Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Rabbit [1] Rabbit---[8] 11, 13, 49, 51, 60, 65, 96, 285
2 Rabeprazole [1] Rabeprazole[1] D08463 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
3 Raclopride [1] Raclopride---[4] 5, 6, 7, 17
4 Radiprodil [1] Radiprodil---[1] 145
5 Radotinib [1] Radotinib---[1] 6
6 Ralinepag [1] RALINEPAG[1] D10725 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
7 Raloxifene [2] Raloxifene; Raloxifene hydrochloride[1] D08465 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46
8 Raltegravir [2] ISENTRESS; Raltegravir[1] D06676 --[4] 13, 26, 93, 265
9 Ramatroban [1] Ramatroban[1] D01128 [2] PTGDR,
TBXA2R 💬		[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[1] 13
10 Ramelteon [2] Ramelteon; ROZEREM[1] D02689 [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46
11 Ramipril [1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
12 Ranibizumab [3] Lucentis; Ranibizumab; RhuFab V2[1] D05697 [1] VEGFA 💬[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[4] 34, 166, 227, 301
13 Ranitidine [1] Ranitidine[1] D00422 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
14 Ranolazine [3] RANEXA; Ranolazina; Ranolazine[1] D05700 --[6] 2, 58, 86, 96, 113, 114
15 Rasagiline [4] AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate[2] D08469 ,
D10829 		[1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[6] 2, 5, 6, 17, 58, 66
16 Raspberry [1] Raspberry[1] D09179 --[1] 97
17 Ravagalimab [1] Ravagalimab[1] D11597 [1] CD40 💬[17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[2] 53, 97
18 Ravulizumab [2] RAVULIZUMAB; Ultomiris[1] D11054 [1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109
19 Rebamipide [1] Rebamipide[1] D01121 --[4] 46, 53, 97, 271
20 Rebisufligene etisparvovec [1] Rebisufligene etisparvovec---[1] 19
21 Recombinant Cholera Toxin B Subunit [1] Dukoral---[1] 97
22 Recombinant Human Thrombopoietin [2] Recombinant Human Thrombopoietin; RhTPO---[2] 60, 63
23 Regadenoson [1] Regadenoson[2] D05711 ,
D12568 		[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 58
24 Regramostim [2] GM-CSF; RhGM-CSF[1] D05712 [1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[1] 229
25 Rehmannia glutinosa root [1] Dihuang---[3] 46, 66, 76
26 Relacorilant [2] CORT125134; Relacorilant[1] D11336 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 75
27 Reldesemtiv [2] CK-2127107; RELDESEMTIV[1] D11363 [1] TNNC2 💬[1] Calcium signaling pathway 💬[2] 2, 3
28 Relebactam [1] Relebactam[1] D10726 --[1] 299
29 Remestemcel-L [3] Adult human mesenchymal stem cells; Prochymal; Remestemcel-L[1] D09719 --[3] 85, 96, 97
30 Remibrutinib [1] Remibrutinib[1] D12285 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 13, 53
31 Remifentanil [2] Remifentanil; Remifentanyl[1] D08473 [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 6, 70
32 ReN001 [1] REN001---[1] 256
33 Repaglinide [1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299
34 Reparixin [1] Reparixin[1] D08984 [2] CXCR1,
CXCR2 💬		[7] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 298, 299
35 Reproxalap [1] Reproxalap[1] D11309 --[1] 160
36 Resiniferatoxin [0] ---[5] 11, 46, 65, 222, 240
37 Reslizumab [1] Reslizumab[1] D08985 [1] IL5 💬[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 98
38 Resveratrol [1] Resveratrol---[6] 2, 8, 18, 89, 97, 113
39 Revamilast [1] Revamilast---[1] 46
40 Revusiran [1] Revusiran---[1] 28
41 Reynoutria multiflora root [1] Heshouwu---[1] 6
42 Rhamnose [1] Rhamnose---[1] 96
43 rhIGFBP-3 [1] RhIGFBP-3---[2] 113, 195
44 Ribavirin [2] Copegus; Ribavirin[1] D00423 --[2] 2, 96
45 Riboflavin [2] Riboflavin; Vitamin B2[1] D00050 --[7] 38, 46, 96, 97, 162, 168, 265
46 Ribose [1] Ribose---[1] 131
47 Rice [1] Rice---[1] 53
48 Rifabutin [1] RIFABUTIN[1] D00424 --[1] 96
49 Rifampicin [2] Rifampicin; Rifampin[1] D00211 --[9] 6, 13, 17, 46, 84, 86, 93, 299, 338
50 Rifaximin [3] Rifaximin; RIFAXIMINA; Xifaxan[1] D02554 --[9] 6, 65, 93, 94, 96, 97, 99, 296, 299
51 Rigosertib [1] Rigosertib[1] D10154 [1] PLK1 💬[4] Cell cycle, FoxO signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 36
52 Rilmenidine [2] HYPERIUM; Rilmenidine[1] D08482 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
53 Rilonacept [1] Rilonacept[1] D06635 [2] IL1A,
IL1B 💬		[45] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[4] 51, 106, 107, 266
54 Rilpivirine [1] Rilpivirine[1] D09720 --[1] 256
55 Riluzole [2] Rilutek; Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
56 Rimacalib [1] Rimacalib---[1] 46
57 Rimeporide [1] Rimeporide---[1] 113
58 Rimiducid [1] Rimiducid[1] D11195 [1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326
59 Rimonabant [2] Acomplia; Rimonabant[1] D05731 [1] CNR1 💬[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 193
60 Riociguat [2] Adempas; RIOCIGUAT[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299
61 Risankizumab [1] Risankizumab[1] D11052 [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[4] 37, 96, 97, 271
62 Risdiplam [2] EVRYSDI; Risdiplam[1] D11406 [1] SMN2 💬[1] Nucleocytoplasmic transport 💬[1] 3
63 Risedronic acid [3] Risedronate; Risedronate sodium; Risedronic acid[1] D08484 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
64 Risperidone [1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
65 Ritonavir [2] Norvir; Ritonavir[1] D00427 --[3] 2, 86, 265
66 Rituximab [6] MabThera; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
67 Rivaroxaban [2] Rivaroxaban; Xarelto[1] D07086 [1] F10 💬[1] Complement and coagulation cascades 💬[4] 46, 49, 91, 210
68 Rivastigmine [3] EXELON; Rivastigmine; Rivastigmine Transdermal System[1] D03822 [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
69 Rivenprost [1] Rivenprost---[1] 97
70 Rocuronium [2] Rocuronium; Rocuronium Bromide---[2] 70, 296
71 Rofecoxib [1] Rofecoxib[1] D00568 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
72 Roflumilast [1] Roflumilast[1] D05744 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[4] 84, 97, 206, 299
73 Rolipram [1] Rolipram[1] D01783 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13
74 Romiplostim [2] NPLATE; Romiplostim[1] D08990 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65
75 Romosozumab [2] Evenity; ROMOSOZUMAB[1] D10156 [1] SOST 💬[2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274
76 Rontalizumab [1] Rontalizumab[1] D09662 [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
77 Ropinirole [3] REQUIP; Ropinirole; Ropinirole Hydrochloride[1] D08489 [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
78 Ropivacaine [2] Ropivacaine; Ropivacaine Hydrochloride Injection[1] D08490 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[4] 22, 36, 46, 70
79 Rosiglitazone [2] Rosiglitazone; Rosiglitazone maleate[1] D08491 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
80 Rosuvastatin [3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[1] D08492 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
81 Rotigotine [3] NEUPRO; ROTIGOTINA; ROTIGOTINE[1] D05768 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
82 Roxithromycin [1] Roxithromycin[1] D01710 --[2] 46, 299
83 Royal jelly [1] Royal jelly[1] D09754 --[1] 49
84 Rozanolixizumab [1] ROZANOLIXIZUMAB[1] D12182 [1] FCGRT 💬-[3] 11, 14, 63
85 Rubella virus vaccine [1] M-M-RVAXPRO---[1] 107
86 Rubidium [1] Rubidium---[1] 84
87 Rufinamide [2] Inovelon; RUFINAMIDE[1] D05775 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 144
88 Rupatadine [1] Rupatadine[1] D07407 [2] HRH1,
PTAFR 💬		[4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[1] 46
89 Rurioctocog alfa pegol [1] Rurioctocog alfa pegol[1] D10760 --[1] 288
90 Ruxolitinib [1] Ruxolitinib[1] D09959 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[3] 60, 65, 228