Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
2 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
BRAF 3件: BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
3 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
CDK4 2件: CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
4 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
5 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
6 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
7 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
8 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
9 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 1件: 34 💬 |
10 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
11 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
FGF23 1件: FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 1件: 238 💬 |
12 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
13 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
FGFR1 3件: FGFR1, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬 |
14 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
15 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
16 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
17 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
18 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
19 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 1件: 34 💬 |
20 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
21 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
22 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
MET 1件: MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
23 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
24 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
25 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRA 2件: PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
26 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRB 1件: PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
27 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PDGFRB 1件: PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
28 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
29 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
30 | Melanoma 💬 Related to 16 target genes, 29 drugs (DrugBank) and 35 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |