Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
2 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
3 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 2件: 58, 67 💬 |
4 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 1件: 67 💬 |
5 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 4件: 66, 167, 168, 222 💬 |
6 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
7 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 3件: 66, 218, 222 💬 |
8 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 2件: 66, 67 💬 |
9 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
10 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
11 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 1件: 67 💬 |
12 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
13 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 1件: 6 💬 |
14 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
15 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 2件: 50, 81 💬 |
16 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 1件: 90 💬 |
17 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
18 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
19 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
20 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 4件: 58, 96, 140, 167 💬 |
21 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 149 1件: 149 💬 |
22 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
23 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 1件: 6 💬 |
24 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CYP11A1 3件: CYP11A1, CYP11B1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
25 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 1件: 75 💬 |
26 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
27 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
KCNA4 1件: KCNA4 💬 |
D10228 D10228 💬 |
Amifampridine | 003 3件: 3 , 11, 12 💬 |
28 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
KCNA4 1件: KCNA4 💬 |
D04127 D04127 💬 |
Dalfampridine | 003 5件: 3 , 4 , 6 , 13, 14 💬 |
29 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 |
30 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
MC2R 1件: MC2R 💬 |
D00284 D00284 💬 |
Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬 |
31 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
32 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 1件: 246 💬 |
33 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 1件: 226 💬 |
34 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
35 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |