Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Butalbital and Acetaminophen 50 mg/325 mg)		[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Amiloride
(Synonym: Riva-amilzide 5/50 mg)		[3] Amiloride; Amiloride Hydrochloride; Midamor[1] D07447 [3] SCNN1A,
SCNN1B,
SCNN1G 💬		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299
3 Amphotericin B
(Synonym: Amphotec 50 mg)		[2] ABELCET; Amphotericin B[1] D00203 --[1] 299
4 Atenolol
(Synonym: Riva-atenolol 50 mg)		[1] ATENOLOL[1] D00235 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167
5 Azathioprine
(Synonym: Riva-azathioprine 50 mg)		[3] Azathioprine; Azatioprina; Imuran[1] D00238 --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
6 Celecoxib
(Synonym: Celecoxib 50 mg)		[2] CELEBREX; CELECOXIB[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
7 Diclofenac
(Synonym: Apo-diclo Rapide 50 Mg Tablets)		[3] Diclofenac; Diclofenac sodium; Diclofenac SR[1] D07816 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
8 Diphenhydramine
(Synonym: Diphenhydramine Hydrochloride Caplets 50 mg)		[2] Diphenhydramine; Diphenhydramine hydrochloride[1] D00300 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256
9 Flurbiprofen
(Synonym: Ansaid Tablets 50 mg)		[1] Flurbiprofen[1] D00330 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46
10 Hydralazine
(Synonym: Nu-hydral Tab 50 mg)		[1] Hydralazine[1] D08044 [1] AOC3 💬[5] Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism 💬[1] 67
11 Hydrochlorothiazide
(Synonym: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg)		[2] Esidrix; Hydrochlorothiazide[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
12 Losartan
(Synonym: LOSARTAN POTASSIUM 50 mg)		[3] Cozaar; Losartan; LOSARTAN POTASSIUM[1] D08146 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
13 Metoprolol
(Synonym: Metoprolol Tartrate and Hydrochlorothiazide 50 mg-25 mg)		[2] Metoprolol; Metoprolol succinate[1] D02358 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226
14 Minocycline
(Synonym: Riva-minocycline 50 mg)		[3] Minocycline; Minocycline Hydrochloride; Minomycin[1] D05045 --[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299
15 Pyridoxine
(Synonym: Vitamin B-6 50 Mg Tablet)		[2] Pyridoxine; Vitamin B6[1] D08454 --[5] 6, 93, 145, 206, 320
16 Riboflavin
(Synonym: Vitamin B-2 50 Mg Tablets)		[2] Riboflavin; Vitamin B2[1] D00050 --[7] 38, 46, 96, 97, 162, 168, 265
17 Ubidecarenone
(Synonym: Coenzyme Q10 50 mg)		[3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215
18 Zinc gluconate
(Synonym: Zinc 50 Mg - Tab)		[1] ZINC GLUCONATE[1] D02390 --[1] 171