Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
2 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 1件: 46 💬 |
3 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
4 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
5 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 1件: 6 💬 |
6 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 1件: 6 💬 |
7 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 1件: 58 💬 |
8 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D12568 D12568 💬 |
Regadenoson | 058 1件: 58 💬 |
9 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 1件: 6 💬 |
10 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
11 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D11431 D11431 💬 |
Tavapadon | 006 1件: 6 💬 |
12 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
13 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 1件: 2 💬 |
14 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
15 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D01044 D01044 💬 |
Flupentixol | 097 1件: 97 💬 |
16 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 1件: 6 💬 |
17 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
18 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D08339 D08339 💬 |
Pergolide | 006 1件: 6 💬 |
19 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
20 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 2件: 6 , 74 💬 |
21 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07593 D07593 💬 |
Buspirone | 006 2件: 6 , 51 💬 |
22 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
23 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
24 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
25 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
26 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
27 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00136 D00136 💬 |
Haloperidol | 008 1件: 8 💬 |
28 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D02666 D02666 💬 |
Iloperidone | 006 1件: 6 💬 |
29 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 2件: 6 , 86 💬 |
30 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07309 D07309 💬 |
Melperone | 006 1件: 6 💬 |
31 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00726 D00726 💬 |
Metoclopramide | 046 2件: 46, 51 💬 |
32 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 2件: 2 , 8 💬 |
33 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 1件: 6 💬 |
34 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 1件: 2 💬 |
35 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07305 D07305 💬 |
Piribedil | 006 1件: 6 💬 |
36 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 3件: 2 , 6 , 20 💬 |
37 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 3件: 2 , 6 , 8 💬 |
38 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08456 D08456 💬 |
Quetiapine | 006 2件: 6 , 13 💬 |
39 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
40 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 4件: 2 , 6 , 74, 309 💬 |
41 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D05768 D05768 💬 |
Rotigotine | 006 1件: 6 💬 |
42 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 006 2件: 6 , 70 💬 |
43 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
44 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08590 D08590 💬 |
Tiapride | 008 1件: 8 💬 |
45 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01448 D01448 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 |
46 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D08636 D08636 💬 |
Trifluoperazine | 283 2件: 283, 284 💬 |
47 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
KEAP1 1件: KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬 |
48 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOA 1件: MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 1件: 6 💬 |
49 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOA 2件: MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 1件: 6 💬 |
50 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOA 2件: MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 1件: 6 💬 |
51 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOA 3件: MAOA, MAOB, SLC6A3 💬 |
D05458 D05458 💬 |
Phentermine | 097 1件: 97 💬 |
52 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
53 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
54 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
55 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 1件: 6 💬 |
56 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
57 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 3件: 5 , 7 , 127 💬 |
58 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11293 D11293 💬 |
Gosuranemab | 005 1件: 5 💬 |
59 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11384 D11384 💬 |
Hydromethylthionine mesylate | 127 1件: 127 💬 |
60 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
61 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
62 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D08880 D08880 💬 |
Carfilzomib | 028 1件: 28 💬 |
63 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D10130 D10130 💬 |
Ixazomib | 013 5件: 13, 16, 28, 51, 61 💬 |
64 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC18A2 1件: SLC18A2 💬 |
D10701 D10701 💬 |
Deutetrabenazine | 008 1件: 8 💬 |
65 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC18A2 1件: SLC18A2 💬 |
D08575 D08575 💬 |
Tetrabenazine | 008 1件: 8 💬 |
66 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC18A2 1件: SLC18A2 💬 |
D10675 D10675 💬 |
Valbenazine | 008 1件: 8 💬 |
67 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D03215 D03215 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 |
68 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
69 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D08130 D08130 💬 |
Lisdexamfetamine | 013 1件: 13 💬 |
70 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 |
71 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SNCA 1件: SNCA 💬 |
D11420 D11420 💬 |
Prasinezumab | 006 1件: 6 💬 |
72 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SOD1 1件: SOD1 💬 |
D11811 D11811 💬 |
Tofersen | 002 1件: 2 💬 |
73 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D11595 D11595 💬 |
Belantamab mafodotin | 028 1件: 28 💬 |
74 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D09587 D09587 💬 |
Brentuximab vedotin | 049 2件: 49, 51 💬 |
75 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00570 D00570 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 |
76 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D00491 D00491 💬 |
Paclitaxel | 046 2件: 46, 85 💬 |
77 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08675 D08675 💬 |
Vinblastine | 034 2件: 34, 65 💬 |
78 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
D08679 D08679 💬 |
Vincristine | 026 4件: 26, 34, 65, 331 💬 |