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
26 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
27 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
PARP1 1件: PARP1 💬 |
D09730 D09730 💬 |
Olaparib | 086 2件: 86, 285 💬 |
28 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
29 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
30 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
31 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
32 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
33 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
34 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 |
35 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 1件: 46 💬 |
36 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 1件: 46 💬 |
37 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬 |
38 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
39 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TYK2 1件: TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 049 3件: 49, 96, 97 💬 |